Article
Mathematics
Derek Ka-Hei Lai, Ethan Shiu-Wang Cheng, Bryan Pak-Hei So, Ye-Jiao Mao, Sophia Ming-Yan Cheung, Daphne Sze Ki Cheung, Duo Wai-Chi Wong, James Chung-Wai Cheung
Summary: This study aimed to evaluate the classification performance of Transformer models and convolutional networks in identifying swallowing and non-swallowing tasks through depth video data. The results showed that convolutional neural networks outperformed the Transformer models, and X3D was the best model with good-to-excellent performance in classifying swallowing and non-swallowing conditions. Future studies should consider collecting more data for pretraining and developing a hyperparameter tuning strategy for Transformer models.
Article
Geriatrics & Gerontology
Annie Brooks
Summary: People with Parkinson's disease are more prone to aspiration pneumonia compared to others. Aspiration pneumonia, caused by swallowing issues, is a major cause of death among Parkinson's patients, accounting for 25% of Parkinson's deaths. Limited evidence exists regarding the most effective strategies to balance the competing needs of each Parkinson's patient.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Veterinary Sciences
Megan Grobman, Enrico Carluen, Carol R. Reinero
Summary: The study utilized VFSS to identify the incidence of penetration-aspiration (P-A) in dogs, finding a 39% incidence rate, with some dogs presenting with P-A without respiratory clinical signs. Pharyngeal and esophageal dysphagia were more common in dogs with P-A, and pharyngeal weakness and esophago-oropharyngeal reflux were identified as independent predictors of P-A.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Seoyon Yang, Yoo Jin Choo, Min Cheol Chang
Summary: Early screening for dysphagia in acute stroke patients can prevent the development of pneumonia.
Article
Audiology & Speech-Language Pathology
Atsuko Kurosu, Sheila R. Pratt, Catherine Palmer, Susan Shaiman
Summary: The study aimed to examine the linguistic influences of the verbal command on swallowing, showing that language facilitation was observed in swallowing. This could be a useful compensatory technique for patients with difficulty initiating oropharyngeal swallows.
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH
(2021)
Article
Critical Care Medicine
Takashi Hongo, Ryohei Yamamoto, Keibun Liu, Takahiko Yaguchi, Hisashi Dote, Ryusuke Saito, Tomoyuki Masuyama, Kosuke Nakatsuka, Shinichi Watanabe, Takahiro Kanaya, Tomoya Yamaguchi, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao
Summary: Delayed initiation of speech and language therapy post-extubation in patients with post-extubation dysphagia was associated with persistent dysphagia or death. Early initiation of speech and language therapy may prevent this complication post-extubation.
Article
Otorhinolaryngology
Linda M. Rowe, Nadine P. Connor, John A. Russell
Summary: This study assessed the effect of CRT on respiratory-swallow coordination using a rat model and found that CRT rats had significantly increased postswallow inhale events. The findings suggest that the rat CRT model is valid for studying respiratory-swallow coordination in HNC patients undergoing CRT.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Review
Respiratory System
Rumi Ueha, Redentor B. Magdayao, Misaki Koyama, Taku Sato, Takao Goto, Tatsuya Yamasoba
Summary: Severe dysphagia can lead to life-threatening conditions such as intractable pneumonia. Surgical intervention is necessary to prevent intractable aspiration and its complications. This review aims to increase awareness among medical professionals about aspiration prevention surgeries and guide the selection of appropriate surgical options.
RESPIRATORY RESEARCH
(2023)
Review
Physiology
Teresa Pitts, Kimberly E. Iceman
Summary: Despite centuries of investigation, there are still questions and controversies regarding the origin and motor pattern of swallow. Two significant topics include inspiratory muscle activity during swallow and anatomical boundaries of the swallow pattern generator. This article discusses the history and current theories surrounding these topics, as well as potential advantages and neural basis for such activities.
