Building inner ears: recent advances and future challenges for in vitro organoid systems
出版年份 2020 全文链接
标题
Building inner ears: recent advances and future challenges for in vitro organoid systems
作者
关键词
-
出版物
CELL DEATH AND DIFFERENTIATION
Volume 28, Issue 1, Pages 24-34
出版商
Springer Science and Business Media LLC
发表日期
2020-12-14
DOI
10.1038/s41418-020-00678-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The emergence of transcriptional identity in somatosensory neurons
- (2020) Nikhil Sharma et al. NATURE
- Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea
- (2020) Michael Hoa et al. Frontiers in Molecular Neuroscience
- Genetic Hearing Loss Associated With Autoinflammation
- (2020) Hiroshi Nakanishi et al. Frontiers in Neurology
- Hear, Hear for Notch: Control of Cell Fates in the Inner Ear by Notch Signaling
- (2020) Rogers Brown et al. Biomolecules
- Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery
- (2020) Arun Sharma et al. Cell Stem Cell
- Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal
- (2020) Ksenia Gnedeva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of the development of the mouse cochlear epithelium at the single cell level
- (2020) Likhitha Kolla et al. Nature Communications
- Production and Characterization of Human Macrophages from Pluripotent Stem Cells
- (2020) Martha Lopez-Yrigoyen et al. Jove-Journal of Visualized Experiments
- Progress in Modeling and Targeting Inner Ear Disorders with Pluripotent Stem Cells
- (2020) Pei-Ciao Tang et al. Stem Cell Reports
- Retinoic acid synthesis and autoregulation mediate zonal patterning of vestibular organs and inner ear morphogenesis
- (2020) Kazuya Ono et al. DEVELOPMENT
- Hair-bearing human skin generated entirely from pluripotent stem cells
- (2020) Jiyoon Lee et al. NATURE
- Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction
- (2020) Goodwell Nzou et al. Scientific Reports
- Inner Ear Gene Therapies Take Off: Current Promises and Future Challenges
- (2020) Sedigheh Delmaghani et al. Journal of Clinical Medicine
- Stem cell-based approaches: Possible route to hearing restoration?
- (2020) María Beatriz Durán-Alonso World Journal of Stem Cells
- High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays
- (2020) Nathalie Brandenberg et al. Nature Biomedical Engineering
- Migration and fate of vestibular melanocytes during development of the human inner ear
- (2020) Edward S.A. van Beelen et al. Developmental Neurobiology
- Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis
- (2020) Brisa Palikuqi et al. NATURE
- Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis
- (2020) Lu Han et al. Nature Communications
- Human blood vessel organoids as a model of diabetic vasculopathy
- (2019) Reiner A. Wimmer et al. NATURE
- Delivery of therapeutics to the inner ear: The challenge of the blood-labyrinth barrier
- (2019) Sophie Nyberg et al. Science Translational Medicine
- Flow-enhanced vascularization and maturation of kidney organoids in vitro
- (2019) Kimberly A. Homan et al. NATURE METHODS
- Tubuloids derived from human adult kidney and urine for personalized disease modeling
- (2019) Frans Schutgens et al. NATURE BIOTECHNOLOGY
- Human neural crest induction by temporal modulation of WNT activation
- (2019) Gustavo A. Gomez et al. DEVELOPMENTAL BIOLOGY
- An Atlas of Vagal Sensory Neurons and Their Molecular Specialization
- (2019) Jussi Kupari et al. Cell Reports
- Neuronal diversity in the somatosensory system: bridging the gap between cell type and function
- (2019) Graziana Gatto et al. CURRENT OPINION IN NEUROBIOLOGY
- Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells
- (2019) Andrea Manfrin et al. NATURE METHODS
- Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids
- (2019) Pei-Ciao Tang et al. Stem Cell Reports
- Progenitor Cells from the Adult Human Inner Ear
- (2019) Pascal Senn et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Inner ear organoids: new tools to understand neurosensory cell development, degeneration and regeneration
- (2019) Marta Roccio et al. DEVELOPMENT
- TBX1 is required for normal stria vascularis and semicircular canal development
- (2019) Cong Tian et al. DEVELOPMENTAL BIOLOGY
- Controlled modelling of human epiblast and amnion development using stem cells
- (2019) Yi Zheng et al. NATURE
- Novel insights into inner ear development and regeneration for targeted hearing loss therapies
- (2019) Marta Roccio et al. HEARING RESEARCH
- Decoding human fetal liver haematopoiesis
- (2019) Dorin-Mirel Popescu et al. NATURE
- Engineering of human brain organoids with a functional vascular-like system
- (2019) Bilal Cakir et al. NATURE METHODS
- Forgotten Fibrocytes: A Neglected, Supporting Cell Type of the Cochlea With the Potential to be an Alternative Therapeutic Target in Hearing Loss
