Article
Materials Science, Coatings & Films
Shiyuan Wang, Tong Guo, Gang Xu, Feng Ding
Summary: The corrosion behavior of Zn-Al-Mg pseudo-alloy coatings was studied, revealing the significant influence of Zn content on corrosion mechanism, kinetics, pathway, and products. Selective dissolution was observed due to phase segregation caused by multigalvanic systems. Improved corrosion resistance was observed in both coatings due to the barrier effect of Al-Mg splats and sacrificial protection provided by Zn-rich splats.
SURFACE & COATINGS TECHNOLOGY
(2023)
Article
Materials Science, Coatings & Films
K. S. Akshay, V. P. Muhammad Rabeeh, Shebeer A. Rahim, K. P. Sijina, G. K. Rajanikant, T. Hanas
Summary: This study investigates the effect of alginate/bioglass composite coating on the biodegradation, bioactivity and biocompatibility of Mg-Ca alloy. The results show that the coated sample has better degradation resistance and bioactivity, and promotes biomineralization and cell adhesion.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Nima Pourakbar Zehtabi, Amir Ardeshiri Lordejani, Mario Guagliano, Sara Bagherifard
Summary: Cold spray technology, as a solid-state deposition method, has the potential for deposition of high-entropy alloys and medium-entropy alloys. A finite element model is developed to simulate the deposition process, which can guide the experimental parameter selection and reduce the cost.
ADVANCED ENGINEERING MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
J. Sivaramapandian, M. Prem Ananth, R. Selvabharathi
Summary: In this research, the mechanical properties and corrosion resistance of AZ31 Mg alloy were improved through shot peening and plasma spray coating processes. The results showed significant effects of shot peening and coating processes on the Mg grain boundaries and recrystallization growth. The post-shot peening coated and pre-coated shot peening samples exhibited higher elongation and hardness values, as well as better corrosion resistance and surface properties.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Materials Science, Multidisciplinary
Qiang Wang, Nan Li, Liucheng Zhou, Wenjuan Niu, Peng Han, Xinlei Pan, Yu Han, Pu Song, Ning Hu
Summary: This paper studies the impact of cold spray and super-sonic laser deposition (SLD) repair techniques on damaged components and improves the fatigue performance through laser shock peening treatment. The results show that the fatigue limit of the repaired specimens exceeded that of the original specimen, providing a new high-quality repair method.
MATERIALS CHARACTERIZATION
(2023)
Article
Materials Science, Ceramics
Ziyu Ding, Qianhong Yuan, Hao Wang, Yinghong Tang, Yimin Tan, Quanguo He
Summary: A Nb2O5/Mg gradient coating was synthesized on AZ31 magnesium alloy through magnetron sputtering, which showed improved mechanical, anti-wear, and anti-corrosion properties. The coating had an amorphous columnar structure and a gradual change in chemical composition, reducing residual stress and increasing compactness. Compared to a Nb2O5 single-layer film, the gradient coating exhibited increased adhesion, hardness, elastic modulus, and reduced wear rate. Moreover, it showed better corrosion resistance. This study provides a strategy for enhancing ceramic coatings on magnesium alloy for medical applications.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Coatings & Films
Yuejun Ouyang, Zhifeng Huang, Rui Fang, Liang Wu, Qiwen Yong, Zhi-Hui Xie
Summary: A stable composite coating with good superhydrophobicity and corrosion resistance was successfully fabricated on magnesium alloy surface through chemical deposition and electrodeposition. The addition of SiO2 nanoparticles in the coating showed optimal superhydrophobic properties. Electrochemical tests indicated excellent corrosion protection of the composite coating.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Puneet Bansal, Gurpreet Singh, Hazoor Singh Sidhu
Summary: Plasma-sprayed pure HA and HA/Sr reinforced coatings significantly improved the surface properties and corrosion resistance of Mg alloys, showing promise for future bone implant applications.
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2021)
Article
Chemistry, Physical
Marina Samodurova, Nataliya Shaburova, Olga Samoilova, Ahmad Ostovari Moghaddam, Kirill Pashkeev, Vladimir Ul'yanitckiy, Evgeny Trofimov
Summary: This paper focuses on the characterization of WC-10Co-4Cr coating deposited on an Al-4Cu-1Mg alloy using detonation spray method. The results showed that the coating has low porosity and refined carbide grains. The variation of spraying distance did not influence the coating microstructure and composition.
