Pinpointing miRNA and genes enrichment over trait-relevant tissue network in Genome-Wide Association Studies

Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies

(2020) Lulu Shang et al.   PLoS Genetics

Systemic lupus erythematosus in a girl with PTEN variant and transaldolase deficiency: a novel phenotype

(2020) Sulaiman M. Al-Mayouf et al.   CLINICAL RHEUMATOLOGY

PTEN in Autism and Neurodevelopmental Disorders

(2019) Sebastian Rademacher et al.   Cold Spring Harbor Perspectives in Medicine

PTEN negatively regulates the expression of pro-inflammatory cytokines and chemokines of fibroblast-like synoviocytes in adjuvant-induced arthritis

(2019) Xiao-Feng Li et al.   Artificial Cells Nanomedicine and Biotechnology

Identifying Interaction Clusters for MiRNA and MRNA Pairs in TCGA Network

(2019) Dai et al.   Genes

Identifying and exploiting trait-relevant tissues with multiple functional annotations in genome-wide association studies

(2018) Xingjie Hao et al.   PLoS Genetics

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

(2018) Jacob O'Brien et al.   Frontiers in Endocrinology

Analysis of PTEN expression and promoter methylation in Uyghur patients with mild type 2 diabetes mellitus

(2018) Liang Yin et al.   MEDICINE

Integration of genetics and miRNA–target gene network identified disease biology implicated in tissue specificity

(2018) Saori Sakaue et al.   NUCLEIC ACIDS RESEARCH

Inhibition of PTEN Attenuates Endoplasmic Reticulum Stress and Apoptosis via Activation of PI3K/AKT Pathway in Alzheimer’s Disease

(2017) Weigang Cui et al.   NEUROCHEMICAL RESEARCH

SNPs in microRNA target sites and their potential role in human disease

(2017) Adrianna Moszyńska et al.   Open Biology

Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer’s disease

(2017) Qiongshi Lu et al.   PLoS Genetics

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

Competing endogenous RNA networks in human cancer: hypothesis, validation, and perspectives

(2016) Chao Yang et al.   Oncotarget

Significant impact of miRNA–target gene networks on genetics of human complex traits

(2016) Yukinori Okada et al.   Scientific Reports

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

PI3K/AKT/PTEN pathway as a target for Crohn’s disease therapy (Review)

(2014) NANA TOKUHIRA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Emerging Roles of Competing Endogenous RNAs in Cancer: Insights from the Regulation of PTEN

(2013) A. de Giorgio et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of DU145 prostate cancer cell growth by Scm-like with four mbt domains 2

(2012) Kwanghyun Lee et al.   JOURNAL OF BIOSCIENCES

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein

(2010) Peiying Ye et al.   Protein & Cell

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Primary Biliary Cirrhosis Is Associated With a Genetic Variant in the 3′ Flanking Region of the CTLA4 Gene

(2008) Brian D. Juran et al.   GASTROENTEROLOGY

ASAP3 Is a Focal Adhesion-associated Arf GAP That Functions in Cell Migration and Invasion

(2008) Vi Luan Ha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues

(2007) Anastasia Kuzmin et al.   GENE EXPRESSION PATTERNS