MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice

The integrative biology of type 2 diabetes

(2019) Michael Roden et al.   NATURE

An Integrated View of Immunometabolism

(2018) Yun Sok Lee et al.   CELL

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure

(2018) Prashant Rajbhandari et al.   CELL

Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise

(2018) Martin Whitham et al.   Cell Metabolism

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

(2018) Jun Yoshino et al.   Cell Metabolism

An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

(2018) Clair Crewe et al.   CELL

Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

(2018) Claudiane Guay et al.   Cell Metabolism

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Inflammatory mechanisms linking obesity and metabolic disease

(2017) Alan R. Saltiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

A bead-assisted flow cytometry method for the semi-quantitative analysis of Extracellular Vesicles

(2017) Henar Suárez et al.   Scientific Reports

Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance

(2016) Pingping Li et al.   CELL

Trends in Obesity Prevalence Among Children and Adolescents in the United States, 1988-1994 Through 2013-2014

(2016) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAMPT-Mediated NAD + Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice

(2016) Kelly L. Stromsdorfer et al.   Cell Reports

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes

(2015) Pingping Li et al.   NATURE MEDICINE

Regulation of metabolism by the innate immune system

(2015) Denise E. Lackey et al.   Nature Reviews Endocrinology

Inflamed macrophage microvesicles induce insulin resistance in human adipocytes

(2015) Yaqin Zhang et al.   Nutrition & Metabolism

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

(2015) Donald G. Phinney et al.   Nature Communications

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Mesenchymal stem cells as cellular vectors for pediatric neurological disorders

(2014) Donald G. Phinney et al.   BRAIN RESEARCH

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Characterization of Distinct Subpopulations of Hepatic Macrophages in HFD/Obese Mice

(2014) Hidetaka Morinaga et al.   DIABETES

Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease

(2013) Steven J. Van Dyken et al.   Annual Review of Immunology

The Origins and Drivers of Insulin Resistance

(2013) Andrew M.F. Johnson et al.   CELL

Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

(2013) Xiaoyuan Xu et al.   Cell Metabolism

Pro-Inflammatory macrophages increase in skeletal muscle of high fat-Fed mice and correlate with metabolic risk markers in humans

(2013) Lisbeth N. Fink et al.   Obesity

Metabolic Syndrome, Insulin Resistance, and Roles of Inflammation – Mechanisms and Therapeutic Targets

(2012) Giulio R. Romeo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

(2011) Jun Yoshino et al.   Cell Metabolism

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity

(2008) Kihwa Kang et al.   Cell Metabolism