Integrin signalling regulates YAP and TAZ to control skin homeostasis

Alternative Wnt Signaling Activates YAP/TAZ

(2015) Hyun Woo Park et al.   CELL

Zyxin Antagonizes the FERM Protein Expanded to Couple F-Actin and Yorkie-Dependent Organ Growth

(2015) Pedro Gaspar et al.   CURRENT BIOLOGY

Yap and Taz are required for Ret-dependent urinary tract morphogenesis

(2015) Antoine Reginensi et al.   DEVELOPMENT

Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap

(2015) Aleksander D. Szymaniak et al.   DEVELOPMENTAL CELL

The Spectrin cytoskeleton regulates the Hippo signalling pathway

(2015) G. C. Fletcher et al.   EMBO JOURNAL

β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis

(2015) Jing Cai et al.   GENES & DEVELOPMENT

Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway

(2015) Nam-Gyun Kim et al.   JOURNAL OF CELL BIOLOGY

YAPing Hippo Forecasts a New Target for Lung Cancer Prevention and Treatment

(2015) Duojia Pan   JOURNAL OF CLINICAL ONCOLOGY

A gp130–Src–YAP module links inflammation to epithelial regeneration

(2015) Koji Taniguchi et al.   NATURE

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

Mechanical strain induces E-cadherin-dependent Yap1 and  -catenin activation to drive cell cycle entry

(2015) B. W. Benham-Pyle et al.   SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Control of Organ Growth by Patterning and Hippo Signaling inDrosophila

(2015) Kenneth D. Irvine et al.   Cold Spring Harbor Perspectives in Biology

Localization of Hippo signalling complexes and Warts activation in vivo

(2015) Shuguo Sun et al.   Nature Communications

MicroRNA-135b Promotes Cancer Progression by Acting as a Downstream Effector of Oncogenic Pathways in Colon Cancer

(2014) Nicola Valeri et al.   CANCER CELL

Cytoskeletal Tension Inhibits Hippo Signaling through an Ajuba-Warts Complex

(2014) Cordelia Rauskolb et al.   CELL

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

Crosstalk between Epithelial and Mesenchymal Tissues in Tumorigenesis and Imaginal Disc Development

(2014) Héctor Herranz et al.   CURRENT BIOLOGY

Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo

(2014) Shihadeh Anani et al.   DEVELOPMENT

Inhibition of RHO–ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst

(2014) Kanako Kono et al.   DEVELOPMENTAL BIOLOGY

Yap Tunes Airway Epithelial Size and Architecture by Regulating the Identity, Maintenance, and Self-Renewal of Stem Cells

(2014) Rui Zhao et al.   DEVELOPMENTAL CELL

A Molecular Switch for the Orientation of Epithelial Cell Polarization

(2014) David M. Bryant et al.   DEVELOPMENTAL CELL

c-Src drives intestinal regeneration and transformation

(2014) J. B. Cordero et al.   EMBO JOURNAL

Metabolic control of YAP and TAZ by the mevalonate pathway

(2014) Giovanni Sorrentino et al.   NATURE CELL BIOLOGY

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine

(2014) A Kohlmaier et al.   ONCOGENE

Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2

(2013) Feng Yin et al.   CELL

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

Molecular Pathways: YAP and TAZ Take Center Stage in Organ Growth and Tumorigenesis

(2013) S. Piccolo et al.   CLINICAL CANCER RESEARCH

Mask Is Required for the Activity of the Hippo Pathway Effector Yki/YAP

(2013) Leticia Sansores-Garcia et al.   CURRENT BIOLOGY

Mask Proteins Are Cofactors of Yorkie/YAP in the Hippo Pathway

(2013) Clara M. Sidor et al.   CURRENT BIOLOGY

Integrin signaling is required for maintenance and proliferation of intestinal stem cells in Drosophila

(2013) Guonan Lin et al.   DEVELOPMENTAL BIOLOGY

The Hippo Effector Yorkie Controls Normal Tissue Growth by Antagonizing Scalloped-Mediated Default Repression

(2013) Laura M. Koontz et al.   DEVELOPMENTAL CELL

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

(2013) F.-X. Yu et al.   GENES & DEVELOPMENT

Dasatinib inhibits mammary tumour development in a genetically engineered mouse model

(2013) Saadia A Karim et al.   JOURNAL OF PATHOLOGY

A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway

(2013) Morvarid Mohseni et al.   NATURE CELL BIOLOGY

Riquiqui and Minibrain are regulators of the Hippo pathway downstream of Dachsous