Article
Materials Science, Multidisciplinary
Yongtao Bao, Binguo Fu, Yunlei Jiao, Tianshun Dong, Jingkun Li, Guolu Li
Summary: To enhance the surface properties of Mg-Li alloy, a TC4 alloy coating was prepared using the cold spray technique. The interface between the coating and the Mg-Li alloy substrate showed mechanical bonding without significant defects. The cold sprayed TC4 alloy coating exhibited better wear resistance and corrosion resistance.
Article
Materials Science, Coatings & Films
Y. Zhang, Y. J. Guo, J. Y. Dai, L. Zhao, L. P. Wu
Summary: A hazenite coating was developed on AZ31 Mg alloy using an immersion method, and the formation mechanism was investigated through the analysis of coating morphology, structure, and composition. The results showed that the coating consisted of two layers, which greatly reduced the corrosion rate of the AZ31 Mg alloy substrate.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Engineering, Mechanical
Bing -yuan Han, Xiang-han Gao, Shu-ying Chen, Meng-qi Cong, Ren-xing Li, Xiao Liu, Wei-xing Hang, Fang -fang Cui
Summary: This paper investigated the microstructure and tribological behavior of Ni60 alloy coating prepared by plasma spray on the surface of aluminum alloy. The results showed that the coating thickness and spraying power had an impact on the coating performance, with multiple phases and materials present in the coating. The coating had enhanced hardness and oxidation resistance, but also had a higher porosity. Under high load, the coating exhibited increased wear and friction coefficient. Moderate spraying power improved the coating's wear resistance.
TRIBOLOGY INTERNATIONAL
(2022)
Article
Materials Science, Multidisciplinary
Yuqin Rao, Qun Wang, Jinxiong Chen, Chidambaram Seshadri Ramachandran
Summary: By employing Cold Spray and Plasma Electrolytic Oxidation techniques, a double-layered coating was successfully fabricated to enhance the surface properties and wear resistance of AZ31 Magnesium alloy. The Al-based PEO coating exhibited superior microstructure, hardness, and bond strength compared to the Mg-based PEO coating, providing better protection against abrasion, corrosion, and wear.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Lin Hou, Shu Guo, Shanguang Liu, Pei Wang, Yan Zhao, Haichao Li
Summary: In this study, the effect of trace Sc on the mechanical property and high-temperature creep performance of the spray-deposited Al-Zn-Mg-Cu alloy was investigated. The addition of Sc significantly refined the microstructure of the alloy and decreased the area fraction of precipitates at grain boundaries. This resulted in improved mechanical property and high-temperature creep resistance, which can be attributed to the formation of fine and dispersed Al3(Sc, Zr) secondary phase particles.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Materials Science, Coatings & Films
Stefania Morelli, Giuseppe Rombola, Giovanni Bolelli, Mattia Lopresti, Pietro Puddu, Enrico Boccaleri, Luca Seralessandri, Luca Palin, Veronica Testa, Marco Milanesio, Luca Lusvarghi
Summary: Magnesium alloys, especially AZ31, have great potential in energy saving and emissions reduction, but their surfaces are prone to corrosion, requiring coatings for protection. High Velocity Oxygen-Fuel (HVOF) thermal spray can deposit WC-CoCr coatings with high surface hardness, but factors like torch-substrate kinematics and substrate surface preparation need to be carefully considered during deposition.
SURFACE & COATINGS TECHNOLOGY
(2022)
Review
Materials Science, Multidisciplinary
Farnaz Ghorbani, Theresa Reiter, Liliana Liverani, Dirk W. Schubert, Aldo R. Boccaccini, Judith A. Roether
Summary: Electrospinning is a promising method for designing fibrous tissue engineering scaffolds for hard and soft tissues. Incorporating bioactive cues, such as bioactive glass (BG), into electrospun biopolymer fibers has shown potential in improving fiber properties and enhancing biological performance. This article provides a comprehensive overview of BG-containing electrospun polymer composite fibers and discusses their effects on mechanical properties, biological response, and applications in bone regeneration, wound healing, and drug delivery. The study highlights essential aspects for future translational research in tissue engineering using BG-polymer composite fibers.
ADVANCED ENGINEERING MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Giovanni Falcone, Sonja Kuth, Aldo R. Boccaccini, Rita P. Aquino, Tiziana Esposito, Paola Russo
Summary: To fully utilize the potential of 3D printing, particularly in the case of semisolid extrusion (SSE), the technological challenges need to be addressed. This study focuses on investigating the physicochemical properties of natural polymers, specifically alginate hydrogel, for 3D printing tablets that are easy to swallow. By adding sorbitol as a plasticizer, the aim is to improve the swallowability of the tablets. Different concentrations of sorbitol solution are evaluated to determine the best composition in terms of printing and technological properties. The results highlight a predictable relationship between the amount of sorbitol loaded and the residual mass of the final platforms.
