Article
Radiology, Nuclear Medicine & Medical Imaging
Clement Thomas, Mathieu Naudin, Jean-Pierre Tasu, Charles Leclerc, Lucas Depaire, Marie Subervillle, Mathilde Vionnet, Remy Guillevin, Guillaume Herpe
Summary: In a low prevalence area, chest CT scan is a valuable diagnostic tool for ruling out COVID-19 infection in symptomatic suspected patients.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Suji Lee, Young Joo Suh, Kyungsun Nam, Kyeho Lee, Hye-Jeong Lee, Byoung Wook Choi
Summary: Among the three artery-based ordinal grading methods, the length-based method is identified as the most reliable for evaluating coronary artery calcium on non-electrocardiogram (ECG)-gated low-dose chest computed tomography (LDCT), showing highest inter-observer agreement and agreement with ECG-gated calcium scoring CT.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ronald Booij, Marcel van Straten, Andreas Wimmer, Ricardo P. J. Budde
Summary: The study evaluated the impact of breathing state on the accuracy of a 3D camera for body contour detection and patient positioning in thoracic CT. Results showed that acquiring camera images and subsequent CT scans in the same breathing state leads to accurate and precise patient positioning. It is recommended to obtain expiratory planning images when performing a thoracic CT scan in both inspiratory and expiratory breathing states.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Inge A. H. H. van den Berk, Emile Lejeune, Maadrika M. N. P. Kanglie, Tjitske S. R. van Engelen, Wouter de Monye, Shandra Bipat, Patrick M. M. Bossuyt, Jaap M. Stoker, Jan Prins
Summary: The yield of ULDCT is higher than CXR in patients with suspected infection but without respiratory symptoms or signs. ULDCT has a higher sensitivity in detecting pneumonia compared to CXR.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Suh Young Kim, Young Joo Suh, Na Young Kim, Suji Lee, Kyungsun Nam, Jeongyun Kim, Hwan Kim, Hyunji Lee, Kyunghwa Han, Hwan Seok Yong
Summary: The study aimed to validate a simplified scoring method for assessing the severity of coronary artery calcium (CAC) on non-electrocardiogram (ECG)-gated chest computed tomography (CT). The modified length-based grading demonstrated better accuracy and consistency with cardiac CT results compared to visual assessment.
KOREAN JOURNAL OF RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ashish Verma, Ishan Kumar, Pramod Kumar Singh, Mohammad Sharoon Ansari, Harsh Anand Singh, Shashank Sonkar, Adity Prakash, Ritu Ojha, Ram Chandra Shukla
Summary: This study aims to compare the high-resolution CT scores between COVID-19 patients who received the SARS-CoV-2 vaccine and those who did not. The results show that individuals who received both doses of the vaccine had lower CT severity scores compared to those who received a single dose or no vaccine at all.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ivan Dudurych, Antonio Garcia-Uceda, Jens Petersen, Yihui Du, Rozemarijn Vliegenthart, Marleen de Bruijne
Summary: A deep learning and optimal-surface graph-cut method was developed to automatically segment the airway lumen and wall and calculate bronchial parameters. The reproducibility of this approach was evaluated on low-dose chest CT scans.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marie-Pierre Debray, Helena Tarabay, Lisa Males, Nisrine Chalhoub, Elyas Mahdjoub, Thomas Pavlovsky, Benoit Visseaux, Donia Bouzid, Raphael Borie, Catherine Wackenheim, Bruno Crestani, Christophe Rioux, Loukbi Saker, Christophe Choquet, Jimmy Mullaert, Antoine Khalil
Summary: The study assessed the interobserver agreement and clinical significance of chest CT reporting in patients suspected of COVID-19, showing good agreement between observers. Among patients suspected of COVID-19, CT categorized as evocative is highly predictive of COVID-19, while the predictive value decreases between the categories compatible and not evocative.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tingting Zhang, Xiao Li, Xiang Ji, Jianping Lu, Xu Fang, Yun Bian
Summary: The study investigated the association between longitudinal total pulmonary infection volume and volume ratio over time and clinical types in COVID-19 pneumonia patients. Propensity score analysis was used to match severe patients to moderate patients and balance baseline clinical and imaging variables. The results showed that total pulmonary infection volume and volume ratio were significantly associated with clinical types, with the severe group experiencing a higher increase over time compared to the moderate group.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Liang Li, Li Wang, Feifei Zeng, Gongling Peng, Zan Ke, Huan Liu, Yunfei Zha
