Terminal deoxynucleotidyl transferase combined CRISPR-Cas12a amplification strategy for ultrasensitive detection of uracil-DNA glycosylase with zero background

An enzyme-free and substrate-free electrochemical biosensor with robust porphyrin-based covalent-linked nanomaterial as nanoelectrocatalyst and efficient support for sensitive detection of uracil-DNA glycosylase

(2020) Tingting Liu et al.   BIOSENSORS & BIOELECTRONICS

Naked-Eye Detection of Grapevine Red-Blotch Viral Infection Using a Plasmonic CRISPR Cas12a Assay

(2019) Yongya Li et al.   ANALYTICAL CHEMISTRY

Cas12aVDet: A CRISPR/Cas12a-Based Platform for Rapid and Visual Nucleic Acid Detection

(2019) Bei Wang et al.   ANALYTICAL CHEMISTRY

Exploring the Trans-Cleavage Activity of CRISPR-Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor

(2019) Yifan Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Coupling photoelectrochemical and electrochemical strategies in one probe electrode: Toward sensitive and reliable dual-signal bioassay for uracil-DNA glycosylase activity

(2019) Yanwei Lu et al.   BIOSENSORS & BIOELECTRONICS

Low-background electrochemical biosensor for one-step detection of base excision repair enzyme

(2019) Min-hui Zhao et al.   BIOSENSORS & BIOELECTRONICS

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

(2019) Mindong Liang et al.   Nature Communications

Magnetic bead-gold nanoparticle hybrids probe based on optically countable gold nanoparticles with dark-field microscope for T4 polynucleotide kinase activity assay

(2019) Tian Jin et al.   BIOSENSORS & BIOELECTRONICS

Terminal deoxynucleotidyl transferase-activated nicking enzyme amplification reaction for specific and sensitive detection of DNA methyltransferase and polynucleotide kinase

(2019) Yi-Chen Du et al.   BIOSENSORS & BIOELECTRONICS

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic-Acid Targets

(2019) Ying Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Dual-Enzyme-Assisted Three-Dimensional DNA Walking Machine Using T4 Polynucleotide Kinase as Activators and Application in Polynucleotide Kinase Assays

(2018) Chang Feng et al.   ANALYTICAL CHEMISTRY

Terminal Deoxynucleotidyl Transferase and T7 Exonuclease-Aided Amplification Strategy for Ultrasensitive Detection of Uracil-DNA Glycosylase

(2018) Yi-Chen Du et al.   ANALYTICAL CHEMISTRY

An ultrasensitive electrochemical biosensor for polynucleotide kinase assay based on gold nanoparticle-mediated lambda exonuclease cleavage-induced signal amplification

(2018) Lin Cui et al.   BIOSENSORS & BIOELECTRONICS

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

Label-free and ultrasensitive detection of polynucleotide kinase activity at the single-cell level

(2018) Meng Liu et al.   CHEMICAL COMMUNICATIONS

Kinetic Mechanism of DNA Polymerases: Contributions of Conformational Dynamics and a Third Divalent Metal Ion

(2018) Austin T. Raper et al.   CHEMICAL REVIEWS

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

CRISPR-Cas12a-assisted nucleic acid detection

(2018) Shi-Yuan Li et al.   Cell Discovery

Label-free thioflavin T/G-quadruplex-based real-time strand displacement amplification for biosensing applications

(2016) Yi-Chen Du et al.   BIOSENSORS & BIOELECTRONICS

Optimization of strand displacement amplification-sensitized G-quadruplex DNAzyme-based sensing system and its application in activity detection of uracil-DNA glycosylase

(2016) Yi-Chen Du et al.   BIOSENSORS & BIOELECTRONICS

Water-mediated changes in the quaternary structure of hemoglobin

(2015) P.S. Kaushal et al.   ACTA CRYSTALLOGRAPHICA SECTION A

Uracil DNA Glycosylase Activity on Nucleosomal DNA Depends on Rotational Orientation of Targets

(2009) Hope A. Cole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uracil-DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognition

(2009) Dmitry O. Zharkov et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS