Article
Geriatrics & Gerontology
Mu Niu, Zhikang Zhou, Long Wang, Jian Yang, Miao Sun, Xin Lv, Faqiang Zhang
Summary: This study investigated the longitudinal association between triglyceride-glucose index (TyG index) and the risk of myocardial injury post-stroke. The results showed that elevated TyG index was associated with an increased risk of myocardial injury, suggesting that TyG index may serve as a complementary approach for risk stratification in older patients with first-ever ischemic stroke and no prior cardiovascular comorbidities.
Article
Cardiac & Cardiovascular Systems
Bizhong Che, Chongke Zhong, Ruijie Zhang, Liyuan Pu, Tian Zhao, Yonghong Zhang, Liyuan Han
Summary: The triglyceride-glucose (TyG) index and triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio, two simple surrogate indicators of insulin resistance, are associated with an increased risk of cardiovascular disease (CVD) in European populations. The elevated risk is largely mediated by a higher prevalence of dyslipidemia, type 2 diabetes, and hypertension.
CARDIOVASCULAR DIABETOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Mohammad R. Akbar, Raymond Pranata, Arief Wibowo, Irvan, Teddy A. Sihite, Januar W. Martha
Summary: The study examined the relationship between TyG index and MACE in patients with ACS, showing that higher TyG index was associated with increased risk of MACE. Dose-response analysis indicated a non-linear relationship between TyG index and MACE.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Cardiac & Cardiovascular Systems
Li Liu, Zhenguo Wu, Yifan Zhuang, Yerui Zhang, Huiliang Cui, Fanghong Lu, Jie Peng, Jianmin Yang
Summary: This study found that the TyG index is associated with cardiovascular risk factors and can be used as a useful predictive marker for CVD and CHD risk in non-diabetic population.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Alfredo Caturano, Gaetana Albanese, Anna Di Martino, Carmine Coppola, Vincenzo Russo, Raffaele Galiero, Luca Rinaldi, Marcellino Monda, Raffaele Marfella, Ferdinando Carlo Sasso, Teresa Salvatore, Shaker A. Mousa
Summary: This study suggests that FLI>66 and pre-OLT smoking predict cardiovascular risk in adult OLT recipients.
Article
Biochemistry & Molecular Biology
Seungah Song, Da-Hye Son, Su-Jung Baik, Wan-Je Cho, Yong-Jae Lee
Summary: This study aimed to compare the usefulness of modified TyG indices for predicting NAFLD with the TyG index and FLI. The results showed that TyG-WC is a reliable indicator for the presence of NAFLD in Korean adults.
Article
Endocrinology & Metabolism
Su Zou, Chenxi Yang, Rui Shen, Xiang Wei, Junwen Gong, Yali Pan, Yang Lv, Yingjia Xu
Summary: The study found a significant association between the TyG index and the incidence of type 2 diabetes in participants with visceral fat obesity and/or fatty liver and normal BMI. Although there was a trend of the relationship between the TyG index and the incidence of type 2 diabetes in patients with BMI >= 25 mg/m(2), the relationship was no longer positive.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Susilane Pereira Araujo, Leidjaira Lopes Juvanhol, Josefina Bressan, Helen Hermana Miranda Hermsdorff
Summary: This study assessed the predictive capacity of the TyG index for cardiovascular risk and identified its cutoff point in a population at cardiometabolic risk. The results showed that the TyG index has a good predictive capacity and is positively associated with several cardiometabolic risk factors.
PREVENTIVE MEDICINE REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Ya-Wen Lu, Chun-Chin Chang, Ruey-Hsing Chou, Yi-Lin Tsai, Li-Kuo Liu, Liang-Kung Chen, Po-Hsun Huang, Shing-Jong Lin
Summary: The study explored the association between the TyG index and early subclinical atherosclerosis, finding a significant correlation between a high TyG index and atherosclerosis in non-diabetic patients, as well as gender disparities.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Clinical Neurology
Sangmo Hong, Kyungdo Han, Cheol-Young Park
Summary: This study using a large population dataset found an association between the TyG index and an increased risk of dementia, including AD and VD, independent of traditional cardiovascular risk factors, although the effect size of the TyG index was small.