Article
Public, Environmental & Occupational Health
Rakesh Kumar, Lalit Dar, Ritvik Amarchand, Siddhartha Saha, Kathryn E. Lafond, Debjani R. Purakayastha, Ramesh Kumar, Avinash Choudekar, Giridara Gopal, Shivram Dhakad, Venkatesh Vinayak Narayan, Abhishek Wahi, Reshmi Chhokar, Stephen Lindstrom, Brett Whitaker, Aashish Choudhary, A. B. Dey, Anand Krishnan
Summary: Limited data on acute lower respiratory tract infection (LRTI) among older adults in low- and middle-income countries were investigated over a two-year period. Chronic bronchitis was identified as an important risk factor, with influenza virus and RSV being major viral pathogens in this population. The incidence of LRTI was found to be substantial in older adults, with influenza and RSV being commonly detected.
JOURNAL OF GLOBAL HEALTH
(2021)
Article
Otorhinolaryngology
Apoorva T. Ramaswamy, Daniel Cates, Lisa Evangelista, Mayuri Srikanth, Peter Belafsky
Summary: This study aimed to evaluate the feasibility of using Calcium Hydroxylapatite (CaHA) for tongue base augmentation in patients with swallowing impairment due to tongue base atrophy. The results showed that the procedure was easily performed and the CaHA flowed easily into the tongue base without any complications. Further investigation is needed to evaluate the clinical safety and efficacy of this method.
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY
(2023)
Article
Multidisciplinary Sciences
Dougho Park, Seok Il Son, Min Sol Kim, Tae Yeon Kim, Jun Hwa Choi, Sang-Eok Lee, Daeyoung Hong, Mun-Chul Kim
Summary: Machine learning models were established to screen aspiration in patients with acute stroke. The Gugging Swallowing Screen (GUSS) was evaluated and compared with machine learning models. Among the models, the ridge regression model performed the best, with a higher sensitivity than the GUSS. The modified Rankin scale was identified as the most important feature for machine learning performance. The proposed machine learning prediction models are valid and practical for screening aspiration in patients with acute stroke.
SCIENTIFIC REPORTS
(2023)
Article
Public, Environmental & Occupational Health
Nieves Sopena, Valentina Isernia, Irma Casas, Beatriz Diez, Ignasi Guasch, Miquel Sabria, Maria Luisa Pedro-Botet
Summary: The intervention successfully reduced the incidence of non-ventilator-associated hospital-acquired pneumonia (NV-HAP) and improved compliance with preventive measures.
AMERICAN JOURNAL OF INFECTION CONTROL
(2023)
Article
Medicine, General & Internal
Poyin Huang, Yi-Chiung Hsu, Chien-Hsun Li, Sun-Wung Hsieh, Kuo-Wei Lee, Kun-Han Wu, Wen-Ching Chen, Chung-Wei Lin, Chun-Hung Chen
Summary: In this study, 100 dysphagia patients were evaluated using various methods and followed up to assess the association between dysphagia severity and subsequent pneumonia. Only VF-DSS was significantly associated with pneumonia, while other evaluations showed no correlation. Therefore, VF-DSS can be used to predict the occurrence of pneumonia in dysphagia patients.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
(2023)
Article
Neurosciences
Mei-Ru Wu, Yi-Tong Chen, Zi-Xiao Li, Hong-Qiu Gu, Kai-Xuan Yang, Yun-Yun Xiong, Yong-Jun Wang, Chun-Juan Wang
Summary: This study analyzed the rates of dysphagia screening (DS) and pneumonia among subarachnoid hemorrhage (SAH) patients in China, and found that DS was associated with a lower risk of pneumonia.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Article
Psychology, Clinical
Adrianna M. Ratajska, Francesca Lopez, Lauren Kenney, Charles Jacobson, Kelly D. Foote, Michael S. Okun, Dawn Bowers
Summary: The study identified three cognitive subtypes of ET patients undergoing DBS, with 27.4% meeting criteria for MCI. The majority of MCI cases were in the Low Executive or Low Memory Multi-Domain groups, with the latter having a higher percentage of members classified as MCI. Future work should focus on examining these subgroups for progression to dementia.
