Anti-tubercular profile of new selenium-menadione conjugates against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain and multidrug-resistant clinical isolates

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

The Antifungal Activity of Naphthoquinones: An Integrative Review

(2018) DÉBORA O. FUTURO et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Drug-resistant tuberculosis: challenges and opportunities for diagnosis and treatment

(2018) Anastasia Koch et al.   CURRENT OPINION IN PHARMACOLOGY

Synthesis and evaluation of the cytotoxic activity of Furanaphthoquinones tethered to 1 H -1,2,3-triazoles in Caco-2, Calu-3, MDA-MB231 cells

(2018) Dora C.S. Costa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase

(2017) Xianling Ning et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti- Trypanosoma cruzi activities and electrochemical studies of functionalized quinones

(2017) Guilherme A.M. Jardim et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis

(2017) Bruno Couto Giacobbo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Selenium-Quinone Hybrid Compounds with Potential Antitumor Activity via Rh-Catalyzed C-H Bond Activation and Click Reactions

(2017) Guilherme Jardim et al.   MOLECULES

New agents for the treatment of drug-resistant Mycobacterium tuberculosis

(2016) Daniel T. Hoagland et al.   ADVANCED DRUG DELIVERY REVIEWS

Ebselen and analogs as inhibitors of Bacillus anthracis thioredoxin reductase and bactericidal antibacterials targeting Bacillus species, Staphylococcus aureus and Mycobacterium tuberculosis

(2016) Tomas N. Gustafsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Synthesis and evaluation of dihydropyrimidinone-derived selenoesters as multi-targeted directed compounds against Alzheimer’s disease

(2016) Flavio A.R. Barbosa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Natural Naphthoquinones with Great Importance in Medicinal Chemistry

(2016) Fernando de Carvalho da Silva et al.   CURRENT ORGANIC SYNTHESIS

Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights

(2016) Eduardo H.G. da Cruz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New family of antimicrobial agents derived from 1,4-naphthoquinone

(2016) Monika Janeczko et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

First case of extensively drug-resistant tuberculosis treated with both delamanid and bedaquiline

(2016) Marina Tadolini et al.   EUROPEAN RESPIRATORY JOURNAL

1,2-Benzisoselenazol-3(2H)-one Derivatives As a New Class of Bacterial Urease Inhibitors

(2016) Katarzyna Macegoniuk et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rh-Catalyzed Reactions of 1,4-Benzoquinones with Electrophiles: C–H Iodination, Bromination, and Phenylselenation

(2016) Guilherme A. M. Jardim et al.   ORGANIC LETTERS

eIF2 kinases mediate β-lapachone toxicity in yeast and human cancer cells

(2015) Mauricio Menacho-Márquez et al.   CELL CYCLE

Molecular descriptors calculation as a tool in the analysis of the antileishmanial activity achieved by two series of diselenide derivatives. An insight into its potential action mechanism

(2015) María Font et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

A Structure–Activity Relationship Study of Naphthoquinone Derivatives as Antitubercular Agents Using Molecular Modeling Techniques

(2015) Mukesh C. Sharma   Interdisciplinary Sciences-Computational Life Sciences

Multidrug-resistant tuberculosis around the world: what progress has been made?

(2014) D. Falzon et al.   EUROPEAN RESPIRATORY JOURNAL

Totally drug-resistant tuberculosis and adjunct therapies

(2014) S. K. Parida et al.   JOURNAL OF INTERNAL MEDICINE

Beyond Topoisomerase Inhibition: Antitumor 1,4-Naphthoquinones as Potential Inhibitors of Human Monoamine Oxidase

(2013) Eduardo Coelho-Cerqueira et al.   Chemical Biology & Drug Design

Advances in the development of new tuberculosis drugs and treatment regimens

(2013) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Naphthoquinones isolated from Diospyros anisandra exhibit potent activity against pan-resistant first-line drugs Mycobacterium tuberculosis strains

(2013) Andrés Humberto Uc-Cachón et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen

(2013) Lorenza Favrot et al.   Nature Communications

Catalytic application of selenium and tellurium compounds as glutathione peroxidase enzyme mimetics

(2011) Eduardo E Alberto et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

In vitro antifungal evaluation and structure-activity relationship of diphenyl diselenide and synthetic analogues

(2011) Érico Silva Loreto et al.   MYCOSES

Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants

(2010) Krishna P. Bhabak et al.   ACCOUNTS OF CHEMICAL RESEARCH

Selenium- and Tellurium-Containing Multifunctional Redox Agents as Biochemical Redox Modulators with Selective Cytotoxicity

(2010) Vincent Jamier et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Selective Anticancer Activity of Organochalcogen Based Redox Catalysts

(2010) Mandy Doering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery

(2010) Sean Ekins et al.   TRENDS IN MICROBIOLOGY

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing multifunctional redox agents

(2009) Susanne Mecklenburg et al.   ORGANIC & BIOMOLECULAR CHEMISTRY