T-cell receptor repertoire variation may be associated with type 2 diabetes mellitus in humans

Autoimmune Aspects of Type 2 Diabetes Mellitus - A Mini-Review

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Human lymphocyte repertoires in ageing

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Immunosequencing: applications of immune repertoire deep sequencing

(2013) Harlan Robins   CURRENT OPINION IN IMMUNOLOGY

Islet autoimmunity in phenotypic type 2 diabetes patients

(2013) B. Brooks-Worrell et al.   DIABETES OBESITY & METABOLISM

High-Throughput Sequencing of Islet-Infiltrating Memory CD4+ T Cells Reveals a Similar Pattern of TCR Vβ Usage in Prediabetic and Diabetic NOD Mice

(2013) Idania Marrero et al.   PLoS One

Mechanisms of immunosenescence: lessons from models of accelerated immune aging

(2012) Sabine Le Saux et al.   Annals of the New York Academy of Sciences

Autoreactive Effector/Memory CD4+ and CD8+ T Cells Infiltrating Grafted and Endogenous Islets in Diabetic NOD Mice Exhibit Similar T Cell Receptor Usage

(2012) Ramiro Diz et al.   PLoS One

HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretion

(2011) R. C. Williams et al.   DIABETOLOGIA

Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions

(2011) B. D. Rudd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep Sequencing of the Human TCR  and TCR  Repertoires Suggests that TCR  Rearranges After    and    T Cell Commitment

(2011) A. M. Sherwood et al.   Science Translational Medicine

Identification of Autoantibody-Negative Autoimmune Type 2 Diabetic Patients

(2010) B. M. Brooks-Worrell et al.   DIABETES CARE

Genetics, pathogenesis and clinical interventions in type 1 diabetes

(2010) Jeffrey A. Bluestone et al.   NATURE

Overlap and Effective Size of the Human CD8+ T Cell Receptor Repertoire

(2010) H. S. Robins et al.   Science Translational Medicine

Comprehensive assessment of T-cell receptor  -chain diversity in    T cells

(2009) H. S. Robins et al.   BLOOD

Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients

(2009) Federico Serana et al.   Journal of Translational Medicine

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

Reappraising the stereotypes of diabetes in the modern diabetogenic environment

(2009) John M. Wentworth et al.   Nature Reviews Endocrinology