Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

Biochemical insights from population studies with genetics and metabolomics

(2016) Karsten Suhre et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

(2016) Johannes Kettunen et al.   Nature Communications

Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes

(2015) Tove Fall et al.   DIABETES

Incretin-based therapies: where will we be 50 years from now?

(2015) Juris J. Meier et al.   DIABETOLOGIA

Genetics of human metabolism: an update

(2015) Gabi Kastenmüller et al.   HUMAN MOLECULAR GENETICS

Mendelian randomization: where are we now and where are we going?

(2015) S. Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice

(2015) Andreas Bickert et al.   JOURNAL OF LIPID RESEARCH

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

(2015) Daniel I Swerdlow et al.   LANCET

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Untargeted Metabolic Profiling Identifies Altered Serum Metabolites of Type 2 Diabetes Mellitus in a Prospective, Nested Case Control Study

(2014) D. Drogan et al.   CLINICAL CHEMISTRY

Pleiotropic Effects of Lipid Genes on Plasma Glucose, HbA1c, and HOMA-IR Levels

(2014) N. Li et al.   DIABETES

An atlas of genetic influences on human blood metabolites

(2014) So-Youn Shin et al.   NATURE GENETICS

Large-scale Metabolomic Profiling Identifies Novel Biomarkers for Incident Coronary Heart Disease

(2014) Andrea Ganna et al.   PLoS Genetics

Genome-Wide Association Study Identifies Novel Loci Associated With Concentrations of Four Plasma Phospholipid Fatty Acids in the De Novo Lipogenesis Pathway

(2013) Jason H.Y. Wu et al.   Circulation-Cardiovascular Genetics

Human Insulin Resistance Is Associated With Increased Plasma Levels of 12 -Hydroxylated Bile Acids

(2013) R. A. Haeusler et al.   DIABETES

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Risk Prediction Measures for Case-Cohort and Nested Case-Control Designs: An Application to Cardiovascular Disease

(2012) Andrea Ganna et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

(2012) A. Floegel et al.   DIABETES

Sphingosine 1-Phosphate (S1P) Regulates Glucose-stimulated Insulin Secretion in Pancreatic Beta Cells

(2012) Jamie Cantrell Stanford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel biomarkers for pre-diabetes identified by metabolomics

(2012) Rui Wang-Sattler et al.   Molecular Systems Biology

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Plasma Lysophosphatidylcholine Levels Are Reduced in Obesity and Type 2 Diabetes

(2012) Melissa N. Barber et al.   PLoS One

The Swedish Twin Registry: Establishment of a Biobank and Other Recent Developments

(2012) Patrik K. E. Magnusson et al.   Twin Research and Human Genetics

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

(2012) Ayşe Demirkan et al.   PLoS Genetics

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting

(2010) Karsten Suhre et al.   PLoS One