Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos

Validation of concurrent preimplantation genetic testing for polygenic and monogenic disorders, structural rearrangements, and whole and segmental chromosome aneuploidy with a single universal platform

(2019) Nathan R. Treff et al.   European Journal of Medical Genetics

Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells

(2019) Ido Sagi et al.   Cell Stem Cell

Search-and-replace genome editing without double-strand breaks or donor DNA

(2019) Andrew V. Anzalone et al.   NATURE

Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes

(2018) L. Zakarin Safier et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements

(2018) Michael Kosicki et al.   NATURE BIOTECHNOLOGY

CRISPR/Cas9 cleavages in budding yeast reveal templated insertions and strand-specific insertion/deletion profiles

(2018) Brenda R. Lemos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ma et al. reply

(2018) Hong Ma et al.   NATURE

Inter-homologue repair in fertilized human eggs?

(2018) Dieter Egli et al.   NATURE

Large deletions induced by Cas9 cleavage

(2018) Fatwa Adikusuma et al.   NATURE

Targeted Deletion of an Entire Chromosome Using CRISPR/Cas9

(2017) Fatwa Adikusuma et al.   MOLECULAR THERAPY

Correction of a pathogenic gene mutation in human embryos

(2017) Hong Ma et al.   NATURE

Genome editing reveals a role for OCT4 in human embryogenesis

(2017) Norah M. E. Fogarty et al.   NATURE

Genomic instability during reprogramming by nuclear transfer is DNA replication dependent

(2017) Gloryn Chia et al.   NATURE CELL BIOLOGY

Tripolar mitosis and partitioning of the genome arrests human preimplantation development in vitro

(2017) Christian S. Ottolini et al.   Scientific Reports

Rawcopy: Improved copy number analysis with Affymetrix arrays

(2016) Markus Mayrhofer et al.   Scientific Reports

Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates

(2015) Christian S Ottolini et al.   NATURE GENETICS

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

(2015) Agnel Sfeir et al.   TRENDS IN BIOCHEMICAL SCIENCES

Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development

(2015) Rajiv C. McCoy et al.   PLoS Genetics

CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

(2015) Puping Liang et al.   Protein & Cell

Aneuploidy across individual chromosomes at the embryonic level in trophectoderm biopsies: changes with patient age and chromosome structure

(2014) Jason M. Franasiak et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells

(2014) Mitsutoshi Yamada et al.   NATURE

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

(2014) Y. Lin et al.   NUCLEIC ACIDS RESEARCH

Enhanced Efficiency of Human Pluripotent Stem Cell Genome Editing through Replacing TALENs with CRISPRs

(2013) Qiurong Ding et al.   Cell Stem Cell

Repair of Strand Breaks by Homologous Recombination

(2013) M. Jasin et al.   Cold Spring Harbor Perspectives in Biology

The in vitro survival of human monosomies and trisomies as embryonic stem cells

(2012) Juan Carlos Biancotti et al.   Stem Cell Research

Optimal Timing of Inner Cell Mass Isolation Increases the Efficiency of Human Embryonic Stem Cell Derivation and Allows Generation of Sibling Cell Lines

(2009) Alice E. Chen et al.   Cell Stem Cell

Chromosome instability is common in human cleavage-stage embryos

(2009) Evelyne Vanneste et al.   NATURE MEDICINE

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

(2009) P. J. Hastings et al.   PLoS Genetics

EYS, encoding an ortholog of Drosophila spacemaker, is mutated in autosomal recessive retinitis pigmentosa

(2008) Mai M Abd El-Aziz et al.   NATURE GENETICS