ADVANCED ENGINEERING MATERIALS
(2023)
Article
Engineering, Biomedical
A. Weizel, T. Distler, R. Detsch, A. R. Boccaccini, H. Seitz, S. Budday
Summary: Numerical simulations using appropriate material models and parameters are valuable for understanding the effects of mechanical stimulation on hydrogels for cartilage replacement. In this study, hyperviscoelastic material parameters for human articular cartilage and two replacement materials were identified using COMSOL Multiphysics (R) v. 5.6. The results revealed that ADA-GEL and ChondroFiller(liquid) exhibit faster stress relaxation and lower relaxation time constants compared to cartilage. Additionally, ADA-GEL and ChondroFiller(liquid) have a predominant elastic response, while cartilage has a predominant viscoelastic response.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Letter
Materials Science, Multidisciplinary
Qaisar Nawaz, Thomas Fiedler, Jonas Biggemann, Tobias Fey, Aldo R. Boccaccini
Summary: In order to improve the mechanical properties of 45S5 bioactive glass struts, the study investigates the fabrication of struts using mold casting and sintering, followed by coating with gelatine and polycaprolactone (PCL). The results show an improvement in flexural strength of the struts after coating with PCL.
Article
Materials Science, Multidisciplinary
F. Maciag, T. Moskalewicz, K. Cholewa-Kowalska, Z. Hadzhieva, M. Dziadek, A. Lukaszczyk, A. R. Boccaccini
Summary: The objective of this study was to develop cathodic electrophoretic deposition (EPD) to obtain composite coatings of mesoporous sol-gel glass (MSGG) particles embedded in a zein matrix on Ti-13Nb-13Zr substrates. The EPD process successfully produced uniform coatings with open porosity and good adhesion to the substrates. The coated substrates exhibited improved resistance to electrochemical corrosion, as well as moderate hydrophilicity and roughness. The composite coatings also showed enhanced antibacterial properties and the ability to form hydroxyapatite.
METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Alessia Peserico, Chiara Di Berardino, Giulia Capacchietti, ChiaraCamerano Spelta Rapini, Liliana Liverani, Aldo Roberto Boccaccini, Valentina Russo, Annunziata Mauro, Barbara Barboni
Summary: Comparing with the validated cumulus-oocyte complex (COC) protocol, a three-dimensional (3D) scaffold-mediated follicle-enclosed oocytes (FEO) system was found to optimize in vitro maturation (IVM) for ovine early antral (EA)-derived oocytes. By combining hCG stimulation with ovarian surface epithelium (OSE) cells coculture exclusively on the FEO system, the maturation rate and parthenogenetic activation of EA-derived oocytes were significantly improved. The paracrine factors released specifically from OSE enhanced the hCG-triggering of oocyte maturation mechanisms by acting through the mural compartment, stimulating the EGFR signaling.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Materials Science, Multidisciplinary
Annabel Braem, Nur Hidayatul Nazirah Kamarudin, Nitu Bhaskar, Zoya Hadzhieva, Andrea Mele, Jeremy Soulie, Denver P. Linklater, Linda Bonilla-Gameros, Aldo R. Boccaccini, Ipsita Roy, Christophe Drouet, Elena P. Ivanova, Diego Mantovani, Bikramjit Basu
Summary: Peri-implant infection is a significant challenge in the clinical field. Researchers are developing biomaterial and bioengineering-based antimicrobial strategies to tackle this issue. However, the development of these approaches is hindered by challenges like biocompatibility concerns, reduced antimicrobial effectiveness, long-term stability issues, and antibiotic resistance development. This review provides insights into current state-of-the-art biomaterial-based antimicrobial approaches and highlights the importance of translational research strategies and regulatory frameworks for clinical implementation. The integration of computational tools and experimental databases using artificial intelligence (AI) is proposed as a vision to accelerate the development of next-generation biomaterial-based antimicrobial strategies.
