期刊
CLINICAL INFECTIOUS DISEASES
卷 73, 期 7, 页码 E1754-E1757出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa1847
关键词
cefiderocol; cystic fibrosis; Achromobacter xylosoxidans; pneumonia; lung transplantation
Treatment options for Achromobacter xylosoxidans are limited, but clinical response was observed after cefiderocol treatment. However, microbiologic relapse was common after treatment, notably without emergence of resistance.
Treatment options for Achromobacter xylosoxidans are limited. Eight cystic fibrosis patients with A. xylosoxidans were treated with 12 cefiderocol courses. Pretreatment in vitro resistance was seen in 3 of 8 cases. Clinical response occurred after 11 of 12 treatment courses. However, microbiologic relapse was observed after 11 of 12 treatment courses, notably without emergence of resistance.
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