Reprogramming the rapid clearance of thrombolytics by nanoparticle encapsulation and anchoring to circulating red blood cells

Vascular Drug Delivery Using Carrier Red Blood Cells: Focus on RBC Surface Loading and Pharmacokinetics

(2020) Patrick M. Glassman et al.   Pharmaceutics

Making a case for the right ‘-ase’ in acute ischemic stroke: alteplase, tenecteplase, and reteplase

(2019) Katleen Wyatt Chester et al.   Expert Opinion On Drug Safety

In-situ vaccination using focused ultrasound heating and anti-CD-40 agonistic antibody enhances T-cell mediated local and abscopal effects in murine melanoma

(2019) Mohit Pratap Singh et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Erythrocyte leveraged chemotherapy (ELeCt): Nanoparticle assembly on erythrocyte surface to combat lung metastasis

(2019) Zongmin Zhao et al.   Science Advances

The Hemocompatibility of Nanoparticles: A Review of Cell–Nanoparticle Interactions and Hemostasis

(2019) Kara de la Harpe et al.   Cells

Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity

(2018) Yuan Zhang et al.   Nature Communications

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude

(2018) Jacob S. Brenner et al.   Nature Communications

Nanoparticle Properties Modulate Their Attachment and Effect on Carrier Red Blood Cells

(2018) Daniel C. Pan et al.   Scientific Reports

Immune oncology, immune responsiveness and the theory of everything

(2018) Tolga Turan et al.   Journal for ImmunoTherapy of Cancer

Tissue plasminogen activator-based nanothrombolysis for ischemic stroke

(2017) Shan Liu et al.   Expert Opinion on Drug Delivery

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes

(2017) Peter Popp Wibroe et al.   Nature Nanotechnology

Erythrocyte membrane skeleton inhibits nanoparticle endocytosis

(2017) Xinli Gao et al.   AIP Advances

Recombinant human TNK tissue-type plasminogen activator (rhTNK-tPA) versus alteplase (rt-PA) as fibrinolytic therapy for acute ST-segment elevation myocardial infarction (China TNK STEMI): protocol for a randomised, controlled, non-inferiority trial

(2017) Hai-bo Wang et al.   BMJ Open

Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems

(2016) Carlos H. Villa et al.   ADVANCED DRUG DELIVERY REVIEWS

In situvaccination for the treatment of cancer

(2016) Linda Hammerich et al.   Immunotherapy

Nanoparticle Attachment to Erythrocyte Via the Glycophorin A Targeted ERY1 Ligand Enhances Binding without Impacting Cellular Function

(2016) Kaustuv Sahoo et al.   PHARMACEUTICAL RESEARCH

Safe and Immunocompatible Nanocarriers Cloaked in RBC Membranes for Drug Delivery to Treat Solid Tumors

(2016) Brian T. Luk et al.   Theranostics

Detoxification of Organophosphate Poisoning Using Nanoparticle Bioscavengers

(2015) Zhiqing Pang et al.   ACS Nano

Exploiting shape, cellular-hitchhiking and antibodies to target nanoparticles to lung endothelium: Synergy between physical, chemical and biological approaches

(2015) Aaron C. Anselmo et al.   BIOMATERIALS

Nanoparticle uptake: The phagocyte problem

(2015) Heather Herd Gustafson et al.   Nano Today

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Interaction of Amorphous Silica Nanoparticles with Erythrocytesin Vitro: Role of Oxidative Stress

(2014) Abderrahim Nemmar et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cell-mediated delivery of nanoparticles: Taking advantage of circulatory cells to target nanoparticles

(2014) Aaron C. Anselmo et al.   JOURNAL OF CONTROLLED RELEASE

Sustained Release of Metformin via Red Blood Cell Accumulated Sulfenamide Prodrug

(2014) Lauri Peura et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

(2014) J. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivering Nanoparticles to Lungs while Avoiding Liver and Spleen through Adsorption on Red Blood Cells

(2013) Aaron C. Anselmo et al.   ACS Nano

Red blood cells decorated with functionalized core–shell magnetic nanoparticles: elucidation of the adsorption mechanism

(2013) Thanh Duc Mai et al.   CHEMICAL COMMUNICATIONS

Protease-resistant peptide design-empowering nature's fragile warriors against HIV

(2012) Matthew T. Weinstock et al.   BIOPOLYMERS

Tumor-Infiltrating Lymphocyte Grade Is an Independent Predictor of Sentinel Lymph Node Status and Survival in Patients With Cutaneous Melanoma

(2012) Farhad Azimi et al.   JOURNAL OF CLINICAL ONCOLOGY

PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics

(2012) Jillian L. Perry et al.   NANO LETTERS

Effect of ligand density, receptor density, and nanoparticle size on cell targeting

(2012) Drew R. Elias et al.   Nanomedicine-Nanotechnology Biology and Medicine

Engineering antigens for in situ erythrocyte binding induces T-cell deletion

(2012) S. Kontos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of Mesoporous Silica Nanoparticles with Human Red Blood Cell Membranes: Size and Surface Effects

(2011) Yannan Zhao et al.   ACS Nano

Advanced procedures for labeling of antibodies with quantum dots

(2011) Wael Mahmoud et al.   ANALYTICAL BIOCHEMISTRY

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Biodistribution and Clearance Studies Using Multimodal Organically Modified Silica Nanoparticles

(2010) Rajiv Kumar et al.   ACS Nano

Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation

(2010) S. Zaitsev et al.   BLOOD

Factors that Control the Circulation Time of Nanoparticles in Blood: Challenges, Solutions and Future Prospects

(2010) Jin-Wook Yoo et al.   CURRENT PHARMACEUTICAL DESIGN

Drug delivery by red blood cells: vascular carriers designed by mother nature

(2010) Vladimir R Muzykantov   Expert Opinion on Drug Delivery

An ultrasound-responsive nano delivery system of tissue-type plasminogen activator for thrombolytic therapy

(2010) Yoshiko Uesugi et al.   JOURNAL OF CONTROLLED RELEASE

The Complex Role of Multivalency in Nanoparticles Targeting the Transferrin Receptor for Cancer Therapies

(2010) Jin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding Ligand Distributions in Modified Particle and Particlelike Systems

(2010) Ilhem F. Hakem et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improving Protein Pharmacokinetics by Engineering Erythrocyte Affinity

(2010) Stephan Kontos et al.   MOLECULAR PHARMACEUTICS

Synthetic therapeutic peptides: science and market

(2009) Patrick Vlieghe et al.   DRUG DISCOVERY TODAY

Tissue-type plasminogen activator as a therapeutic target in stroke

(2008) Iordanis Gravanis et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Fluorescent Silica Nanoparticles with Efficient Urinary Excretion for Nanomedicine

(2008) Andrew A. Burns et al.   NANO LETTERS

Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

(2008) Michelle Longmire et al.   Nanomedicine

Seven challenges for nanomedicine

(2008) Wendy R. Sanhai et al.   Nature Nanotechnology