ALZHEIMERS RESEARCH & THERAPY
(2021)
Article
Environmental Sciences
Maud Miguet, Sotirios Venetis, Gull Rukh, Lars Lind, Helgi B. Schioth
Summary: This study suggests that spending more than 3.5 hours outdoors per day is a risk factor for myocardial infarction and stroke. Further research is needed to better understand the relationship between time spent outdoors and cardiovascular diseases.
ENVIRONMENTAL RESEARCH
(2021)
Article
Nutrition & Dietetics
Rui Zhang, Jiahui Xu, Ruixue Li, Zhecong Yu, Wei Yuan, Hanshu Gao, Wenjing Feng, Cuiying Gu, Zhaoqing Sun, Liqiang Zheng
Summary: The study found an inverse association between serum SPD levels and the TyG index in the adult population, suggesting that higher SPD levels are associated with a decreased risk of insulin resistance.
Article
Public, Environmental & Occupational Health
Jiangbo Wang, Shiru Zhang, Yundi Jiao, Liqiang Zheng, Yingxian Sun, Zhaoqing Sun
Summary: In Chinese rural adults, cumulative blood pressure showed a stronger association with cardiovascular disease incidence compared to current blood pressure. Additionally, cumulative blood pressure slightly improved the predictive performance for cardiovascular disease. These findings highlight the incremental predictive value of cumulative blood pressure in cardiovascular disease risk assessment among Chinese rural adults.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Clinical Neurology
Gad Abraham, Loes Rutten-Jacobs, Michael Inouye
Summary: Genetic factors play a significant role in the prediction of cardiovascular diseases, including stroke, and the development of polygenic risk scores has shown potential to improve risk prediction for stroke.
Article
Cardiac & Cardiovascular Systems
Yang Ling, Cong Fu, Qun Fan, Jichun Liu, Ling Jiang, Shengxing Tang
Summary: The TyG index serves as an independent predictor of NOAF during hospitalization and indicates a poorer prognosis after a relatively long-term follow-up.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Hee Sun Kim, Heejin Lee, Sherlyn Mae P. Provido, Minji Kang, Grace H. Chung, Sangmo Hong, Sung Hoon Yu, Chang Beom Lee, Jung Eun Lee
Summary: The study found that greater dietary diversity was associated with a lower prevalence of abdominal obesity in Filipino immigrant women. On the other hand, proinflammatory scores based on diet and lifestyle factors were positively associated with an increased prevalence of dyslipidemia and insulin resistance.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Health Care Sciences & Services
Hyung-Suk Kim, Kyueng-Whan Min, Dong-Hoon Kim, Byoung-Kwan Son, Mi-Jung Kwon, Sang-Mo Hong
Summary: High expression of WHSC1L1 is associated with poor prognosis and immune cell proportions in breast cancer patients. WHSC1L1 may play a role in breast cancer development by regulating the lymphocyte apoptotic process. The GBM model with WHSC1L1 shows improved prognostic performance.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Endocrinology & Metabolism
Cheol Ryong Ku, Kyong Yeun Jung, Chang Ho Ahn, Jun Sung Moon, Ju Hee Lee, Eun Heui Kim, Hyemi Kwon, Hee Kyung Kim, Sunghwan Suh, Sangmo Hong, Jeonghoon Ha, Eun Roh, Jin Hwa Kim, Mi-kyung Kim
Summary: Efforts to discover an efficacious vaccine against COVID-19 have been ongoing since the first outbreak, with mRNA and DNA vaccines being administered in most countries. The side effects of these vaccines and their effects on the clinical course of COVID-19 are influenced by patients' health status and endocrine disorders. Clinical specialists' position statements are crucial in providing appropriate recommendations based on medical evidence and clinical experience in the current severe circumstances of the pandemic.
ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Cardiac & Cardiovascular Systems
Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
Summary: Patients with acromegaly have a higher risk for atrial fibrillation, congestive heart failure, and all-cause death, with a time-dependent association between atrial fibrillation and acromegaly.