CLINICAL NEUROPSYCHOLOGIST
(2022)
Article
Psychology, Multidisciplinary
Adrianna M. Ratajska, Anne N. Nisenzon, Francesca Lopez, Alexandra L. Clark, Didem Gokcay, Michael S. Okun, Dawn Bowers
Summary: The study found that patients with left-sided symptom onset in Parkinson's disease were slower to initiate anger and happiness facial expressions compared to patients with right-sided symptom onset and healthy controls.
Article
Neurosciences
Takashi Tsuboi, Yuki Satake, Keita Hiraga, Katsunori Yokoi, Makoto Hattori, Masashi Suzuki, Kazuhiro Hara, Adolfo Ramirez-Zamora, Michael S. Okun, Masahisa Katsuno
Summary: Selegiline, rasagiline, and safinamide, three MAO-BIs drugs, have different effects on the quality of life and non-motor symptoms of patients with Parkinson's disease. However, the understanding of these effects is still unclear and further high-quality studies are needed to verify them.
NPJ PARKINSONS DISEASE
(2022)
Article
Psychology, Clinical
Adrianna M. Ratajska, Bonnie M. Scott, Francesca V. Lopez, Lauren E. Kenney, Kelly D. Foote, Michael S. Okun, Catherine Price, Dawn Bowers
Summary: This study compared the severity of mood symptoms in PD, ET, and HC groups and examined the relationship between mood and cognition. The results showed that both PD and ET groups reported more mood symptoms and lower cognitive scores compared to the HC group. The relationship between mood and cognition differed between PD and ET groups.
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
(2022)
Article
Clinical Neurology
Celia Painous, Maria J. Marti, Holm Graessner, Andrea Paola Camargo, Shaimaa Ibrahim El-Jaafary, Daniel Martinez-Ramirez, Oluwadamilola O. Ojo, Funmilola T. Taiwo, Roopa Rajan, Mario Cornejo-Olivas, Biniyam A. Ayele, Houyam Tibar, Mary Kearney, Emilia Gatto, Marina AJ. Tijssen
Summary: An exploratory survey conducted by the Rare Movement Disorders Study Group of the International Parkinson and Movement Disorders Society aimed to evaluate the management of rare movement disorders at the international level and address care needs. The survey results revealed variation in the availability of movement disorders experts and difficulties in accessing care, diagnostic tests, and therapeutic options across different regions.
PARKINSONISM & RELATED DISORDERS
(2023)
Article
Clinical Neurology
Bonnie M. Scott, Robert S. Eisinger, Amtul-noor Rana, Jared F. Benge, Robin C. Hilsabeck, Michael S. Okun, Aysegul Gunduz, Dawn Bowers
Summary: Patients with both apathy and ICD exhibit significantly greater symptoms of positive and negative urgency, consummatory anhedonia, lack of premeditation and perseverance. Patients with apathy only showed significantly greater anticipatory anhedonia than those with ICD only or neither.
APPLIED NEUROPSYCHOLOGY-ADULT
(2022)
Article
Clinical Neurology
Aparna Wagle Shukla, Caroline Lunny, Ibrahim Hisham, Jackson Cagle, Joyce Malea, Alfonso Santos, Ashutosh M. Shukla
Summary: This study describes four patients who developed tremors after kidney transplant surgery and receiving treatment with tacrolimus immunosuppressant. The tremors mainly affected the hands, and limb cooling was found to temporarily reduce the tremor severity. Limb cooling may be considered as a therapeutic option for tacrolimus-induced tremor.
TREMOR AND OTHER HYPERKINETIC MOVEMENTS
(2023)
Review
Psychology, Multidisciplinary
Seyed-Mohammad Fereshtehnejad, Mayela Rodriguez-Violante, Monica S. Ponce-Rivera, Daniel Martinez-Ramirez, Adolfo Ramirez-Zamora
Summary: The diverse clinical manifestations of Parkinson's disease require the involvement of multiple healthcare professionals. The COVID-19 pandemic has posed challenges to implementing multidisciplinary care models, but innovative virtual platforms are being developed to address this issue.
