LncRNA MEG3 regulates microglial polarization through KLF4 to affect cerebral ischemia-reperfusion injury

Silencing of MEG3 inhibited ox‐LDL‐induced inflammation and apoptosis in macrophages via modulation of the MEG3/miR‐204/CDKN2A regulatory axis

(2019) Long Yan et al.   CELL BIOLOGY INTERNATIONAL

LncRNA SNHG12 as a potent autophagy inducer exerts neuroprotective effects against cerebral ischemia/reperfusion injury

(2019) Xiaoxi Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Baicalein administered in the subacute phase ameliorates ischemia-reperfusion-induced brain injury by reducing neuroinflammation and neuronal damage

(2019) Shilun Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Long non-coding RNA MEG3 promotes cerebral ischemia-reperfusion injury through increasing pyroptosis by targeting miR-485/AIM2 axis

(2019) Ji Liang et al.   EXPERIMENTAL NEUROLOGY

Meisoindigo Protects Against Focal Cerebral Ischemia-Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation and Regulating Microglia/Macrophage Polarization via TLR4/NF-κB Signaling Pathway

(2019) Yingze Ye et al.   Frontiers in Cellular Neuroscience

Long Non-Coding RNA MEG3 Promotes Apoptosis of Vascular Cells and is Associated with Poor Prognosis in Ischemic Stroke

(2019) Meiping Wang et al.   Journal of Atherosclerosis and Thrombosis

Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke

(2018) Bing Han et al.   Autophagy

KLF4 protects brain microvascular endothelial cells from ischemic stroke induced apoptosis by transcriptionally activating MALAT1

(2018) Haojie Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long Noncoding RNAs: New Players in Ischaemia-Reperfusion Injury

(2018) Si-yang Yu et al.   Heart Lung and Circulation

Dexmedetomidine attenuates cerebral ischemia/reperfusion injury in neonatal rats by inhibiting TLR4 signaling

(2018) Jiangxia Cheng et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Analysis of long non-coding RNA expression profiles following focal cerebral ischemia in mice

(2018) Cuiying Liu et al.   NEUROSCIENCE LETTERS

Long non-coding RNAs in ischemic stroke

(2018) Mei-Hua Bao et al.   Cell Death & Disease

LncRNA MALAT1 promotes high glucose-induced inflammatory response of microglial cells via provoking MyD88/IRAK1/TRAF6 signaling

(2018) Li-Qing Wang et al.   Scientific Reports

Krüppel-like factor 4 (KLF4): What we currently know

(2017) Amr M. Ghaleb et al.   GENE

Long Noncoding RNA H19 Promotes Neuroinflammation in Ischemic Stroke by Driving Histone Deacetylase 1–Dependent M1 Microglial Polarization

(2017) Jue Wang et al.   STROKE

Krüppel-like factors and vascular wall homeostasis

(2017) Yanbo Fan et al.   Journal of Molecular Cell Biology

Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate ischemic neuronal death by targeting miR-21/PDCD4 signaling pathway

(2017) Honglin Yan et al.   Cell Death & Disease

Potential applications of MEG3 in cancer diagnosis and prognosis

(2017) Yuqing He et al.   Oncotarget

The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis

(2017) Jin Xu et al.   Cell and Bioscience

TREM2 protects against cerebral ischemia/reperfusion injury

(2017) Rong Wu et al.   Molecular Brain

Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury

(2016) Youguang Gao et al.   Molecular Medicine Reports

Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches

(2016) Julia Beermann et al.   PHYSIOLOGICAL REVIEWS

Revisiting Cerebral Postischemic Reperfusion Injury: New Insights in Understanding Reperfusion Failure, Hemorrhage, and Edema

(2015) Jilin Bai et al.   International Journal of Stroke

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

(2011) Carlo Perego et al.   Journal of Neuroinflammation

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Krüppel-like factor 4, a novel transcription factor regulates microglial activation and subsequent neuroinflammation

(2010) Deepak K Kaushik et al.   Journal of Neuroinflammation