Dehydroxyhispolon Methyl Ether, A Hispolon Derivative, Inhibits WNT/β-Catenin Signaling to Elicit Human Colorectal Carcinoma Cell Apoptosis

Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling

(2020) Chi-Hung R. Or et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathways

(2020) Mao-lin Wan et al.   BIOSCIENCE REPORTS

Anticancer Perspectives of the Fungal-Derived Polyphenolic Hispolon

(2020) Muhammad T. Islam et al.   Anti-Cancer Agents in Medicinal Chemistry

Targeting β-Catenin Signaling by Natural Products for Cancer Prevention and Therapy

(2020) Wen-Kai Yu et al.   Frontiers in Pharmacology

A Review: The Bioactivities and Pharmacological Applications of Phellinus linteus

(2019) Chen et al.   MOLECULES

Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4′-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells

(2019) Yen-Po Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

Multiple Targets of the Canonical WNT/β-Catenin Signaling in Cancers

(2019) Yves Lecarpentier et al.   Frontiers in Oncology

Signaling pathways involved in colorectal cancer progression

(2019) Zahra Koveitypour et al.   Cell and Bioscience

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Dietary phytochemicals in colorectal cancer prevention and treatment: A focus on the molecular mechanisms involved

(2018) Sadia Afrin et al.   BIOTECHNOLOGY ADVANCES

Therapeutic potential of targeting the Wnt/β-catenin signaling pathway in colorectal cancer

(2018) Xiaofei Cheng et al.   BIOMEDICINE & PHARMACOTHERAPY

APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer

(2017) Noritaka Tanaka et al.   MOLECULAR CANCER THERAPEUTICS

Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells

(2017) Min-Chieh Hsin et al.   Cell Death & Disease

Design, synthesis and in vitro cell-based evaluation of the anti-cancer activities of hispolon analogs

(2015) Neduri V. Balaji et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer

(2015) Lukas E. Dow et al.   CELL

5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway

(2014) Dipon Das et al.   DNA REPAIR

Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages

(2014) Liang-Yo Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hispolon from Phellinus linteus Induces G0/G1 Cell Cycle Arrest and Apoptosis in NB4 Human Leukaemia Cells

(2013) Yi-Chuan Chen et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

BMI1 Polycomb Group Protein Acts as a Master Switch for Growth and Death of Tumor Cells: Regulates TCF4-Transcriptional Factor-Induced BCL2 Signaling

(2013) Hifzur Rahman Siddique et al.   PLoS One

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

(2012) Wenjun Guo et al.   CELL

Transcription Factor TCF4 Maintains the Properties of Human Corneal Epithelial Stem Cells

(2012) Rong Lu et al.   STEM CELLS

Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy

(2010) Te-Ling Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bisdemethylcurcumin and structurally related hispolon analogues of curcumin exhibit enhanced prooxidant, anti-proliferative and anti-inflammatory activities in vitro

(2010) Jayaraj Ravindran et al.   BIOCHEMICAL PHARMACOLOGY

 -Catenin Promotes Survival of Renal Epithelial Cells by Inhibiting Bax

(2009) Z. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prodigiosin down-regulates survivin to facilitate paclitaxel sensitization in human breast carcinoma cell lines

(2008) Tsing-Fen Ho et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY