Article
Microbiology
Bradly Burke, Savannah M. Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A. Charley, Juergen A. Richt, Susan R. Weiss, Ronald B. Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz
Summary: Insectivorous Old World horseshoe bats are the likely source of SARS-CoV-2, and natural coronavirus infections in bats are mainly confined to the intestines. Jamaican fruit bats are poorly susceptible to SARS-CoV-2, but expression of human ACE2 in their lungs leads to robust infection and an adaptive immune response.
Article
Multidisciplinary Sciences
Marinda Mortlock, Marike Geldenhuys, Muriel Dietrich, Jonathan H. Epstein, Jacqueline Weyer, Janusz T. Paweska, Wanda Markotter
Summary: A study in southern Africa has identified 18 putative viral species circulating in a local bat population, with three showing differing seasonal dynamics, and winter and spring posing a higher risk of virus spillover and transmission. The annual peaks in virus excretion are likely driven by subadults and may be linked to the waning of maternal immunity and recolonization of the roost in early spring. These findings provide important insights into the bat-host relationship and can be applied to other populations across Africa for evidence-based public health education and prevention measures against pathogen spillover threats.
SCIENTIFIC REPORTS
(2021)
Article
Virology
Anitha D. D. Jayaprakash, Adam J. J. Ronk, Abhishek N. N. Prasad, Michael F. F. Covington, Kathryn R. R. Stein, Toni M. M. Schwarz, Saboor Hekmaty, Karla A. A. Fenton, Thomas W. W. Geisbert, Christopher F. F. Basler, Alexander Bukreyev, Ravi Sachidanandam
Summary: Filoviruses cause severe diseases in humans and nonhuman primates but have subclinical effects in bats. By infecting Egyptian rousette bats with Marburg and Ebola viruses, researchers identified various immune responses and pathways involved in bat resistance to these viruses, providing insights for the development of new strategies to treat and mitigate the diseases caused by these viruses in humans.
Article
Multidisciplinary Sciences
Aaron T. Irving, Matae Ahn, Geraldine Goh, Danielle E. Anderson, Lin-Fa Wang
Summary: Recent outbreaks of emerging viral diseases have been linked to suspected zoonotic transmission of bat-borne viruses. Bats display unique biological characteristics shaped by millions of years of adaptive evolution. Understanding the mechanisms of immune tolerance in bats could help improve human health.
Article
Public, Environmental & Occupational Health
Diego Cantoni, Martin Mayora-Neto, Mariliza Derveni, Kelly Da Costa, Joanne Del Rosario, Veronica O. Ameh, Claude T. Sabeta, Bethany Auld, Arran Hamlet, Ian M. Jones, Edward Wright, Simon D. Scott, Efstathios S. Giotis, Ashley C. Banyard, Nigel Temperton
Summary: This study conducted a serological survey of E. helvum fruit bats captured in Makurdi, Nigeria, and found neutralizing antibodies against known pathogenic viruses in these bats. These findings suggest a potential risk of zoonotic spillover from E. helvum fruit bats.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Immunology
Luiz Gustavo Bentim Goes, Carlo Fischer, Angelica Cristine Almeida Campos, Cristiano de Carvalho, Andres Moreira-Soto, Guilherme Ambar, Adriana Ruckert da Rosa, Debora Cardoso de Oliveira, Wendy Karen Jo, Ariovaldo P. Cruz-Neto, Wagner Andre Pedro, Luzia Helena Queiroz, Paola Minoprio, Edison L. Durigon, Jan Felix Drexler
Summary: This study detected arenavirus RNA in bats in Brazil and identified two new arenavirus species, highlighting the importance of bats as underrecognized reservoirs for these viruses.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Virology
Said Mougari, Claudia Gonzalez, Olivier Reynard, Branka Horvat
Summary: Bats serve as natural hosts for many zoonotic viruses and have evolved mechanisms to tolerate and control viral infections, preventing both virus expansion and excessive immune response.
CURRENT OPINION IN VIROLOGY
(2022)
Article
Multidisciplinary Sciences
Amy J. Schuh, Brian R. Amman, Jonathan C. Guito, James C. Graziano, Tara K. Sealy, Shannon G. M. Kirejczyk, Jonathan S. Towner
Summary: This study demonstrates that Egyptian rousette bats (ERBs) are natural vertebrate hosts for Kasokero virus (KASV) and can sustain viremias of appropriate magnitude and duration, supporting virus maintenance through bat-tick-bat transmission cycles. The results also suggest the potential for bat-to-bat transmission and spillover of KASV to humans through contact with infectious oral secretions, feces, or urine.
SCIENTIFIC REPORTS
(2022)
Article
Virology
Marcel Bokelmann, Uwe Vogel, Franka Debeljak, Ariane Duex, Silke Riesle-Sbarbaro, Angelika Lander, Annette Wahlbrink, Nicole Kromarek, Stuart Neil, Emmanuel Couacy-Hymann, Joseph Prescott, Andreas Kurth
Summary: Recent studies suggest that the Angolan free-tailed bat may be a possible reservoir for Ebola virus, with bat cells showing high tolerance and the virus's ability to persist without mutation for up to 150 days. This provides further evidence for the role of this bat species as a likely reservoir for ebolaviruses.
Article
Cell Biology
Peter A. Larson, Maggie L. Bartlett, Karla Garcia, Joseph Chitty, Anne Balkema-Buschmann, Jonathan Towner, Jeffrey Kugelman, Gustavo Palacios, Mariano Sanchez-Lockhart
Summary: The Egyptian rousette bat (ERB) is the only known reservoir for Marburgviruses and Sosuga virus, making it an exceptional animal model for studying antiviral mechanisms in an asymptomatic host. The study found expansions in immunoglobulin variable genes associated with protective human antibodies to different viruses in the ERB, as well as distinctive immunoglobulin epsilon and gamma genes. Additionally, the lack of evolutionary conserved short pentraxins in ERBs may promote tolerance and decrease inflammation.
Article
Immunology
Wenguang Cao, Shihua He, Guodong Liu, Helene Schulz, Karla Emeterio, Michael Chan, Kevin Tierney, Kim Azaransky, Geoff Soule, Nikesh Tailor, Abdjeleel Salawudeen, Rick Nichols, Joan Fusco, David Safronetz, Logan Banadyga
Summary: Recombinant vesicular stomatitis viruses (rVSVs) expressing viral glycoproteins have proven to be effective vaccines. An rVSV-based vaccine expressing the SUDV glycoprotein (rVSV-SUDV) shows promising results in protecting guinea pigs from SUDV disease and death. Surprisingly, rVSV-EBOV also provides limited protection against SUDV.
Article
Mathematics, Interdisciplinary Applications
Nan Zhang, Emmanuel Addai, Lingling Zhang, Mercy Ngungu, Edmore Marinda, Joshua Kiddy K. Asamoah
Summary: This paper investigates a deterministic mathematical model of Marburg-Monkeypox virus co-infection transmission. The dynamics behavior of the model is discussed and qualitative and quantitative analysis is conducted, including positivity-boundedness of solution and the basic reproduction number Ro. The existence-uniqueness of the solution in the suggested model is explored using Banach and Schauder-type fixed point theorem, and the stability of the proposed model under the Ulam-Hyers condition is demonstrated. Numerical simulation using Predictor-Corrector method is performed to determine the numerical solutions. The results suggest that increasing the rate of quarantine and detecting unknown Marburg virus are the most effective control interventions to reduce Marburg and Monkeypox virus transmission in the population.
FRACTALS-COMPLEX GEOMETRY PATTERNS AND SCALING IN NATURE AND SOCIETY
(2023)
Review
Microbiology
Manuel Ruiz-Aravena, Clifton McKee, Amandine Gamble, Tamika Lunn, Aaron Morris, Celine E. Snedden, Claude Kwe Yinda, Julia R. Port, David W. Buchholz, Yao Yu Yeo, Christina Faust, Elinor Jax, Lauren Dee, Devin N. Jones, Maureen K. Kessler, Caylee Falvo, Daniel Crowley, Nita Bharti, Cara E. Brook, Hector C. Aguilar, Alison J. Peel, Olivier Restif, Tony Schountz, Colin R. Parrish, Emily S. Gurley, James O. Lloyd-Smith, Peter J. Hudson, Vincent J. Munster, Raina K. Plowright
Summary: Bats are known to carry a variety of coronaviruses and have been identified as prime reservoir hosts for emerging viruses. Since the first SARS epidemic in 2002, the understanding of bats as key hosts of coronaviruses has rapidly advanced. There are critical knowledge gaps regarding bat coronaviruses, and filling these gaps may help prevent the next pandemic.
NATURE REVIEWS MICROBIOLOGY
(2022)
Article
Biology
Heidi K. Goethert, Thomas N. Mather, Richard W. Johnson, Sam R. I. I. I. I. I. I. Telford
Summary: The study revealed that shrews are likely a reservoir host for deer tick virus, instead of white-footed mice as previously thought, and that the virus is primarily transmitted through ticks. This finding is crucial for enhancing our understanding of the ecology of tick-borne infections.
COMMUNICATIONS BIOLOGY
(2021)
Review
Biology
Natalie Weber, Martina Nagy, Wanda Markotter, Juliane Schaer, Sebastien J. Puechmaille, Jack Sutton, Liliana M. Davalos, Marie-Claire Dusabe, Imran Ejotre, M. Brock Fenton, Mirjam Knoernschild, Adria Lopez-Baucells, Rodrigo A. Medellin, Markus Metz, Samira Mubareka, Olivier Nsengimana, M. Teague O'Mara, Paul A. Racey, Merlin Tuttle, Innocent Twizeyimana, Amanda Vicente-Santos, Marco Tschapka, Christian C. Voigt, Martin Wikelski, Dina K. N. Dechmann, DeeAnn M. Reeder
Summary: This study reviewed the research on African bats and their role as hosts for viruses causing human diseases. The impact of scientific research communication on public perception was discussed, and recommendations were made to improve study metadata.
Article
Virology
Yingyun Cai, Shuiqing Yu, Ying Fang, Laura Bollinger, Yanhua Li, Michael Lauck, Elena N. Postnikova, Steven Mazur, Reed F. Johnson, Courtney L. Finch, Sheli R. Radoshitzky, Gustavo Palacios, Thomas C. Friedrich, Tony L. Goldberg, David H. O'Connor, Peter B. Jahrling, Jens H. Kuhn
Summary: The study developed an infectious clone of SHFV for rapid detection of infection and demonstrated the replication of SHFV in different cell lines, providing important tools and insights for the molecular biology research of SHFV.
Article
Cell Biology
Peter A. Larson, Maggie L. Bartlett, Karla Garcia, Joseph Chitty, Anne Balkema-Buschmann, Jonathan Towner, Jeffrey Kugelman, Gustavo Palacios, Mariano Sanchez-Lockhart
Summary: The Egyptian rousette bat (ERB) is the only known reservoir for Marburgviruses and Sosuga virus, making it an exceptional animal model for studying antiviral mechanisms in an asymptomatic host. The study found expansions in immunoglobulin variable genes associated with protective human antibodies to different viruses in the ERB, as well as distinctive immunoglobulin epsilon and gamma genes. Additionally, the lack of evolutionary conserved short pentraxins in ERBs may promote tolerance and decrease inflammation.
Article
Virology
Jens H. Kuhn, Scott Adkins, Bernard R. Agwanda, Rim Al Kubrusli, Sergey V. Alkhovsky, Gaya K. Amarasinghe, Tatjana Avsic-Zupanc, Maria A. Ayllon, Justin Bahl, Anne Balkema-Buschmann, Matthew J. Ballinger, Christopher F. Basler, Sina Bavari, Martin Beer, Nicolas Bejerman, Andrew J. Bennett, Dennis A. Bente, Eric Bergeron, Brian H. Bird, Carol D. Blair, Kim R. Blasdell, Dag-Ragnar Blystad, Jamie Bojko, Wayne B. Borth, Steven Bradfute, Rachel Breyta, Thomas Briese, Paul A. Brown, Judith K. Brown, Ursula J. Buchholz, Michael J. Buchmeier, Alexander Bukreyev, Felicity Burt, Carmen Buettner, Charles H. Calisher, Mengji Cao, Inmaculada Casas, Kartik Chandran, Remi N. Charrel, Qi Cheng, Yuya Chiaki, Marco Chiapello, Il-Ryong Choi, Marina Ciuffo, J. Christopher S. Clegg, Ian Crozier, Elena Dal Bo, Juan Carlos de la Torre, Xavier de Lamballerie, Rik L. de Swart, Humberto Debat, Nolwenn M. Dheilly, Emiliano Di Cicco, Nicholas Di Paola, Francesco Di Serio, Ralf G. Dietzgen, Michele Digiaro, Olga Dolnik, Michael A. Drebot, J. Felix Drexler, William G. Dundon, W. Paul Duprex, Ralf Durrwald, John M. Dye, Andrew J. Easton, Hideki Ebihara, Toufic Elbeaino, Koray Ergunay, Hugh W. Ferguson, Anthony R. Fooks, Marco Forgia, Pierre B. H. Formenty, Jana Franova, Juliana Freitas-Astua, Jingjing Fu, Stephanie Fuerl, Selma Gago-Zachert, George Fu Gao, Maria Laura Garcia, Adolfo Garcia-Sastre, Aura R. Garrison, Thomas Gaskin, Jean-Paul J. Gonzalez, Anthony Griffiths, Tony L. Goldberg, Martin H. Groschup, Stephan Guenther, Roy A. Hall, John Hammond, Tong Han, Jussi Hepojoki, Roger Hewson, Jiang Hong, Ni Hong, Seiji Hongo, Masayuki Horie, John S. Hu, Tao Hu, Holly R. Hughes, Florian Huettner, Timothy H. Hyndman, M. Ilyas, Risto Jalkanen, Daohong Jiang, Gilda B. Jonson, Sandra Junglen, Fujio Kadono, Karia H. Kaukinen, Michael Kawate, Boris Klempa, Jonas Klingstrom, Gary Kobinger, Igor Koloniuk, Hideki Kondo, Eugene V. Koonin, Mart Krupovic, Kenji Kubota, Gael Kurath, Lies Laenen, Amy J. Lambert, Stanley L. Langevin, Benhur Lee, Elliot J. Lefkowitz, Eric M. Leroy, Shaorong Li, Longhui Li, Jianrong Li, Huazhen Liu, Igor S. Lukashevich, Pie Maes, William Marciel de Souza, Marco Marklewitz, Sergio H. Marshall, Shin-Yi L. Marzano, Sebastien Massart, John W. McCauley, Michael Melzer, Nicole Mielke-Ehret, Kristina M. Miller, Tobi J. Ming, Ali Mirazimi, Gideon J. Mordecai, Hans-Peter Muehlbach, Elke Muehlberger, Rayapati Naidu, Tomohide Natsuaki, Jose A. Navarro, Sergey V. Netesov, Gabriele Neumann, Norbert Nowotny, Marcio R. T. Nunes, Alejandro Olmedo-Velarde, Gustavo Palacios, Vicente Pallas, Bernadett Palyi, Anna Papa, Sofia Paraskevopoulou, Adam C. Park, Colin R. Parrish, David A. Patterson, Alex Pauvolid-Correa, Janusz T. Paweska, Susan Payne, Carlotta Peracchio, Daniel R. Perez, Thomas S. Postler, Liying Qi, Sheli R. Radoshitzky, Renato O. Resende, Carina A. Reyes, Bertus K. Rima, Gabriel Robles Luna, Victor Romanowski, Paul Rota, Dennis Rubbenstroth, Luisa Rubino, Jonathan A. Runstadler, Sead Sabanadzovic, Amadou Alpha Sall, Maria S. Salvato, Rosemary Sang, Takahide Sasaya, Angela D. Schulze, Martin Schwemmle, Mang Shi, Xiaohong Shi, Zhengli Shi, Yoshifumi Shimomoto, Yukio Shirako, Stuart G. Siddell, Peter Simmonds, Manuela Sironi, Guy Smagghe, Sophie Smither, Jin-Won Song, Kirsten Spann, Jessica R. Spengler, Mark D. Stenglein, David M. Stone, Jari Sugano, Curtis A. Suttle, Amy Tabata, Ayato Takada, Shigeharu Takeuchi, David P. Tchouassi, Amy Teffer, Robert B. Tesh, Natalie J. Thornburg, Yasuhiro Tomitaka, Keizo Tomonaga, Noel Tordo, Baldwyn Torto, Jonathan S. Towner, Shinya Tsuda, Changchun Tu, Massimo Turina, Ioannis E. Tzanetakis, Janice Uchida, Tomio Usugi, Anna Maria Vaira, Marta Vallino, Bernadette van den Hoogen, Arvind Varsani, Nikos Vasilakis, Martin Verbeek, Susanne von Bargen, Jiro Wada, Victoria Wahl, Peter J. Walker, Lin-Fa Wang, Guoping Wang, Yanxiang Wang, Yaqin Wang, Muhammad Waqas, Taiyun Wei, Shaohua Wen, Anna E. Whitfield, John V. Williams, Yuri I. Wolf, Jiangxiang Wu, Lei Xu, Hironobu Yanagisawa, Caixia Yang, Zuokun Yang, F. Murilo Zerbini, Lifeng Zhai, Yong-Zhen Zhang, Song Zhang, Jinguo Zhang, Zhe Zhang, Xueping Zhou
Summary: In March 2021, the phylum Negarnaviricota was amended and expanded by four families, three subfamilies, 42 genera, and 200 species. Additionally, 39 species were renamed or moved, and seven species were abolished. This article presents the updated taxonomy of Negarnaviricota accepted by the ICTV.
ARCHIVES OF VIROLOGY
(2021)
Article
Cell Biology
Jun Liu, John C. Trefry, April M. Babka, Christopher W. Schellhase, Kayla M. Coffin, Janice A. Williams, Jo Lynne W. Raymond, Paul R. Facemire, Taylor B. Chance, Neil M. Davis, Jennifer L. Scruggs, Franco D. Rossi, Andrew D. Haddow, Justine M. Zelko, Sandra L. Bixler, Ian Crozier, Patrick L. Iversen, Margaret L. Pitt, Jens H. Kuhn, Gustavo Palacios, Xiankun Zeng
Summary: Persistent Ebola virus infection in the brain ventricular system can occur in macaque survivors after therapeutic treatment, leading to severe tissue damage and inflammation.
SCIENCE TRANSLATIONAL MEDICINE
(2022)
Article
Medicine, General & Internal
Ayelen Alumine Iglesias, Natalia Periolo, Carla Maria Bellomo, Lorena Cecilia Lewis, Camila Paula Olivera, Constanza Rosario Anselmo, Marina Garcia, Rocio Maria Coelho, Daniel Oscar Alonso, Bonnie Dighero-Kemp, Heema Sharma, Jens H. Kuhn, Nicholas Di Paola, Mariano Sanchez-Lockhart, Gustavo Palacios, Luis Pablo Schierloh, Valeria Paula Martinez
Summary: This study found that the levels of activated CD4+ and CD8(+) T cells were increased in HPS patients, independent of disease severity. Higher levels of certain proinflammatory mediators were observed during the acute phase, but viral clearance was more closely related to high titers of neutralizing antibodies.
Article
Biotechnology & Applied Microbiology
Anna Papa, Marco Marklewitz, Sofia Paraskevopoulou, Aura R. Garrison, Sergey Alkhovsky, Tatjana Avsic-Zupanc, Dennis A. Bente, Eric Bergeron, Felicity Burt, Nicholas Di Paola, Koray Ergunay, Roger Hewson, Ali Mirazimi, Amadou Alpha Sall, Jessica R. Spengler, Thomas S. Postler, Gustavo Palacios, Jens H. Kuhn
Summary: Crimean-Congo haemorrhagic fever virus (CCHFV), the most medically significant member of the bunyaviral family Nairoviridae, has traditionally been grouped into six genotypes. However, the recent decision by the Nairoviridae Study Group of the International Committee on Taxonomy of Viruses (ICTV) re-classified genogroup VI as a distinct virus, Aigai virus (AIGV).
JOURNAL OF GENERAL VIROLOGY
(2022)
Article
Biochemistry & Molecular Biology
Lay Teng Ang, Alana T. Nguyen, Kevin J. Liu, Angela Chen, Xiaochen Xiong, Matthew Curtis, Renata M. Martin, Brian C. Raftry, Chun Yi Ng, Uwe Vogel, Angelika Lander, Benjamin J. Lesch, Jonas L. Fowler, Alyssa R. Holman, Timothy Chai, Siva Vijayakumar, Fabian P. Suchy, Toshinobu Nishimura, Joydeep Bhadury, Matthew H. Porteus, Hiromitsu Nakauchi, Christine Cheung, Steven C. George, Kristy Red-Horse, Joseph B. Prescott, Kyle M. Loh
Summary: This study successfully generated >90% pure human artery or vein endothelial cells from pluripotent stem cells within 3-4 days and used them to investigate the infection and effects of Nipah and Hendra viruses on arteries. They found that these viruses preferentially infected arteries, which expressed higher levels of the viral-entry receptor. Virally infected artery cells quickly fused into syncytia containing multiple nuclei, but rapidly died. However, these viruses largely evaded innate immune detection and minimally elicited interferon signaling during artery infection.
Article
Infectious Diseases
Eva Orviz, Anabel Negredo, Oskar Ayerdi, Ana Vazquez, Ana Munoz-Gomez, Sara Monzon, Petunia Clavo, Angel Zaballos, Mar Vera, Patricia Sanchez, Noemi Cabello, Pilar Jimenez, Jorge A. Perez-Garcia, Sarai Varona, Jorge del Romero, Isabel Cuesta, Alberto Delgado-Iribarren, Montse Torres, Inigo Sagastagoitia, Gustavo Palacios, Vicente Estrada, Maria Paz Sanchez-Seco
Summary: This observational study focused on monkeypox cases in Madrid, Spain, and investigated the clinical and virological aspects of the disease. The findings revealed that the virus circulating in Spain belongs to the western African clade, mainly affecting cisgender men who have sex with men (MSM). The first symptom of the disease was skin lesions, and the disease followed a self-limited course.
JOURNAL OF INFECTION
(2022)
Article
Virology
Alberto Paniz-Mondolfi, Susana Guerra, Marina Munoz, Nicolas Luna, Matthew M. Hernandez, Luz H. Patino, Jason Reidy, Radhika Banu, Paras Shrestha, Bernadette Liggayu, Audrey Umeaku, Feng Chen, Liyong Cao, Armi Patel, Ayman Hanna, Sunny Li, Andy Look, Nina Pagani, Randy Albrecht, Rebecca Pearl, Adolfo Garcia-Sastre, Dusan Bogunovic, Gustavo Palacios, Lucia Bonnier, Freddy Cera, Heidi Lopez, Yvette Calderon, Erick Eiting, Karr Mullen, Sangyoon Jason Shin, Luz Amarilis Lugo, Antonio E. Urbina, Carlotta Starks, Tonny Koo, Patricia Uychiat, Avery Look, Harm van Bakel, Ana Gonzalez-Reiche, Adolfo Firpo Betancourt, David Reich, Carlos Cordon-Cardo, Viviana Simon, Emilia M. Sordillo, Juan David Ramirez
Summary: Monkeypox virus is a zoonotic orthopoxvirus that is prevalent in Central and West Africa. A new real-time PCR assay for diagnosing MPXV infection in humans has been developed and validated, showing high specificity and sensitivity. The assay has been approved for clinical use by the NYS Department of Health.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Virology