Summary: A radiomics nomogram was developed and validated for timely prediction of severe COVID-19 pneumonia, showing good calibration and discrimination in training, validation, and testing cohorts. The CT-based radiomics model outperformed clinical factors and quantitative CT model alone in terms of discrimination capability and clinical usefulness, providing favorable predictive efficacy for severe COVID-19.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fides R. Schwartz, Francesco Ria, Cindy McCabe, Mojtaba Zarei, Jayasai Rajagopal, Lior Molvin, Daniele Marin, Bryan O'Sullivan-Murphy, Kevin R. Kalisz, Tina D. Tailor, Lacey Washington, Travis Henry, Ehsan Samei
Summary: This study compared the image quality between high-resolution, low-dose photon-counting detector CT (PCD-CT) and standard energy-integrating detector CT (EID) on the same patients. The results showed that PCD-CT had better subsegmental bronchial wall definition, higher noise, and overall image quality compared to EID. PCD-CT provided equivalent or better diagnostic quality at lower radiation doses, thanks to its improved resolution.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ozan Yar, Mehmet Ruhi Onur, Ilkay Sedakat Idilman, Erhan Akpinar, Deniz Akata
Summary: Over-scanning in z-axis is common in body CT examinations. Factors contributing to over-scanning include patient demographics, time, CT throughput, and technologist experience. Preventing over-scanning is important to reduce unnecessary radiation exposure in patients.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Caterina Beatrice Monti, Moreno Zanardo, Davide Capra, Gianluca Folco, Francesco Silletta, Francesco Secchi, Francesco Sardanelli
Summary: The study aims to evaluate myocardial status in COVID-19 patients through the assessment of extracellular volume (ECV) calculated at computed tomography (CT), with a focus on the presence of pulmonary embolism (PE) as a risk factor for cardiac dysfunction. The study retrospectively included hospitalized COVID-19 patients who underwent contrast-enhanced CT and divided them into groups based on the presence of PE. ECV values were calculated using unenhanced and portal venous phase scans, and correlations between ECV values and clinical or technical variables were analyzed.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Riken Chen, Huizhao Liao, Zhenan Deng, Zhenfeng He, Zhenzhen Zheng, Jianmin Lu, Mei Jiang, Xiaofeng Wu, Wenliang Guo, Zijie Huang, Huimin Chen, Cheng Hong, Nanshan Zhong
Summary: This study evaluates the diagnostic value of computed tomography (CT) in pulmonary hypertension. Through literature search and meta-analysis, it is found that CT examination of pulmonary artery diameter/aortic artery hypertension has good sensitivity and specificity and can be used in clinical applications.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ali H. Elmokadem, Ahmad M. Mounir, Zainab A. Ramadan, Mahmoud Elsedeiq, Gehad A. Saleh
Summary: This study compared the diagnostic performance and inter-observer agreement of different CT chest severity scoring systems for COVID-19, and found that CT-SS and TSS had the highest specificity and shortest interpretation time.
EUROPEAN RADIOLOGY
(2022)
Article
Clinical Neurology
Filippo Martinelli-Boneschi, Antonio Colombo, Nereo Bresolin, Maria Sessa, Pietro Bassi, Giampiero Grampa, Eugenio Magni, Maurizio Versino, Carlo Ferrarese, Davide Zarcone, Alberto Albanese, Giuseppe Micieli, Carla Zanferrari, Antonio Cagnana, Claudio Ferrante, Angelo Zilioli, Davide Locatelli, Maria Vittoria Calloni, Maria Luisa Delodovici, Mattia Pozzato, Valerio Patisso, Francesco Bortolan, Camillo Foresti, Barbara Frigeni, Stefania Canella, Rubjona Xhani, Massimo Crabbio, Alessandro Clemenzi, Marco Mauri, Simone Beretta, Isidoro La Spina, Simona Bernasconi, Tiziana De Santis, Anna Cavallini, Michela Ranieri, Elisabetta D'Adda, Maria Elisa Fruguglietti, Lorenzo Peverelli, Edoardo Agosti, Olivia Leoni, Andrea Rigamonti, Andrea Salmaggi
Summary: This study investigated the incidence, clinical characteristics, and outcomes of GBS in COVID-19 patients. The results showed an increased incidence of GBS in COVID-19 patients, suggesting a higher risk of GBS in individuals with COVID-19. Additionally, the study found a reduction in GBS events during the pandemic, which may be attributed to a decrease in the spread of more common respiratory infections.
NEUROLOGICAL SCIENCES
(2023)
Article
Acoustics
Anna Palmisano, Davide Vignale, Elisa Bruno, Giovanni Peretto, Giacomo De Luca, Corrado Campochiaro, Alessandro Tomelleri, Eustachio Agricola, Matteo Montorfano, Antonio Esposito
Summary: In this study, CMR findings in patients with myocarditis-like syndrome during the acute and post-acute phase of COVID-19 were reported. The majority of cases were confirmed as myocarditis by CMR, with mild extent of lesions. Additionally, some patients had myocardial infarction and cardiomyopathies. CMR can improve diagnostic accuracy and evaluate subclinical cardiomyopathies.
