Generation of Functional Human 3D Cortico-Motor Assembloids

Self-Organizing 3D Human Trunk Neuromuscular Organoids

(2020) Jorge-Miguel Faustino Martins et al.   Cell Stem Cell

Brainstem neurons that command mammalian locomotor asymmetries

(2020) Jared M. Cregg et al.   NATURE NEUROSCIENCE

Characterization of Human iPSC-derived Spinal Motor Neurons by Single-cell RNA Sequencing

(2020) Louise Thiry et al.   NEUROSCIENCE

Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates

(2020) Nicola Micali et al.   Cell Reports

Assembling human brain organoids

(2019) Sergiu P. Paşca   SCIENCE

Cerebral organoids at the air–liquid interface generate diverse nerve tracts with functional output

(2019) Stefano L. Giandomenico et al.   NATURE NEUROSCIENCE

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

(2019) Julien Delile et al.   DEVELOPMENT

hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids

(2019) Yangfei Xiang et al.   Cell Stem Cell

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

BMP4 patterns Smad activity and generates stereotyped cell fate organization in spinal organoids

(2019) Nathalie Duval et al.   DEVELOPMENT

Organoid single-cell genomic atlas uncovers human-specific features of brain development

(2019) Sabina Kanton et al.   NATURE

V2a interneuron differentiation from mouse and human pluripotent stem cells

(2019) Jessica C. Butts et al.   Nature Protocols

Spinal Circuits for Touch, Pain, and Itch

(2018) Stephanie C. Koch et al.   Annual Review of Physiology

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Genetic identification of brain cell types underlying schizophrenia

(2018) Nathan G. Skene et al.   NATURE GENETICS

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

(2018) Yingxiao Shi et al.   NATURE MEDICINE

Single-cell profiling of the developing mouse brain and spinal cord with split-pool barcoding

(2018) Alexander B. Rosenberg et al.   SCIENCE

Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior

(2018) Anupama Sathyamurthy et al.   Cell Reports

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

Three-dimensional induction of dorsal, intermediate and ventral spinal cord tissues from human pluripotent stem cells

(2018) Takenori Ogura et al.   DEVELOPMENT

Generation and assembly of human brain region–specific three-dimensional cultures

(2018) Steven A. Sloan et al.   Nature Protocols

Reliability of human cortical organoid generation

(2018) Se-Jin Yoon et al.   NATURE METHODS

Building Models of Brain Disorders with Three-Dimensional Organoids

(2018) Neal D. Amin et al.   NEURON

Assembly of functionally integrated human forebrain spheroids

(2017) Fikri Birey et al.   NATURE

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells

(2017) Steven A. Sloan et al.   NEURON

Control of species-dependent cortico-motoneuronal connections underlying manual dexterity

(2017) Zirong Gu et al.   SCIENCE

MUSCLEMOTION

(2017) Luca Sala et al.   CIRCULATION RESEARCH

Functional Connectivity under Optogenetic Control Allows Modeling of Human Neuromuscular Disease

(2016) Julius A. Steinbeck et al.   Cell Stem Cell

Making sense out of spinal cord somatosensory development

(2016) Helen C. Lai et al.   DEVELOPMENT

Modeling ALS with motor neurons derived from human induced pluripotent stem cells

(2016) Samuel Sances et al.   NATURE NEUROSCIENCE

Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro

(2016) Jérome Chal et al.   Nature Protocols

Decoding the organization of spinal circuits that control locomotion

(2016) Ole Kiehn   NATURE REVIEWS NEUROSCIENCE

Generating Neuronal Diversity in the Mammalian Cerebral Cortex

(2015) Simona Lodato et al.   Annual Review of Cell and Developmental Biology

Modeling psychiatric disorders for developing effective treatments

(2015) Tobias Kaiser et al.   NATURE MEDICINE

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

Combinatorial labeling of single cells for gene expression cytometry

(2015) H. C. Fan et al.   SCIENCE

Single-cell-initiated monosynaptic tracing reveals layer-specific cortical network modules

(2015) A. Wertz et al.   SCIENCE

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Motor neurons and the generation of spinal motor neuron diversity

(2014) Nicolas Stifani   Frontiers in Cellular Neuroscience

In Vitro Generation of Neuromesodermal Progenitors Reveals Distinct Roles for Wnt Signalling in the Specification of Spinal Cord and Paraxial Mesoderm Identity

(2014) Mina Gouti et al.   PLOS BIOLOGY

Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells

(2013) M. W. Amoroso et al.   JOURNAL OF NEUROSCIENCE

Molecular logic of neocortical projection neuron specification, development and diversity

(2013) Luciano Custo Greig et al.   NATURE REVIEWS NEUROSCIENCE

Spatial organization of cortical and spinal neurons controlling motor behavior

(2012) Ariel J Levine et al.   CURRENT OPINION IN NEUROBIOLOGY

Cis-regulatory control of corticospinal system development and evolution

(2012) Sungbo Shim et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Intercellular (Mis)communication in Neurodegenerative Disease

(2012) Gwenn A. Garden et al.   NEURON

SnapShot: Spinal Cord Development

(2011) William A. Alaynick et al.   CELL

The Human Brain in a Dish: The Promise of iPSC-Derived Neurons

(2011) Ricardo Dolmetsch et al.   CELL

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

(2011) Sergiu P Paşca et al.   NATURE MEDICINE

Constructing and Deconstructing Stem Cell Models of Neurological Disease

(2011) Steve S.W. Han et al.   NEURON

Inhibition of Notch Signaling in Human Embryonic Stem Cell-Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and In Vivo

(2010) Lodovica Borghese et al.   STEM CELLS

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Circuits controlling vertebrate locomotion: moving in a new direction

(2009) Martyn Goulding   NATURE REVIEWS NEUROSCIENCE

Descending Pathways in Motor Control

(2008) Roger N. Lemon   Annual Review of Neuroscience

Spinal cord injury: plasticity, regeneration and the challenge of translational drug development

(2008) Armin Blesch et al.   TRENDS IN NEUROSCIENCES