- (2019) David N. Furness Frontiers in Cellular Neuroscience
- Single Cell and Single Nucleus RNA-Seq Reveal Cellular Heterogeneity and Homeostatic Regulatory Networks in Adult Mouse Stria Vascularis
- (2019) Soumya Korrapati et al. Frontiers in Molecular Neuroscience
- Barhl 1 is required for the differentiation of inner ear hair cell-like cells from mouse embryonic stem cells
- (2018) Chao Zhong et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling
- (2018) Goodwell Nzou et al. Scientific Reports
- Transcriptional Dynamics of Hair-Bundle Morphogenesis Revealed with CellTrails
- (2018) Daniel C. Ellwanger et al. Cell Reports
- Regenerating hair cells in human vestibular sensory epithelia
- (2018) Ruth Rebecca Taylor et al. eLife
- Hair Cell Mechanotransduction Regulates Spontaneous Activity and Spiral Ganglion Subtype Specification in the Auditory System
- (2018) Shuohao Sun et al. CELL
- Sensory Neuron Diversity in the Inner Ear Is Shaped by Activity
- (2018) Brikha R. Shrestha et al. CELL
- Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
- (2018) Minjin Jeong et al. Cell Death & Disease
- Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors
- (2018) Marta Roccio et al. Nature Communications
- Pluripotent stem cell-derived cochlear cells: a challenge in constant progress
- (2018) Amandine Czajkowski et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Neural crest contributions to the ear: Implications for congenital hearing disorders
- (2018) K. Elaine Ritter et al. HEARING RESEARCH
- Peripheral Vestibular Disorders
- (2018) Roland Hülse et al. OTOLOGY & NEUROTOLOGY
- Microglia innately develop within cerebral organoids
- (2018) Paul R. Ormel et al. Nature Communications
- Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers
- (2018) Stephen McInturff et al. Biology Open
- Enriched Differentiation of Human Otic Sensory Progenitor Cells Derived From Induced Pluripotent Stem Cells
- (2018) Hanae Lahlou et al. Frontiers in Molecular Neuroscience
- Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome
- (2018) Makoto Hosoya et al. Regenerative Therapy
- Noise-induced cochlear synaptopathy in rhesus monkeys ( Macaca mulatta )
- (2017) M.D. Valero et al. HEARING RESEARCH
- Assembly of functionally integrated human forebrain spheroids
- (2017) Fikri Birey et al. NATURE
- Generation of inner ear organoids containing functional hair cells from human pluripotent stem cells
- (2017) Karl R Koehler et al. NATURE BIOTECHNOLOGY
- Differentiation of V2a interneurons from human pluripotent stem cells
- (2017) Jessica C. Butts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emergent cellular self-organization and mechanosensation initiate follicle pattern in the avian skin
- (2017) Amy E. Shyer et al. SCIENCE
- Generation of Otic Sensory Neurons from Mouse Embryonic Stem Cells in 3D Culture
- (2017) Michael Perny et al. Frontiers in Cellular Neuroscience
- Cisplatin is retained in the cochlea indefinitely following chemotherapy
- (2017) Andrew M. Breglio et al. Nature Communications
- Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss
- (2017) Makoto Hosoya et al. Cell Reports
- Hearing crosstalk: the molecular conversation orchestrating inner ear dorsoventral patterning
- (2017) Sho Ohta et al. Wiley Interdisciplinary Reviews-Developmental Biology
- Effects of genetic correction on the differentiation of hair cell-like cells from iPSCs with MYO15A mutation
- (2016) J-R Chen et al. CELL DEATH AND DIFFERENTIATION
- WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate
- (2016) Alan W. Leung et al. DEVELOPMENT
- Induction of differentiation of human embryonic stem cells into functional hair-cell-like cells in the absence of stromal cells
- (2016) Jie Ding et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Single-cell analysis delineates a trajectory toward the human early otic lineage
- (2016) Megan Ealy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Directed Differentiation of Human Embryonic Stem Cells Toward Placode-Derived Spiral Ganglion-Like Sensory Neurons
- (2016) Akihiro J. Matsuoka et al. Stem Cells Translational Medicine
- Genetic Correction of Induced Pluripotent Stem Cells From a Deaf Patient With MYO7A Mutation Results in Morphologic and Functional Recovery of the Derived Hair Cell-Like Cells
- (2016) Zi-Hua Tang et al. Stem Cells Translational Medicine
- In Vitro Models of GJB2-Related Hearing Loss Recapitulate Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea
- (2016) Ichiro Fukunaga et al. Stem Cell Reports
- Gene Expression Profiles of the Cochlea and Vestibular Endorgans
- (2015) Shin-ya Nishio et al. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
