Antibacterial activities with the structure-activity relationship of coumarin derivatives

Radical scavenging and anti-inflammatory activities of (hetero)arylethenesulfonyl fluorides: Synthesis and structure-activity relationship (SAR) and QSAR studies

(2019) Ying Jiang et al.   BIOORGANIC CHEMISTRY

Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review

(2019) Wan-Yin Fang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Monocarbonyl Curcumin-Based Molecular Hybrids as Potent Antibacterial Agents

(2019) Atamjit Singh et al.   ACS Omega

Amino acids conjugated quinazolinone-Schiff’s bases as potential antimicrobial agents: Synthesis, SAR and molecular docking studies

(2019) K.P. Rakesh et al.   BIOORGANIC CHEMISTRY

Chalcone derivatives and their antibacterial activities: Current development

(2019) Man Xu et al.   BIOORGANIC CHEMISTRY

Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents

(2019) Hao Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Amino acids/peptides conjugated heterocycles: A tool for the recent development of novel therapeutic agents

(2018) Meng Wang et al.   BIOORGANIC CHEMISTRY

Molecular docking studies and facile synthesis of most potent biologically active N - tert -butyl-4-(4-substituted phenyl)-2-((substituted-2-oxo-2H-chromen-4-yl)methylthio)-6-oxo-1,6-dihydropyrimidine-5-carboxamide hybrids: An approach for microwave-assisted syntheses and biological evaluation

(2018) Rakesh R. Chavan et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of coumarin derivatives containing imidazole skeleton as potential antibacterial agents

(2018) Yang Hu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of coumarin clubbed thiazines scaffolds as antimicrobial and antioxidant

(2018) Nilesh B. Chauhan et al.   MEDICINAL CHEMISTRY RESEARCH

Vision for medicine: Staphylococcus aureus biofilm war and unlocking key's for anti-biofilm drug development

(2018) H.M. Manukumar et al.   MICROBIAL PATHOGENESIS

Role of BP*C@AgNPs in Bap-dependent multicellular behavior of clinically important methicillin-resistant Staphylococcus aureus (MRSA) biofilm adherence: A key virulence study

(2018) Zhang Xu et al.   MICROBIAL PATHOGENESIS

Master mechanisms of Staphylococcus aureus : consider its excellent protective mechanisms hindering vaccine development!

(2018) Xu Zhang et al.   MICROBIOLOGICAL RESEARCH

Synthesis and Antimicrobial Activity of 4-Substituted 1,2,3-Triazole-Coumarin Derivatives

(2018) Priscila López-Rojas et al.   MOLECULES

Promising bactericidal approach of dihydrazone analogues against bio-film forming Gram-negative bacteria and molecular mechanistic studies

(2018) K. P. Rakesh et al.   RSC Advances

1,2,3-Triazole fused with pyridine/pyrimidine as new template for antimicrobial agents: Regioselective synthesis and identification of potent N-heteroarenes

(2018) Nagaraju Marepu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Aryl fluorosulfate analogues as potent antimicrobial agents: SAR, cytotoxicity and docking studies

(2018) Lekkala Ravindar et al.   BIOORGANIC CHEMISTRY

Multi-targeted dihydrazones as potent biotherapeutics

(2018) Chen Li et al.   BIOORGANIC CHEMISTRY

Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives

(2018) N.S. El-Gohary et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections

(2018) Gao-Feng Zha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review

(2018) Chuang Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Combating a Master Manipulator: Staphylococcus aureus Immunomodulatory Molecules as Targets for Combinatorial Drug Discovery

(2018) Kadalipura P. Rakesh et al.   ACS Combinatorial Science

Antibacterial activity and mechanism of action of the benzazole acrylonitrile-based compounds: In vitro , spectroscopic, and docking studies

(2017) Shaikha S. AlNeyadi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and molecular docking studies of substituted 4-coumarinylpyrano[2,3-c]pyrazole derivatives as potent antibacterial and anti-inflammatory agents

(2017) Bahubali M. Chougala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and molecular docking studies of xanthone attached amino acids as potential antimicrobial and anti-inflammatory agents

(2017) Xing Chen et al.   MedChemComm

Benzisoxazole: a privileged scaffold for medicinal chemistry

(2017) K. P. Rakesh et al.   MedChemComm

Novel T-C@AgNPs mediated biocidal mechanism against biofilm associated methicillin-resistant Staphylococcus aureus (Bap-MRSA) 090, cytotoxicity and its molecular docking studies

(2017) H. M. Manukumar et al.   MedChemComm

Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole–coumarin hybrids

(2016) Tatjana Gazivoda Kraljević et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of antimicrobial, anticoagulant, and anticholinesterase hybrid molecules from 4-methylumbelliferone

(2016) Marwa Zayane et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular docking of novel coumarin incorporated triazoles as antitubercular, antioxidant and antimicrobial agents

(2016) Mubarak H. Shaikh et al.   MEDICINAL CHEMISTRY RESEARCH

Design and synthesis of coumarin–glyoxal hybrids for spermicidal and antimicrobial actions: a dual approach to contraception

(2016) Swati Gupta et al.   RSC Advances

Schiff’s bases of quinazolinone derivatives: Synthesis and SAR studies of a novel series of potential anti-inflammatory and antioxidants

