The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice

Expression, Cellular and Subcellular Localisation of Kv4.2 and Kv4.3 Channels in the Rodent Hippocampus

(2019) Rocío Alfaro-Ruíz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epilepsy gene therapy using an engineered potassium channel

(2019) Albert Snowball et al.   JOURNAL OF NEUROSCIENCE

MicroRNA inhibition upregulates hippocampal A-type potassium current and reduces seizure frequency in a mouse model of epilepsy

(2019) Durgesh Tiwari et al.   NEUROBIOLOGY OF DISEASE

Isoform-selective phosphoinositide 3-kinase inhibition ameliorates a broad range of fragile X syndrome-associated deficits in a mouse model

(2018) Christina Gross et al.   NEUROPSYCHOPHARMACOLOGY

Reconciling the different faces of hippocampal theta: The role of theta oscillations in cognitive, emotional and innate behaviors

(2018) Tatiana Korotkova et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Kv4.2 autism and epilepsy mutation enhances inactivation of closed channels but impairs access to inactivated state after opening

(2018) Meng-chin A. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of Intercalated Cells (ITCs) in the Mouse Amygdala ofTshz1Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes

(2017) Jeffrey Kuerbitz et al.   JOURNAL OF NEUROSCIENCE

Electrocorticographic Dynamics as a Novel Biomarker in Five Models of Epileptogenesis

(2017) Dan Z. Milikovsky et al.   JOURNAL OF NEUROSCIENCE

Autism, epilepsy, and synaptopathies: a not rare association

(2017) Roberto Keller et al.   NEUROLOGICAL SCIENCES

Sensory processing in autism spectrum disorders and Fragile X syndrome—From the clinic to animal models

(2017) D. Sinclair et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model

(2017) Pascal Lösing et al.   Molecular Brain

Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism

(2017) Sameer C. Dhamne et al.   Molecular Autism

Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models

(2016) Verónica Martínez-Cerdeño   Developmental Neurobiology

Structural and functional plasticity of dendritic spines - root or result of behavior?

(2016) C. D. Gipson et al.   GENES BRAIN AND BEHAVIOR

MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset

(2016) Christina Gross et al.   Cell Reports

Tau-Dependent Kv4.2 Depletion and Dendritic Hyperexcitability in a Mouse Model of Alzheimer's Disease

(2015) Alicia M. Hall et al.   JOURNAL OF NEUROSCIENCE

Impermanence of dendritic spines in live adult CA1 hippocampus

(2015) Alessio Attardo et al.   NATURE

Immediate Epileptogenesis after Kainate-Induced Status Epilepticus in C57BL/6J Mice: Evidence from Long Term Continuous Video-EEG Telemetry

(2015) Sreekanth Puttachary et al.   PLoS One

Selective Role of the Catalytic PI3K Subunit p110β in Impaired Higher Order Cognition in Fragile X Syndrome

(2015) Christina Gross et al.   Cell Reports

Increased Expression of the PI3K Enhancer PIKE Mediates Deficits in Synaptic Plasticity and Behavior in Fragile X Syndrome

(2015) Christina Gross et al.   Cell Reports

Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

(2014) Bin Yang et al.   CELL

Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation

(2014) Hane Lee et al.   HUMAN MOLECULAR GENETICS

Advantages of Repeated Low Dose against Single High Dose of Kainate in C57BL/6J Mouse Model of Status Epilepticus: Behavioral and Electroencephalographic Studies

(2014) Karen Tse et al.   PLoS One

Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins

(2014) Joaquin N. Lugo et al.   Frontiers in Molecular Neuroscience

Loss of Functional A-Type Potassium Channels in the Dendrites of CA1 Pyramidal Neurons from a Mouse Model of Fragile X Syndrome

(2013) B. N. Routh et al.   JOURNAL OF NEUROSCIENCE

The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice

(2012) Milena Menegola et al.   EPILEPSIA

Dynamic Regulation of Synaptic Maturation State by Voltage-Gated A-Type K+ Channels in CA1 Hippocampal Pyramidal Neurons

(2012) E. Kim et al.   JOURNAL OF NEUROSCIENCE

Kv4.2 knockout mice have hippocampal-dependent learning and memory deficits

(2012) J. N. Lugo et al.   LEARNING & MEMORY

Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

(2012) Aditi Bhattacharya et al.   NEURON

Dendritic spine pathology in epilepsy: Cause or consequence?

(2012) M. Wong et al.   NEUROSCIENCE

Unique somato-dendritic distribution pattern of Kv4.2 channels on hippocampal CA1 pyramidal cells

(2011) Katalin Kerti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder

(2011) Jillian P. Casey et al.   HUMAN GENETICS

Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese

(2011) Youling Guo et al.   HUMAN MOLECULAR GENETICS

Reduced Spine Density in Specific Regions of CA1 Pyramidal Neurons in Two Transgenic Mouse Models of Alzheimer's Disease

(2011) C. Perez-Cruz et al.   JOURNAL OF NEUROSCIENCE

Fragile X Mental Retardation Protein Regulates Protein Expression and mRNA Translation of the Potassium Channel Kv4.2

(2011) C. Gross et al.   JOURNAL OF NEUROSCIENCE

Alterations of A-Type Potassium Channels in Hippocampal Neurons after Traumatic Brain Injury

(2011) Zhigang Lei et al.   JOURNAL OF NEUROTRAUMA

DPP6 Establishes the A-Type K+ Current Gradient Critical for the Regulation of Dendritic Excitability in CA1 Hippocampal Neurons

(2011) Wei Sun et al.   NEURON

Bidirectional Regulation of Dendritic Voltage-Gated Potassium Channels by the Fragile X Mental Retardation Protein

(2011) Hye Young Lee et al.   NEURON

Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels

(2011) Helene Vacher et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Molecular Dissection of IA in Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded by Kv4.2, Kv4.3, and Kv1.4  -Subunits

(2010) A. J. Norris et al.   JOURNAL OF NEUROSCIENCE

Interdependent Roles for Accessory KChIP2, KChIP3, and KChIP4 Subunits in the Generation of Kv4-Encoded IA Channels in Cortical Pyramidal Neurons

(2010) A. J. Norris et al.   JOURNAL OF NEUROSCIENCE

Arc regulates spine morphology and maintains network stability in vivo

(2010) C. L. Peebles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kv4.2 knockout mice demonstrate increased susceptibility to convulsant stimulation

(2009) L. Forbes S. Barnwell et al.   EPILEPSIA

EEG spike activity precedes epilepsy after kainate-induced status epilepticus

(2009) Andrew White et al.   EPILEPSIA

Widespread changes in dendritic and axonal morphology inMecp2-mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks

(2009) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Mouse plasmacytoma-expressed transcript 1 knock out induced 5-HT disruption results in a lack of cognitive deficits and an anxiety phenotype complicated by hypoactivity and defensiveness

(2009) T.L. Schaefer et al.   NEUROSCIENCE

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

(2009) Alexia Thomas et al.   PSYCHOPHARMACOLOGY

Applications of Lentiviral Vectors for Biology and Gene Therapy of Neurological Disorders

(2008) Cecilia Lundberg et al.   CURRENT GENE THERAPY

Kv4 Accessory Protein DPPX (DPP6) is a Critical Regulator of Membrane Excitability in Hippocampal CA1 Pyramidal Neurons

(2008) Jinhyun Kim et al.   JOURNAL OF NEUROPHYSIOLOGY

Altered synaptic and non-synaptic properties of CA1 pyramidal neurons in Kv4.2 knockout mice

(2008) B. K. Andrásfalvy et al.   JOURNAL OF PHYSIOLOGY-LONDON

Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy

(2008) M.M. Monaghan et al.   NEUROSCIENCE

Automated Three-Dimensional Detection and Shape Classification of Dendritic Spines from Fluorescence Microscopy Images

(2008) Alfredo Rodriguez et al.   PLoS One