(2013) Joffrey L. Degoutin et al.   NATURE CELL BIOLOGY

Drosophila actin-Capping Protein limits JNK activation by the Src proto-oncogene

(2013) B G Fernández et al.   ONCOGENE

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

(2013) R. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide Association of Yorkie with Chromatin and Chromatin-Remodeling Complexes

(2013) Hyangyee Oh et al.   Cell Reports

Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling

(2013) Yunyun Jin et al.   eLife

Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells

(2012) Rachel A. Ridgway et al.   CARCINOGENESIS

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

Mutual Repression by Bantam miRNA and Capicua Links the EGFR/MAPK and Hippo Pathways in Growth Control

(2012) Héctor Herranz et al.   CURRENT BIOLOGY

Positive Feedback and Mutual Antagonism Combine to Polarize Crumbs in the Drosophila Follicle Cell Epithelium

(2012) Georgina C. Fletcher et al.   CURRENT BIOLOGY

Cell polarity: models and mechanisms from yeast, worms and flies

(2012) B. J. Thompson   DEVELOPMENT

Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP

(2012) Katrin Straßburger et al.   DEVELOPMENTAL BIOLOGY

Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila

(2012) Masato Enomoto et al.   EMBO REPORTS

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)

(2012) J.-S. Mo et al.   GENES & DEVELOPMENT

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex

(2012) Ahmed Elbediwy et al.   JOURNAL OF CELL BIOLOGY

An integrin–ILK–microtubule network orients cell polarity and lumen formation in glandular epithelium

(2012) Nasreen Akhtar et al.   NATURE CELL BIOLOGY

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

(2011) Karen Doggett et al.   BMC DEVELOPMENTAL BIOLOGY

Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation

(2011) Karin Schlegelmilch et al.   CELL

Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador–Warts–Hippo pathway

(2011) X Zhang et al.   CELL DEATH AND DIFFERENTIATION

Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila

(2011) B. G. Fernandez et al.   DEVELOPMENT

EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells

(2011) Na Xu et al.   DEVELOPMENTAL BIOLOGY

Modulating F-actin organization induces organ growth by affecting the Hippo pathway

(2011) Leticia Sansores-Garcia et al.   EMBO JOURNAL

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model

(2011) M Willecke et al.   ONCOGENE

Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis

(2011) R. Marcotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

(2011) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zyxin Links Fat Signaling to the Hippo Pathway

(2011) Cordelia Rauskolb et al.   PLOS BIOLOGY

EGFR/Ras/MAPK Signaling Mediates Adult Midgut Epithelial Homeostasis and Regeneration in Drosophila

(2010) Huaqi Jiang et al.   Cell Stem Cell

Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell Proliferation

(2010) Binnaz Kucuk Staley et al.   CURRENT BIOLOGY

Ajuba LIM Proteins Are Negative Regulators of the Hippo Signaling Pathway

(2010) Meghna Das Thakur et al.   CURRENT BIOLOGY

The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration

(2010) R. L. Shaw et al.   DEVELOPMENT

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

The WW Domain Protein Kibra Acts Upstream of Hippo in Drosophila

(2010) Roland Baumgartner et al.   DEVELOPMENTAL CELL

Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded

(2010) Jianzhong Yu et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network

(2010) Alice Genevet et al.   DEVELOPMENTAL CELL

Dasatinib Inhibits the Development of Metastases in a Mouse Model of Pancreatic Ductal Adenocarcinoma

(2010) Jennifer P. Morton et al.   GASTROENTEROLOGY

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

(2010) J. Cai et al.   GENES & DEVELOPMENT

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded

(2010) C. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila

(2010) C.-L. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Creation of an antibody-based subcellular protein atlas

(2010) Emma Lundberg et al.   PROTEOMICS

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

β1 Integrin-Mediated Adhesion Signalling Is Essential for Epidermal Progenitor Cell Expansion

(2009) Aleksandra Piwko-Czuchra et al.   PLoS One

A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model

(2008) Bryan Serrels et al.   CARCINOGENESIS

In vivo regulation of Yorkie phosphorylation and localization

(2008) H. Oh et al.   DEVELOPMENT

The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway

(2008) Shian Wu et al.   DEVELOPMENTAL CELL

Loss of Integrin α9β1 Results in Defects in Proliferation, Causing Poor Re-Epithelialization during Cutaneous Wound Healing

(2008) Purva Singh et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Human Protein Atlas-a tool for pathology

(2008) F Pontén et al.   JOURNAL OF PATHOLOGY

A Genecentric Human Protein Atlas for Expression Profiles Based on Antibodies

(2008) Lisa Berglund et al.   MOLECULAR & CELLULAR PROTEOMICS