Potent synthetic and endogenous ligands for the adopted orphan nuclear receptor Nurr1
出版年份 2021 全文链接
标题
Potent synthetic and endogenous ligands for the adopted orphan nuclear receptor Nurr1
作者
关键词
-
出版物
EXPERIMENTAL AND MOLECULAR MEDICINE
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-01-21
DOI
10.1038/s12276-021-00555-5
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception
- (2020) Yongwoo Jang et al. Journal of Neuroinflammation
- Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
- (2020) Eva Schrezenmeier et al. Nature Reviews Rheumatology
- Unraveling correlative roles of dopamine transporter (DAT) and Parkin in Parkinson’s disease (PD) – A road to discovery?
- (2020) Kaavya Jayaramayya et al. BRAIN RESEARCH BULLETIN
- PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function
- (2020) Sreekanth Rajan et al. Nature Chemical Biology
- Development of a novel NURR1/NOT agonist from hit to lead and candidate for the potential treatment of Parkinson's disease
- (2019) Dominique Lesuisse et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A Nurr1 agonist amodiaquine attenuates inflammatory events and neurological deficits in a mouse model of intracerebral hemorrhage
- (2019) Keita Kinoshita et al. JOURNAL OF NEUROIMMUNOLOGY
- Prostaglandin E2 as a potent therapeutic target for treatment of colon cancer
- (2019) Vahid Karpisheh et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Hydroxychloroquine antiparkinsonian potential: Nurr1 modulation versus autophagy inhibition
- (2019) Shireen A. Hedya et al. BEHAVIOURAL BRAIN RESEARCH
- Molecular, Chemical, and Structural Characterization of Prostaglandin A2 as a Novel Agonist for Nur77
- (2019) Sowmya P Lakshmi et al. BIOCHEMICAL JOURNAL
- New Insights into Malaria Pathogenesis
- (2019) Christopher A. Moxon et al. Annual Review of Pathology-Mechanisms of Disease
- Chloroquine modulates inflammatory autoimmune responses through Nurr1 in autoimmune diseases
- (2019) Tae-Yoon Park et al. Scientific Reports
- Nurr1 promotes neurogenesis of dopaminergic neuron and represses inflammatory factors in the transwell coculture system of neural stem cells and microglia
- (2018) Xiaoxiang Chen et al. CNS Neuroscience & Therapeutics
- Protective Effects of Hydroxychloroquine against Accelerated Atherosclerosis in Systemic Lupus Erythematosus
- (2018) Alberto Floris et al. MEDIATORS OF INFLAMMATION
- Nurr1 (NR4A2) regulates Alzheimer’s disease-related pathogenesis and cognitive function in the 5XFAD mouse model
- (2018) Minho Moon et al. AGING CELL
- Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1
- (2018) Ian Mitchelle S. de Vera et al. STRUCTURE
- Toward neuroprotective treatments of Parkinson’s disease
- (2017) Kwang-Soo Kim PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1
- (2016) Ian Mitchelle S. de Vera et al. ACS Chemical Biology
- Transcriptional modulation of regulatory T cell development by novel regulators NR4As
- (2016) Hee Yeon Won et al. ARCHIVES OF PHARMACAL RESEARCH
- Nurr1-Based Therapies for Parkinson's Disease
- (2016) Jie Dong et al. CNS Neuroscience & Therapeutics
- Nurr1 expression is modified by inflammation in microglia
- (2016) Scott W. Lallier et al. NEUROREPORT
- Hidroxicloroquina en el tratamiento de las enfermedades autoinmunes sistémicas
- (2016) Álvaro Danza et al. REVISTA MEDICA DE CHILE
- The Neuroprotective Role of Vesicular Monoamine Transporter 2 in Neurodegenerative Diseases
- (2015) Burak Yulug et al. Medicinal Chemistry
- Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s disease
- (2015) Chun-Hyung Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-genomic effects of the NR4A1/Nur77/TR3/NGFIB orphan nuclear receptor
- (2015) Alicja Pawlak et al. STEROIDS
- A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)
- (2015) Gaynor A. Smith et al. PLoS One
- Correlation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease
- (2014) Minho Moon et al. JOURNAL OF NEUROCHEMISTRY
- NR4A nuclear receptors in immunity and atherosclerosis
- (2013) Anouk A.J. Hamers et al. CURRENT OPINION IN LIPIDOLOGY
- Midbrain dopaminergic neurons: A review of the molecular circuitry that regulates their development
- (2013) Shane V. Hegarty et al. DEVELOPMENTAL BIOLOGY
- Ghrelin receptor is activated by naringin and naringenin, constituents of a prokinetic agent Poncirus fructus
- (2013) Yongwoo Jang et al. JOURNAL OF ETHNOPHARMACOLOGY
- NURR1 in Parkinson disease—from pathogenesis to therapeutic potential
- (2013) Mickael Decressac et al. Nature Reviews Neurology
- Naringin Exhibits in vivo Prokinetic Activity via Activation of Ghrelin Receptor in Gastrointestinal Motility Dysfunction Rats
- (2013) Yongwoo Jang et al. PHARMACOLOGY
- Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons
- (2013) B. Kadkhodaei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons
- (2012) M. Decressac et al. Science Translational Medicine
- Discovery of a Protein–Metabolite Interaction between Unsaturated Fatty Acids and the Nuclear Receptor Nur77 Using a Metabolomics Approach
- (2011) Nawaporn Vinayavekhin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells
- (2011) Takashi Sekiya et al. Nature Communications
- An aqueous extract of Poncirus fructus activates the prokinetic activity of 5-HT receptor subtype 4 without hERG interaction
- (2010) Won-Sik Shim et al. JOURNAL OF ETHNOPHARMACOLOGY
- NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
- (2010) N. Volakakis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death
- (2009) Kaoru Saijo et al. CELL
- Dopamine and the Dopamine Oxidation Product 5,6-Dihydroxylindole Promote Distinct On-Pathway and Off-Pathway Aggregation of α-Synuclein in a pH-Dependent Manner
- (2009) Chi L.L. Pham et al. JOURNAL OF MOLECULAR BIOLOGY
- Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress
- (2008) Emilce Carrasco et al. NEUROSCIENCE LETTERS
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