- Development of the stria vascularis and potassium regulation in the human fetal cochlea: Insights into hereditary sensorineural hearing loss
- (2015) Heiko Locher et al. Developmental Neurobiology
- Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing
- (2015) Ruth R. Taylor et al. NEUROBIOLOGY OF AGING
- Limited hair cell induction from human induced pluripotent stem cells using a simple stepwise method
- (2015) Hiroe Ohnishi et al. NEUROSCIENCE LETTERS
- Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear
- (2015) Joseph C. Burns et al. Nature Communications
- Early steps in inner ear development: induction and morphogenesis of the otic placode
- (2015) Xiaorei Sai et al. Frontiers in Pharmacology
- Segregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control
- (2014) Steven Raft et al. CELL AND TISSUE RESEARCH
- The evolutionary history of vertebrate cranial placodes II. Evolution of ectodermal patterning
- (2014) Gerhard Schlosser et al. DEVELOPMENTAL BIOLOGY
- Sound Strategies for Hearing Restoration
- (2014) G. S. G. Geleoc et al. SCIENCE
- Inner Ear Hair Cell-Like Cells from Human Embryonic Stem Cells
- (2014) Mohammad Ronaghi et al. STEM CELLS AND DEVELOPMENT
- Signaling pathways regulating ectodermal cell fate choices
- (2013) Cédric Patthey et al. EXPERIMENTAL CELL RESEARCH
- Cytoplasmic Mislocalization of POU3F4 Due to Novel Mutations Leads to Deafness in Humans and Mice
- (2013) Thomas Parzefall et al. HUMAN MUTATION
- Ectopic Expression of Activated Notch or SOX2 Reveals Similar and Unique Roles in the Development of the Sensory Cell Progenitors in the Mammalian Inner Ear
- (2013) W. Pan et al. JOURNAL OF NEUROSCIENCE
- Neurosensory development and cell fate determination in the human cochlea
- (2013) Heiko Locher et al. Neural Development
- Lineage Analysis of the Late Otocyst Stage Mouse Inner Ear by Transuterine Microinjection of A Retroviral Vector Encoding Alkaline Phosphatase and an Oligonucleotide Library
- (2013) Han Jiang et al. PLoS One
- Restoration of auditory evoked responses by human ES-cell-derived otic progenitors
- (2012) Wei Chen et al. NATURE
- Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway
- (2012) Thomas M. Coate et al. NEURON
- Dual embryonic origin of the mammalian otic vesicle forming the inner ear
- (2011) L. Freyer et al. DEVELOPMENT
- Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development
- (2011) A. S. Brown et al. DEVELOPMENT
- Impaired stria vascularis integrity upon loss of E-cadherin in basal cells
- (2011) Mark-Oliver Trowe et al. DEVELOPMENTAL BIOLOGY
- Physiopathology of the cochlear microcirculation
- (2011) Xiaorui Shi HEARING RESEARCH
- Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia
- (2011) B. K. Chauhan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pou3f4 deficiency causes defects in otic fibrocytes and stria vascularis by different mechanisms
- (2010) Mee Hyun Song et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- BMP Signaling Is Necessary for Patterning the Sensory and Nonsensory Regions of the Developing Mammalian Cochlea
- (2010) T. Ohyama et al. JOURNAL OF NEUROSCIENCE
- Distinct contributions from the hindbrain and mesenchyme to inner ear morphogenesis
- (2009) Jennifer K. Liang et al. DEVELOPMENTAL BIOLOGY
- Human Fetal Auditory Stem Cells Can Be Expanded In Vitro and Differentiate Into Functional Auditory Neurons and Hair Cell-Like Cells
- (2009) Wei Chen et al. STEM CELLS
- Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes
- (2008) M.-O. Trowe et al. DEVELOPMENT
- Progressive restriction of otic fate: the role of FGF and Wnt in resolving inner ear potential
- (2008) S. Freter et al. DEVELOPMENT
- Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode
- (2008) C. S. Jayasena et al. DEVELOPMENT
- Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network
- (2008) E. Dessaud et al. DEVELOPMENT
- Cooperative Function of Tbx1 and Brn4 in the Periotic Mesenchyme is Necessary for Cochlea Formation
- (2008) Evan M. Braunstein et al. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
- Stria vascularis and vestibular dark cells: characterisation of main structures responsible for inner-ear homeostasis, and their pathophysiological relations
- (2008) R R Ciuman JOURNAL OF LARYNGOLOGY AND OTOLOGY
- Hedgehog Signaling Regulates Sensory Cell Formation and Auditory Function in Mice and Humans
- (2008) E. C. Driver et al. JOURNAL OF NEUROSCIENCE
- Fgf20 Is Required for Sensory Epithelial Specification in the Developing Cochlea
- (2008) T. Hayashi et al. JOURNAL OF NEUROSCIENCE
- Bmp4 Is Essential for the Formation of the Vestibular Apparatus that Detects Angular Head Movements
- (2008) Weise Chang et al. PLoS Genetics
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started