Jens H. Kuhn, Scott Adkins, Sergey Alkhovsky, Tatjana Avsic-Zupanc, Maria A. Ayllon, Justin Bahl, Anne Balkema-Buschmann, Matthew J. Ballinger, Martina Bandte, Martin Beer, Nicolas Bejerman, Eric Bergeron, Nadine Biedenkopf, Laurent Bigarre, Carol D. Blair, Kim R. Blasdell, Steven B. Bradfute, Thomas Briese, Paul A. Brown, Remy Bruggmann, Ursula J. Buchholz, Michael J. Buchmeier, Alexander Bukreyev, Felicity Burt, Carmen Buettner, Charles H. Calisher, Thierry Candresse, Jeremy Carson, Inmaculada Casas, Kartik Chandran, Remi N. Charrel, Yuya Chiaki, Anya Crane, Mark Crane, Laurent Dacheux, Elena Dal Bo, Juan Carlos de la Torre, Xavier de Lamballerie, William M. de Souza, Rik L. de Swart, Nolwenn M. Dheilly, Nicholas Di Paola, Francesco Di Serio, Ralf G. Dietzgen, Michele Digiaro, J. Felix Drexler, W. Paul Duprex, Ralf Duerrwald, Andrew J. Easton, Toufc Elbeaino, Koray Ergunay, Guozhong Feng, Claudette Feuvrier, Andrew E. Firth, Anthony R. Fooks, Pierre B. H. Formenty, Juliana Freitas-Astua, Selma Gago-Zachert, Maria Laura Garcia, Adolfo Garcia-Sastre, Aura R. Garrison, Scott E. Godwin, Jean-Paul J. Gonzalez, Joelle Gouy de Bellocq, Anthony Grifths, Martin H. Groschup, Stephan Gunther, John Hammond, Jussi Hepojoki, Melanie M. Hierweger, Seiji Hongo, Masayuki Horie, Hidenori Horikawa, Holly R. Hughes, Adam J. Hume, Timothy H. Hyndman, Daohong Jiang, Gilda B. Jonson, Sandra Junglen, Fujio Kadono, David G. Karlin, Boris Klempa, Jonas Klingstrom, Michel C. Koch, Hideki Kondo, Eugene Koonin, Jarmila Krasova, Mart Krupovic, Kenji Kubota, Ivan Kuzmin, Lies Laenen, Amy J. Lambert, Jianrong Li, Jun-Min Li, Francois Liefrig, Igor S. Lukashevich, Dongsheng Luo, Piet Maes, Marco Marklewitz, Sergio H. Marshall, Shin-Yi L. Marzano, John W. McCauley, Ali Mirazimi, Peter G. Mohr, Nick J. G. Moody, Yasuaki Morita, Richard N. Morrison, Elke Muhlberger, Rayapati Naidu, Tomohide Natsuaki, Jose A. Navarro, Yutaro Neriya, Sergey Netesov, Gabriele Neumann, Norbert Nowotny, Francisco M. Ochoa-Corona, Gustavo Palacios, Laurane Pallandre, Vicente Pallas, Anna Papa, Sofa Paraskevopoulou, Colin R. Parrish, Alex Pauvolid-Correa, Janusz T. Paweska, Daniel R. Perez, Florian Pfaf, Richard K. Plemper, Thomas S. Postler, Francoise Pozet, Sheli R. Radoshitzky, Pedro L. Ramos-Gonzalez, Marius Rehanek, Renato O. Resende, Carina A. Reyes, Victor Romanowski, Dennis Rubbenstroth, Luisa Rubino, Artemis Rumbou, Jonathan A. Runstadler, Melanie Rupp, Sead Sabanadzovic, Takahide Sasaya, Heike Schmidt-Posthaus, Martin Schwemmle, Torsten Seuberlich, Stephen R. Sharpe, Mang Shi, Manuela Sironi, Sophie Smither, Jin-Won Song, Kirsten M. Spann, Jessica R. Spengler, Mark D. Stenglein, Ayato Takada, Robert B. Tesh, Jana Tesikova, Natalie J. Thornburg, Nicole D. Tischler, Yasuhiro Tomitaka, Keizo Tomonaga, Noel Tordo, Kenta Tsunekawa, Massimo Turina, Ioannis E. Tzanetakis, Anna Maria Vaira, Bernadette van den Hoogen, Bert Vanmechelen, Nikos Vasilakis, Martin Verbeek, Susanne von Bargen, Jiro Wada, Victoria Wahl, Peter J. Walker, Anna E. Whitfeld, John Williams, Yuri Wolf, Junki Yamasaki, Hironobu Yanagisawa, Gongyin Ye, Yong-Zhen Zhang, Arnfnn Lodden Okland
Summary: This article presents the updated taxonomy of Negarnaviricota, including the addition of new families, genera, and species, renaming and moving of species, and correction of misspelled names as accepted by the International Committee on Taxonomy of Viruses (ICTV).