INTERNATIONAL MATERIALS REVIEWS
(2023)
Article
Materials Science, Biomaterials
Irem Unalan, Stefan Schruefer, Dirk W. Schubert, Aldo R. Boccaccini
Summary: This study aimed to develop 3D-printed hydrogels as multifunctional wound dressings containing phytotherapeutic agents. Results showed that blending xanthan gum (XAN) overcame the challenges associated with sodium alginate (ALG) in terms of printability and shape fidelity. Clove essential oil (CLV) was successfully incorporated into the 3D-printed hydrogels, exhibiting long-term release and enhanced antioxidant and antibacterial activity. Additionally, CLV showed potential anti-inflammatory effects and had no toxic effect on NHDF cells. Overall, this study highlights the potential benefits of incorporating natural phytotherapeutics into 3D-printed hydrogels for wound healing.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Oncology
Joerg Fellenberg, Sarina Losch, Max R. Marinescu, Birgit Frey, Burkhard Lehner, Marcela Arango-Ospina, Zoya Hadzhieva, Aldo R. Boccaccini, Fabian Westhauser
Summary: The cytotoxic effects of bioactive glasses (BGs) on giant cell tumor (GCTB) cell lines were observed in vitro, and a significant reduction in tumor formation and growth was seen in the chicken chorioallantoic membrane (CAM) assay. These findings suggest that BGs could be potential candidates for the treatment of GCTBs.
Article
Pharmacology & Pharmacy
Mirna L. Sanchez, Hugo Valdez, Micaela Conde, Pamela Viana-Mendieta, Aldo R. Boccaccini
Summary: This article discusses the development of biomaterial platforms using functional hydrogels for delivering reagents of interest in the field of biomedicine. In situ dosing of therapeutic components for dermatological injuries, such as diabetic foot ulcers, is a novel strategy to improve wound healing. Hydrogels have shown advantages over other therapies in terms of comfort and their compatibility with tissues. The paper also proposes a new approach to wound care by modulating macrophage polarization using advanced biomaterials.
Article
Biochemistry & Molecular Biology
Marta Clerici, Vera Citro, Amy L. Byrne, Tina P. Dale, Aldo R. Boccaccini, Giovanna Della Porta, Nicola Maffulli, Nicholas R. Forsyth
Summary: By comparing and contrasting different tendon cell populations, this study found that type II tendon stem cells (TSCs) are the most promising population for expansion due to their enhanced proliferative potential, multipotency, and maintenance of a tendon-specific profile. Furthermore, physoxia promotes enhanced proliferation and maintenance of a tenogenic profile in all tendon-derived cell populations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Electrochemistry
F. Maciag, T. Moskalewicz, K. Cholewa-Kowalska, Z. Hadzhieva, M. Dziadek, B. Dubiel, A. Lukaszczyk, A. R. Boccaccini
Summary: Cu- and Mg-doped mesoporous sol-gel bioactive glasses were developed and their microstructure was investigated. The electrophoretic deposition conditions for composite coatings on Ti-13Nb-13Zr substrates were determined. The coated alloy showed enhanced resistance to electrochemical corrosion and improved antibacterial properties compared to pure zein.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Article
Materials Science, Ceramics
Q. Nawaz, A. de Pablos-Martin, A. T. Contreras Jaimes, F. Scheffler, T. Wagner, D. S. Brauer, A. R. Boccaccini
Summary: This study compares the properties of scaffolds prepared using sol-gel and melt-derived powders. The microstructure, shrinkage behavior, bioactivity, and cell compatibility of the scaffolds were evaluated. The findings show that sol-gel derived 13-93 scaffolds exhibit similar characteristics to melt-derived scaffolds, and the sol-gel approach offers advantages such as low temperature processing and high purity for fabricating high-quality scaffolds.
Article
Chemistry, Multidisciplinary
Catalina Adler, Mahshid Monavari, Gustavo A. Abraham, Aldo R. Boccaccini, Farnaz Ghorbani
Summary: This study synthesized electroconductive silane-modified gelatin-poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) scaffolds to simulate the chemistry and piezoelectricity of bone. The scaffolds were functionalized with polydopamine (PDA) inspired by mussels to enhance hydrophilicity, cell interaction, and biomineralization. Analysis showed that the PDA-coated scaffolds had improved electrical resistance, hydrophilicity, compressive strength, modulus, and biomineralization capability. The scaffolds also promoted the viability, adhesion, proliferation, alkaline phosphatase expression, and HA deposition of MG-63 cells, indicating their potential for bone regeneration.
Article
Engineering, Biomedical
Hazel O. Simila, Ana M. Beltran, Aldo R. Boccaccini
Summary: This study investigated the antimicrobial and mechanical properties of dental floss coated with chitosan or chitosan + mesoporous bioactive glass nanoparticles. The coatings showed significant ability to inhibit bacterial growth after 24 hours, although the impact was minimal at 3 hours. Furthermore, the addition of these layers improved the tensile strength of the floss, making it more effective for cleaning between teeth. Enhanced investigations of these composites are therefore proposed due to their potential in promoting oral health.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2023)