BEHAVIORAL SCIENCES
(2022)
Article
Neurosciences
Bradley J. Wilkes, Emily R. Tobin, David J. Arpin, Wei-en Wang, Michael S. Okun, Michael S. Jaffee, Nikolaus R. McFarland, Daniel M. Corcos, David E. Vaillancourt
Summary: Objective measures of disease progression using the Purdue Pegboard Test (PPT) were conducted in patients with Parkinson's disease (PD), atypical Parkinsonism, and healthy controls. The decline in PPT performance in PD patients correlated with motor symptom progression, while no such decline was seen in controls. Neuroimaging measures from the basal ganglia were significant predictors of PPT performance in PD, and cortical, basal ganglia, and cerebellar regions were predictors for atypical Parkinsonism. Accelerometry in PD patients showed diminished acceleration range and irregular patterns, which correlated with PPT scores.
NPJ PARKINSONS DISEASE
(2023)
Article
Clinical Neurology
Robert S. Eisinger, Michael S. Okun, Stephanie Cernera, Jackson Cagle, Matthew Beke, Adolfo Ramirez-Zamora, B. Hope Kim, Daniel A. N. Barbosa, Liming Qiu, Pavan Vaswani, Whitley W. Aamodt, Casey H. Halpern, Kelly D. Foote, Aysegul Gunduz, Leonardo Almeida
Summary: Weight loss in Parkinson's disease patients accelerates before death. Patients who underwent deep brain stimulation surgery gained weight, and higher post-operative weight correlates with longer survival.
PARKINSONISM & RELATED DISORDERS
(2023)
Review
Pharmacology & Pharmacy
Aparna Wagle Shukla, Caroline Lunny, Omar Mahboob, Uzair Khalid, Malea Joyce, Nivedita Jha, Nandakumar Nagaraja, Ashutosh M. Shukla
Summary: This study reviewed 81 studies and found that calcineurin inhibitors, such as cyclosporine and tacrolimus, can induce tremors, while non-calcineurin inhibitors, such as sirolimus and everolimus, may also cause tremors. Tremors were more common in kidney transplant and bone marrow transplant patients, and there is limited research on risk factors, treatment strategies, and outcomes for tremors.
Article
Clinical Neurology
Daniel Martinez-Ramirez, Alejandro Almaraz-Espinoza, Alejandro Banegas-Lagos, Paola Bazan-Rodriguez, Edna S. Velazquez-Avila, Arnulfo Gonzalez-Cantu, Amin Cervantes-Arriaga, Mayela Rodriguez-Violante
Summary: This study aimed to investigate the relationship between dopaminergic-induced complications and satisfaction with life in patients with Parkinson's disease. The results showed that motor fluctuations had a detrimental effect on patients' life satisfaction, while dyskinesias were not significantly correlated. The study suggests that strategies to reduce motor fluctuations and improve understanding of their impact on patients' lives may help minimize the negative effects of these complications on Parkinson's disease patients.
REVISTA MEXICANA DE NEUROCIENCIA
(2022)
Article
Clinical Neurology
Yoon Jin Choi, Basma Yacoubi, Agostina Casamento-Moran, Stefan Delmas, Bradley J. Wilkes, Christopher W. Hess, Aparna Wagle Shukla, Kelly D. Foote, David E. Vaillancourt, Michael S. Okun, Evangelos A. Christou
Summary: The study found that VIM DBS was effective in improving gait and balance in ET DBS patients. The improvements in gait and postural balance were associated with a reduction in axial tremor during the tasks.
TREMOR AND OTHER HYPERKINETIC MOVEMENTS
(2022)
Review
Clinical Neurology
Aparna Wagle Shukla
Summary: Peripheral stimulation techniques, such as the Cala system, show promise in treating symptoms of essential tremor. However, the current clinical evidence on efficacy is inconsistent and more data is needed to establish peripheral nerve stimulation as a standard of care.
TREMOR AND OTHER HYPERKINETIC MOVEMENTS
(2022)