EUROPEAN HEART JOURNAL
(2022)
Article
Endocrinology & Metabolism
Sangmo Hong, Jung Hwan Park, Kyungdo Han, Chang Beom Lee, Dong Sun Kim, Sung Hoon Yu
Summary: Elderly patients with T2DM and obesity have better clinical outcomes compared to normal-weight patients. Waist circumference (WC) is a suitable indicator for assessing obesity-related risks in these patients.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Sangmo Hong, Chang Hee Jung, Song Han, Cheol-Young Park
Summary: This study found that the reduction of HbA1c by DPP-4 inhibitors is associated with increasing age, and this association is linked with higher DPP-4 inhibition.
DIABETES & METABOLISM JOURNAL
(2022)
Article
Public, Environmental & Occupational Health
Akinkunmi Paul Okekunle, Heejin Lee, Sherlyn Mae P. Provido, Grace H. Chung, Sangmo Hong, Sung Hoon Yu, Chang Beom Lee, Jung Eun Lee
Summary: This study examined the association between dietary intake of branched-chain amino acids (BCAA) and the risk of obesity among immigrant Filipino women in Korea. The findings suggest a potential inverse association between higher BCAA intake and the risk of obesity, particularly among non-smokers.
Article
Endocrinology & Metabolism
Sangmo Hong, Woo Je Lee, Cheol-Young Park
Summary: The antiplatelet effects of aspirin and cilostazol differ in patients with diabetes, with aspirin showing better results. However, cilostazol has favorable effects on atherogenic dyslipidemia.
ENDOCRINOLOGY AND METABOLISM
(2022)
Article
Health Care Sciences & Services
Kyung-Soo Kim, Sangmo Hong, You-Cheol Hwang, Hong-Yup Ahn, Cheol-Young Park
Summary: The TyG index is associated with an increased risk of all-cause and cardiovascular mortality, especially in women. However, in men, the TyG index is associated with a decreased risk of all-cause mortality. The association between the TyG index and cardiovascular mortality is not statistically significant in either men or women.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Kyung-Soo Kim, Sangmo Hong, Hong-Yup Ahn, Cheol-Young Park
Summary: This study found that the TyG index is a simple and easy-to-calculate marker associated with NAFLD. Long-term observation showed a positive association between TyG index and the risk of NAFLD, with the risk starting to increase at around 8.24.
Article
Clinical Neurology
Sangmo Hong, Kyungdo Han, Kyung-Soo Kim, Cheol-Young Park
Summary: This study found an association between acromegaly and neurodegenerative diseases such as Parkinson's disease and dementia. It also suggests that IGF-1/growth hormone level may be related to neurodegenerative diseases.
Article
Endocrinology & Metabolism
Kyung-Soo Kim, Sangmo Hong, Kyungdo Han, Cheol-Young Park
Summary: This study investigated the effects of fenofibrate add-on to statin treatment on all-cause death and cardiovascular disease (CVD) in the general population with high triglyceride (TG) levels. The research found that the use of fenofibrate was associated with a lower incidence of all-cause death and CVD in individuals with high TG, regardless of the presence of diabetes. However, the beneficial effects required at least one year of fenofibrate use.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2022)
Article
Cardiac & Cardiovascular Systems
Heejin Lee, Hyojin Kim, Sherlyn Mae P. Provido, Minji Kang, Grace H. Chung, Jae W. Lee, Sangmo Hong, Sung Hoon Yu, Chang Beom Lee, Jung Eun Lee
Summary: This study found that high dietary intake of saturated fatty acids (SFA) was significantly associated with a high prevalence of dyslipidemia in Filipino immigrant women in Korea. These results highlight the importance of dietary fat intake and the need for further research to determine risk factors for cardiovascular disease in Southeast Asian populations.
Article
Endocrinology & Metabolism
Shinje Moon, Sangmo Hong, Kyungdo Han, Cheol-Young Park
Summary: Using the Korean National Health Information Database (NHID), the study found that patients with acromegaly who did not receive treatment had a higher risk of depression compared to controls. Untreated acromegaly patients should be closely monitored for the development of depression, especially in the early years after diagnosis.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Urology & Nephrology
Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
Summary: This study investigated the risk of end-stage kidney disease (ESKD) in patients with acromegaly and found a significantly higher risk compared to controls. Diabetes and hypertension were identified as significant factors mediating the association between acromegaly and ESKD.
KIDNEY INTERNATIONAL
(2023)