ARCHIVES OF VIROLOGY
(2022)
Editorial Material
Virology
Jens H. Kuhn, Steven B. Bradfute, Charles H. Calisher, Boris Klempa, Jonas Klingstrom, Lies Laenen, Gustavo Palacios, Connie S. Schmaljohn, Nicole D. Tischler, Piet Maes
Summary: The official classification of viruses by the ICTV requires complete or nearly complete genome sequences to be deposited in GenBank. This requirement is fairly new, resulting in fragmented or absent genomic sequence information for many classified viruses. This poses challenges for taxon-wide phylogenetic analyses, especially for viruses with segmented genomes. To address this issue for Hantaviridae, the community is urged to provide additional sequence information for incompletely sequenced classified viruses by mid-June 2023 to prevent possible declassification.
Article
Immunology
Luz H. Patino, Susana Guerra, Marina Munoz, Nicolas Luna, Keith Farrugia, Adriana van de Guchte, Zain Khalil, Ana Silvia Gonzalez-Reiche, Matthew M. Hernandez, Radhika Banu, Paras Shrestha, Bernadette Liggayu, Adolfo Firpo Betancourt, David Reich, Carlos Cordon-Cardo, Randy Albrecht, Rebecca Pearl, Viviana Simon, Aria Rooker, Emilia Mia Sordillo, Harm van Bakel, Adolfo Garcia-Sastre, Dusan Bogunovic, Gustavo Palacios, Alberto Paniz Mondolfi, Juan David Ramirez
Summary: Monkeypox (MPOX) is an animal-borne infectious disease endemic to Central/Western Africa. A large multi-country outbreak of MPV, originating in Europe with no links to endemic countries, has rapidly spread worldwide, prompting genomic surveillance efforts. Genomic analysis of MPV-infected patients from New York City revealed that the circulating strains belong to the B.1 lineage, with further differentiation into five sub-lineages. Mutational analysis identified 55 non-synonymous polymorphisms, including those in critical regions for viral function and antiviral treatment target. Comparison between clinical isolates and culture-passaged samples showed no difference.
EMERGING MICROBES & INFECTIONS
(2023)
Article
Microbiology
Carla M. Bellomo, Daniel O. Alonso, Unai Perez-Sautu, Karla Prieto, Sebastian Kehl, Rocio M. Coelho, Natalia Periolo, Nicholas Di Paola, Natalia Ferressini-Gerpe, Jens H. Kuhn, Mariano Sanchez-Lockhart, Gustavo Palacios, Valeria P. Martinez
Summary: This study analyzed the Andes virus (ANDV) using whole-genome sequencing and identified four amino acid substitutions related to cell culture adaptation that attenuated the virus in an animal model. Additionally, three amino acid substitutions associated with efficient person-to-person transmission were identified. These findings suggest that single-nucleotide polymorphisms can be used to predict ANDV virulence and transmissibility.
Article
Virology
Nadine Biedenkopf, Alexander Bukreyev, Kartik Chandran, Nicholas Di Paola, Pierre B. H. Formenty, Anthony Griffiths, Adam J. Hume, Elke Muehlberger, Sergey V. Netesov, Gustavo Palacios, Janusz T. Paweska, Sophie Smither, Ayato Takada, Victoria Wahl, Jens H. Kuhn
Summary: The International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group continues to refine the taxonomy and nomenclature of family Filoviridae in order to reduce confusion and adhere to ICVCN stipulations. Recent changes include the renaming of the genera Ebolavirus and Marburgvirus to Orthoebolavirus and Orthomarburgvirus, respectively. All established species names now follow the ICTV-mandated binomial format. Virus names remain unchanged. Here, we present the revised taxonomy of family Filoviridae approved by the ICTV in April 2023.
ARCHIVES OF VIROLOGY
(2023)
Letter
Immunology
Adrian Lewis, Alejandro Josiowicz, Stella Maris Hirmas Riade, Monica Tous, Gustavo Palacios, Daniel M. Cisterna
Summary: This article reports the detection of cases of monkeypox virus infection in Argentina, alongside a rise in atypical hand-foot-and-mouth syndrome cases caused by enterovirus coxsackie A6. The recommendation is to perform accurate differential virological diagnosis for suspected monkeypox cases.
EMERGING INFECTIOUS DISEASES
(2022)