JOURNAL OF CLINICAL ULTRASOUND
(2023)
Article
Respiratory System
Eros Pilia, Alessandro Belletti, Stefano Fresilli, Todd C. Lee, Alberto Zangrillo, Gabriele Finco, Giovanni Landoni
Summary: This systematic review and meta-analysis aimed to evaluate the effect of full-dose heparin-based thromboprophylaxis on survival in hospitalized non-critically ill COVID-19 patients. The analysis showed that full-dose anticoagulation reduced all-cause mortality compared to prophylactic or intermediate dose anticoagulation. Therefore, full-dose anticoagulation can decrease all-cause mortality in hospitalized non-critically ill COVID-19 patients.
Correction
Clinical Neurology
Filippo Martinelli-Boneschi, Antonio Colombo, Nereo Bresolin, Maria Sessa, Pietro Bassi, Giampiero Grampa, Eugenio Magni, Maurizio Versino, Carlo Ferrarese, Davide Zarcone, Alberto Albanese, Giuseppe Micieli, Carla Zanferrari, Antonio Cagnana, Claudio Ferrante, Angelo Zilioli, Davide Locatelli, Maria Vittoria Calloni, Maria Luisa Delodovici, Mattia Pozzato, Valerio Patisso, Francesco Bortolan, Camillo Foresti, Barbara Frigeni, Stefania Canella, Rubjona Xhani, Massimo Crabbio, Alessandro Clemenzi, Marco Mauri, Simone Beretta, Isidoro La Spina, Simona Bernasconi, Tiziana De Santis, Anna Cavallini, Michela Ranieri, Elisabetta D'Adda, Maria Elisa Fruguglietti, Lorenzo Peverelli, Edoardo Agosti, Olivia Leoni, Andrea Rigamonti, Andrea Salmaggi
NEUROLOGICAL SCIENCES
(2023)
Article
Cardiac & Cardiovascular Systems
David Conen, Ekaterine Popova, Michael Ke Wang, Matthew T. V. Chan, Giovanni Landoni, Cara Reimer, Sadeesh K. Srinathan, Juan P. Cata, Sean R. McLean, Juan Carlos Trujillo Reyes, Ascension Martin Grande, Anna Gonzalez Tallada, Daniel I. Sessler, Edith Fleischmann, Donna E. Maziak, Barbara Kabon, Luca Voltolini, Laura Gutierrez-Soriano, Vikas Tandon, Deborah DuMerton, Biniam Kidane, Ravi Rajaram, Yaron Shargall, John D. Neary, Jennifer R. Wells, William F. McIntyre, Steffen Blum, Sandra N. Ofori, Jessica Vincent, Lizhen Xu, Zhuoru Li, Jeff S. Healey, Amit X. Garg, P. J. Devereaux
Summary: The COP-AF trial aims to test whether colchicine reduces the incidence of perioperative atrial fibrillation and myocardial injury after noncardiac surgery.
AMERICAN HEART JOURNAL
(2023)
Editorial Material
Anesthesiology
Yuki Kotani, Alessandro Belletti, Jacopo D'Andria Ursoleo, Stefano Salvati, Giovanni Landoni
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2023)
Letter
Geriatrics & Gerontology
Giacomo Maiucci, Stefano Fresilli, Giovanni Landoni
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Medicine, General & Internal
Ludhmila Abrahao Hajjar, Marco B. Ancona, Roberto Kalil Filho, Moreno Tresoldi, Jose Guilherme Caldas, Giacomo Monti, Francisco Cesar Carnevale, Francesco De Cobelli, Andre Moreira de Assis, Fabio Ciceri, Giovanni Landoni, Jouke Dijkstra, Francesco Moroni, Alexandre Antonio Cunha Abizaid, Fernanda Willemann Ungaretti, Maria Jose Carvalho Carmona, Daniel De Backer, Carlos Eduardo Pompilio, Fabio S. de Britto Jr, Carlos M. Campos, Alberto Zangrillo, Matteo Montorfano
Summary: This study aimed to evaluate the diagnostic value of optical coherence tomography (OCT) for pulmonary microvascular thromboinflammatory syndrome in patients with COVID-19 pneumonia. The results showed that OCT assessment of the distal pulmonary arteries in hospitalized COVID-19 patients is safe and accurate, enabling the first in vivo documentation of distal pulmonary arterial thrombosis in patients with elevated thromboinflammatory markers, even when their CT angiogram was negative for pulmonary thrombosis.
FRONTIERS IN MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Maria Lombardi, Marta Bonora, Luca Baldetti, Marina Pieri, Anna Mara Scandroglio, Giovanni Landoni, Alberto Zangrillo, Chiara Foglieni, Filippo Consolo
Summary: This study found significant differences in the expression levels of platelet miR-126, miR-374b, miR-223, and miR-320a between LVAD patients and healthy controls. The expression levels of platelet miR-25, miR-144, miR-320, and miR-451a changed significantly during LVAD support, and these miRs were implicated in cardiac- and coagulation-associated pathways. Patients who experienced bleeding had significantly higher expression levels of platelet miR-151a and miR-454 before LVAD implantation, and these miRs were also differentially expressed before the clinical manifestation of bleeding events. This study provides evidence of significant modulation of platelet miRs expression driven by LVADs and suggests the potential predictive value of platelet miRs in bleeding events.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, Research & Experimental
Giacomo Monti, Aidos Konkayev, Sonia Carta, Nikola Bradic, Andrea Bruni, Yuki Kotani, Fabio Guarracino, Ivan Redkin, Giuseppe Biondi-Zoccai, Umberto Benedetto, Fabrizio D'Ascenzo, Eugenio Garofalo, Martina Baiardo Redaelli, Giulia Brizzi, Francesco Forfori, Giovanni Borghi, Sara Scapol, Elena Momesso, Raffaele Cuffaro, Nicoletta Boffa, Simon Rauch, Filippo D'Amico, Giorgia Montrucchio, Maria Caterina Pace, Carola Galbiati, Stefano Bosso, Francesco Savelli, Giuseppe Giardina, Simona Silvetti, Vincenzo Francesco Tripodi, Rosa Labanca, Rosalba Lembo, Marilena Marmiere, Matteo Marzaroli, Cristina Nakhnoukh, Davide Valsecchi, Gabriele Finco, Felice Eugenio Agro, Tiziana Bove, Francesco Corradi, Federico Longhini, Giovanni Landoni, Rinaldo Bellomo, Alberto Zangrillo
Summary: This study aims to investigate the efficacy of high dose esomeprazole in reducing organ dysfunction in patients with sepsis or septic shock. Through a randomized trial, the study will compare the mean daily Sequential Organ Failure Assessment (SOFA) score over 10 days between the high dose esomeprazole group and the placebo group, as well as secondary outcomes such as antibiotic-free days, single organ failure severity, intensive care unit-free days at day 28, and mortality. The results of this study are expected to provide new insights for the treatment of sepsis or septic shock.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Critical Care Medicine
Yuki Kotani, Alessandro Pruna, Stefano Turi, Giovanni Borghi, Todd C. C. Lee, Alberto Zangrillo, Giovanni Landoni, Laura Pasin
Summary: This study conducted a systematic review and meta-analysis, and found that propofol may reduce survival in perioperative and critically ill patients compared to other hypnotic agents. Therefore, a careful assessment of the risk versus benefit of propofol compared to other agents is needed when planning for large, pragmatic multicentric randomized controlled trials to provide a definitive answer.
Letter
Critical Care Medicine
Yuki Kotani, Giovanni Landoni, Alessandro Belletti, Ashish K. Khanna
Article
Medicine, General & Internal
Giacomo Monti, Nikola Bradic, Matteo Marzaroli, Aidos Konkayev, Evgeny Fominskiy, Yuki Kotani, Valery V. Likhvantsev, Elena Momesso, Pavel Nogtev, Rosetta Lobreglio, Ivan Redkin, Fabio Toffoletto, Andrea Bruni, Martina Baiardo Redaelli, Natascia D'Andrea, Gianluca Paternoster, Anna Mara Scandroglio, Francesca Gallicchio, Mariano Ballestra, Maria Grazia Calabro, Antonella Cotoia, Romina Perone, Raffaele Cuffaro, Giorgia Montrucchio, Vincenzo Pota, Sofia Ananiadou, Rosalba Lembo, Mario Musu, Simon Rauch, Carola Galbiati, Fulvio Pinelli, Laura Pasin, Fabio Guarracino, Giuseppe Santarpino, Felice Eugenio Agro, Tiziana Bove, Francesco Corradi, Francesco Forfori, Federico Longhini, Maurizio Cecconi, Giovanni Landoni, Rinaldo Bellomo, Alberto Zangrillo
Summary: This double-blind, randomized clinical trial investigated the impact of continuous vs. intermittent administration of meropenem on the composite outcome of mortality and emergence of pandrug-resistant or extensively drug-resistant bacteria in critically ill patients. The results showed that continuous administration did not improve the primary outcome at day 28, and none of the secondary outcomes were statistically significant.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)