(2015) K.P. Rakesh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cardiovascular Effects of Coumarins Besides their Antioxidant Activity

(2015) Iveta Najmanova et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Current developments of coumarin-based anti-cancer agents in medicinal chemistry

(2015) Saeed Emami et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent progress in the drug development of coumarin derivatives as potent antituberculosis agents

(2015) Rangappa S. Keri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

(2015) Anuradha Thakur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Benzofuran as a promising scaffold for the synthesis of antimicrobial and antibreast cancer agents: A review

(2015) Ghadamali Khodarahmi et al.   Journal of Research in Medical Sciences

Synthesis, anti-microbial and anti-cancer evaluation study of 3-(3-benzofuranyl)-coumarin derivatives

(2015) Bahubali M. Chougala et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of novel 4-hydroxycoumarin derivatives: evaluation of antimicrobial, antioxidant activities and its molecular docking studies

(2015) M. Govindhan et al.   MEDICINAL CHEMISTRY RESEARCH

3-(1-Phenyl-4-((2-(4-arylthiazol-2-yl)hydrazono)methyl)-1H-pyrazol-3-yl)-2H-chromen-2-ones: one-pot three component condensation, in vitro antimicrobial, antioxidant and molecular docking studies

(2015) Ramesh Gondru et al.   RSC Advances

Design and synthesis of novel 2H-chromen-2-one derivatives bearing 1,2,3-triazole moiety as lead antimicrobials

(2014) Khushbu Kushwaha et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New Insights into the Chemistry and Antioxidant Activity of Coumarins

(2014) Fernando Torres et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Microwave-assisted synthesis of (E)-7-[(1-benzyl-1H-1,2,3-triazol-4-yl)methoxy]-8-(3-arylacryloyl)-4-methyl-2H-chromen-2-ones and their antimicrobial activity

(2014) Ashok Dongamanti et al.   HETEROCYCLIC COMMUNICATIONS

An efficient synthesis and antimicrobial screening of new hybrid molecules containing coumarin and indenopyridine moiety

(2014) Dinkar I. Brahmbhatt et al.   MEDICINAL CHEMISTRY RESEARCH

Design, synthesis and antidepressant activities of some novel fatty acid analogues

(2014) Selvaraj Jubie et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, biological evaluation and docking studies of 4-aryloxymethyl coumarins derived from substructures and degradation products of vancomycin

(2013) Hrishikesh M. Revankar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and pharmacological evaluation of some novel 2-(5-hydroxy-5-trifluoromethyl-4,5-dihydropyrazol-1-yl)-4-(coumarin-3-yl)thiazoles

(2013) Ranjana Aggarwal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Microwave assisted synthesis of dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones; synthesis, in vitro antimicrobial and anticancer activities of novel coumarin substituted dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones

(2013) Kallimeledoddi B. Puttaraju et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antimicrobial Activities of Some Triazole, Thiadiazole, and Oxadiazole Substituted Coumarins

(2013) K. Rajasekhar Reddy et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Four-Component Domino Strategy for the Combinatorial Synthesis of Novel 1,4-Dihydropyrano[2,3-c]pyrazol-6-amines

(2013) Selvaraj Kanchithalaivan et al.   ACS Combinatorial Science

Synthesis of Novel Quinolone and Coumarin Based 1,3,4-Thiadiazolyl and 1,3,4-Oxadiazolyl N-Mannich Bases as Potential Antimicrobials

(2012) Rahul V. Patel et al.   LETTERS IN ORGANIC CHEMISTRY

Coumarin: a potential nucleus for anti-inflammatory molecules

(2012) Yogita Bansal et al.   MEDICINAL CHEMISTRY RESEARCH

Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitors

(2011) Yunqi Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A review on coumarins as acetylcholinesterase inhibitors for Alzheimer’s disease

(2011) Preet Anand et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of some 4-functionalized-pyrazoles as antimicrobial agents

(2011) Pawan K. Sharma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, pharmacological evaluation and docking studies of coumarin derivatives

(2011) B. Sandhya et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel 1,2,5-trisubstituted benzimidazoles as potential antitumor agents

(2011) Rodrigo Abonia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Tackling antibiotic resistance

(2011) Karen Bush et al.   NATURE REVIEWS MICROBIOLOGY

Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents

(2010) Yuan Shi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Coumarins: Old Compounds with Novel Promising Therapeutic Perspectives

(2010) M. Riveiro et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities

(2010) Nermien M. Sabry et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimicrobial activity of 7-(2-substituted phenylthiazolidinyl)-benzopyran-2-one derivatives

(2009) Pradeepkumar M. Ronad et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimicrobial studies on novel sulfonamides containing 4-azidomethyl coumarin

(2009) Mahantesha Basanagouda et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, spectroscopic and antibacterial investigations of new hydroxy ethers and heterocyclic coumarin derivatives

(2009) Naceur Hamdi et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis and antimicrobial screening of N-[coumarin-6-yl-amino] thiazolidinone and its derivatives

(2009) Vinata V. Mulwad et al.   JOURNAL OF CHEMICAL RESEARCH

Synthesis and Antimicrobial Evaluation of Some Novel 2‐Aminothiazole Derivatives of 4‐Hydroxy‐chromene‐2‐one

(2008) Nenad Vukovic et al.   ARCHIV DER PHARMAZIE