Fumonisins B1 exposure triggers intestinal tract injury via activating nuclear xenobiotic receptors and attracting inflammation response

Cadmium exposure induces apoptosis, inflammation and immunosuppression through CYPs activation and antioxidant dysfunction in common carp neutrophils

(2020) Sun Jiaxin et al.   FISH & SHELLFISH IMMUNOLOGY

Bisphenol A regulates cytochrome P450 1B1 through miR-27b-3p and induces carp lymphocyte oxidative stress leading to apoptosis

(2020) Qingqing Liu et al.   FISH & SHELLFISH IMMUNOLOGY

Phytic Acid Decreases Oxidative Stress and Intestinal Lesions Induced by Fumonisin B1 and Deoxynivalenol in Intestinal Explants of Pigs

(2019) Elisângela da Silva et al.   Toxins

Pregnane X Receptor Activation Triggers Rapid ATP Release in Primed Macrophages That Mediates NLRP3 Inflammasome Activation

(2019) Grace Hudson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Aflatoxin B1 promotes autophagy associated with oxidative stress-related PI3K/AKT/mTOR signaling pathway in mice testis

(2019) Wanyue Huang et al.   ENVIRONMENTAL POLLUTION

Cytochrome P450 Structure, Function and Clinical Significance: A Review

(2018) Palrasu Manikandan et al.   CURRENT DRUG TARGETS

Mycotoxins induce developmental toxicity and behavioural aberrations in zebrafish larvae

(2018) Abdolrahman Khezri et al.   ENVIRONMENTAL POLLUTION

The Role of the Aryl Hydrocarbon Receptor (AHR) in Immune and Inflammatory Diseases

(2018) Drew Neavin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prevention of Oxidative Stress by α-Ketoglutarate via Activation of CAR Signaling and Modulation of the Expression of Key Antioxidant-Associated Targets in Vivo and in Vitro

(2018) Liuqin He et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A novel nuclear xenobiotic receptors (AhR/PXR/CAR)-mediated mechanism of DEHP-induced cerebellar toxicity in quails ( Coturnix japonica ) via disrupting CYP enzyme system homeostasis

(2017) Zheng-Hai Du et al.   ENVIRONMENTAL POLLUTION

CAR: A key regulator of adhesion and inflammation

(2017) Elena Ortiz-Zapater et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Susceptibility of Broiler Chickens to Coccidiosis When Fed Subclinical Doses of Deoxynivalenol and Fumonisins—Special Emphasis on the Immunological Response and the Mycotoxin Interaction

(2016) Bertrand Grenier et al.   Toxins

Effects of aflatoxin B1, fumonisin B1 and their mixture on the aryl hydrocarbon receptor and cytochrome P450 1A induction

(2015) Verónica S. Mary et al.   FOOD AND CHEMICAL TOXICOLOGY

Individual and combined effects of Fusarium toxins on the mRNA expression of pro-inflammatory cytokines in swine jejunal epithelial cells

(2013) Lam-Yim Murphy Wan et al.   TOXICOLOGY LETTERS

Murine atrial HL-1 cell line is a reliable model to study drug metabolizing enzymes in the heart

(2012) Osama H. Elshenawy et al.   VASCULAR PHARMACOLOGY

Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene

(2011) Lucie Krausova et al.   BIOCHEMICAL PHARMACOLOGY

Chronic ingestion of deoxynivalenol and fumonisin, alone or in interaction, induces morphological and immunological changes in the intestine of piglets

(2011) Ana-Paula F. L. Bracarense et al.   BRITISH JOURNAL OF NUTRITION

The mycotoxin, patulin, increases the expression of PXR and AhR and their target cytochrome P450s in primary cultured human hepatocytes

(2011) Imen Ayed-Boussema et al.   DRUG AND CHEMICAL TOXICOLOGY

Effect of Aflatoxin B1 on Nuclear Receptors PXR, CAR, and AhR and Their Target Cytochromes P450 mRNA Expression in Primary Cultures of Human Hepatocytes

(2011) Imen Ayed-Boussema et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Zearalenone activates pregnane X receptor, constitutive androstane receptor and aryl hydrocarbon receptor and corresponding phase I target genes mRNA in primary cultures of human hepatocytes

(2010) Imen Ayed-Boussema et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY