The catalytic mechanism of sulfoxide synthases

Structural basis of ergothioneine biosynthesis

(2020) Anja R Stampfli et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

An Alternative Active Site Architecture for O2 Activation in the Ergothioneine Biosynthetic EgtB from Chloracidobacterium thermophilum

(2019) Anja R. Stampfli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Substrate Specificity in Thiol Dioxygenases

(2019) Sekotilani Aloi et al.   BIOCHEMISTRY

Selenocysteine as a substrate, an inhibitor and a mechanistic probe for bacterial and fungal iron‐dependent sulfoxide synthases.

(2019) Kristina V. Goncharenko et al.   CHEMISTRY-A EUROPEAN JOURNAL

Biosynthetic Pathways to Nonproteinogenic α-Amino Acids

(2019) Jason B. Hedges et al.   CHEMICAL REVIEWS

Spectroscopic and Computational Comparisons of Thiolate-Ligated Ferric Nonheme Complexes to Cysteine Dioxygenase: Second-Sphere Effects on Substrate (Analogue) Positioning

(2019) Anne A. Fischer et al.   INORGANIC CHEMISTRY

Role of Ergothioneine in Microbial Physiology and Pathogenesis

(2018) Bridgette M. Cumming et al.   ANTIOXIDANTS & REDOX SIGNALING

Mini-Review: Ergothioneine and Ovothiol Biosyntheses, an Unprecedented Trans-Sulfur Strategy in Natural Product Biosynthesis

(2018) Nathchar Naowarojna et al.   BIOCHEMISTRY

Ergothioneine - a diet-derived antioxidant with therapeutic potential

(2018) Barry Halliwell et al.   FEBS LETTERS

Use of a Tyrosine Analogue To Modulate the Two Activities of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis, Cysteine Oxidation versus Oxidative C–S Bond Formation

(2018) Li Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of Sulfoxidation and C–S Bond Formation Involved in the Biosynthesis of Ergothioneine Catalyzed by Ergothioneine Synthase (EgtB)

(2018) Ge Tian et al.   ACS Catalysis

A Reversible and Repeatable Thiol–Ene Bioconjugation for Dynamic Patterning of Signaling Proteins in Hydrogels

(2018) Joseph C. Grim et al.   ACS Central Science

Biosynthesis and isolation of selenoneine from genetically modified fission yeast

(2018) Nikolaus G. Turrini et al.   Metallomics

On ovothiol biosynthesis and biological roles: from life in the ocean to therapeutic potential

(2018) Immacolata Castellano et al.   NATURAL PRODUCT REPORTS

In Vitro Reconstitution of the Remaining Steps in Ovothiol A Biosynthesis: C–S Lyase and Methyltransferase Reactions

(2018) Nathchar Naowarojna et al.   ORGANIC LETTERS

Spectroscopic and Electronic Structure Study of ETHE1: Elucidating the Factors Influencing Sulfur Oxidation and Oxygenation in Mononuclear Nonheme Iron Enzymes

(2018) Serra Goudarzi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structures, Spectroscopic Properties, and Dioxygen Reactivity of 5- and 6-Coordinate Nonheme Iron(II) Complexes: A Combined Enzyme/Model Study of Thiol Dioxygenases

(2018) Jesse B. Gordon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prolonging healthy aging: Longevity vitamins and proteins

(2018) Bruce N. Ames   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic Studies of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis Using a Tyrosine Analogue, 2-Amino-3-(4-hydroxy-3-(methoxyl) phenyl) Propanoic Acid (MeOTyr)

(2018) Li Chen et al.   ACS Catalysis

Theoretical Study of the Mechanism of the Nonheme Iron Enzyme EgtB

(2017) Wen-Jie Wei et al.   INORGANIC CHEMISTRY

Ergothioneine Antioxidant Function

(2017) Luigi Servillo et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Sulfoxide Synthase versus Cysteine Dioxygenase Reactivity in a Nonheme Iron Enzyme

(2017) Abayomi S. Faponle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conversion of a non-heme iron-dependent sulfoxide synthase into a thiol dioxygenase by a single point mutation

(2016) Kristina V. Goncharenko et al.   CHEMICAL COMMUNICATIONS

Go it alone: four-electron oxidations by mononuclear non-heme iron enzymes

(2016) Spencer C. Peck et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Spectroscopic Evidence for the Two C–H-Cleaving Intermediates of Aspergillus nidulans Isopenicillin N Synthase

(2016) Esta Tamanaha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway

(2015) Kristina V. Goncharenko et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC

(2015) Allegra Vit et al.   CHEMBIOCHEM

Mechanistic studies of a novel C-S lyase in ergothioneine biosynthesis: the involvement of a sulfenic acid intermediate

(2015) Heng Song et al.   Scientific Reports

Cysteine Oxidation Reactions Catalyzed by a Mononuclear Non-heme Iron Enzyme (OvoA) in Ovothiol Biosynthesis

(2014) Heng Song et al.   ORGANIC LETTERS

Genetic and Metabolomic Dissection of the Ergothioneine and Selenoneine Biosynthetic Pathway in the Fission Yeast, S. pombe, and Construction of an Overproduction System

(2014) Tomáš Pluskal et al.   PLoS One

Substrate specificity of an oxygen dependent sulfoxide synthase in ovothiol biosynthesis

(2013) Gabriel T. M. Mashabela et al.   CHEMICAL COMMUNICATIONS

Regioselectivity of the Oxidative C–S Bond Formation in Ergothioneine and Ovothiol Biosyntheses

(2013) Heng Song et al.   ORGANIC LETTERS

Identification and Characterization of the First Ovothiol Biosynthetic Enzyme

(2011) Andrea Braunshausen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Substrate activation by iron superoxo intermediates

(2010) Wilfred A van der Donk et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

In Vitro Reconstitution of Mycobacterial Ergothioneine Biosynthesis

(2010) Florian P. Seebeck   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY