Structure activity relationship of novel antiviral nucleosides against Enterovirus A71

Novel coronavirus treatment with ribavirin: Groundwork for an evaluation concerning COVID-19

(2020) Jahan S. Khalili et al.   JOURNAL OF MEDICAL VIROLOGY

Drug repurposing of pyrimidine analogs as potent antiviral compounds against human enterovirus A71 infection with potential clinical applications

(2020) Jialei Sun et al.   Scientific Reports

Design and in Vivo Characterization of A1 Adenosine Receptor Agonists in the Native Ribose and Conformationally Constrained (N)-Methanocarba Series

(2019) Dilip K. Tosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Scaffold Simplification Strategy Leads to a Novel Generation of Dual Human Immunodeficiency Virus and Enterovirus-A71 Entry Inhibitors

(2019) Belén Martínez-Gualda et al.   JOURNAL OF MEDICINAL CHEMISTRY

Outcomes following severe hand foot and mouth disease: A systematic review and meta-analysis

(2018) Eben Jones et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Enterovirus D68 and acute flaccid myelitis—evaluating the evidence for causality

(2018) Kevin Messacar et al.   LANCET INFECTIOUS DISEASES

Fluorination of Naturally Occurring N6-Benzyladenosine Remarkably Increased Its Antiviral Activity and Selectivity

(2017) Vladimir Oslovsky et al.   MOLECULES

Direct-acting antivirals and host-targeting strategies to combat enterovirus infections

(2017) Lisa Bauer et al.   Current Opinion in Virology

Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds

(2016) Donald F. Smee et al.   ANTIVIRAL RESEARCH

Modification of the length and structure of the linker of N6-benzyladenosine modulates its selective antiviral activity against enterovirus 71

(2016) Mikhail S. Drenichev et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

South (S)- and North (N)-Methanocarba-7-Deazaadenosine Analogues as Inhibitors of Human Adenosine Kinase

(2016) Kiran S. Toti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT2B/5HT2C Serotonin Receptor Antagonists

(2016) Dilip K. Tosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antivirals against enteroviruses: a critical review from a public health perspective

(2015) Kimberley SM Benschop et al.   ANTIVIRAL THERAPY

Chemical modification of the plant isoprenoid cytokinin N6-isopentenyladenosine yields a selective inhibitor of human enterovirus 71 replication

(2015) Vitali I. Tararov et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Development of antiviral agents toward enterovirus 71 infection

(2015) Hamid Reza Pourianfar et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Replication and Inhibitors of Enteroviruses and Parechoviruses

(2015) Lonneke Linden et al.   Viruses-Basel

An adenosine nucleoside analogue NITD008 inhibits EV71 proliferation

(2014) Luqing Shang et al.   ANTIVIRAL RESEARCH

Efficacy, Safety, and Immunogenicity of an Enterovirus 71 Vaccine in China

(2014) Fengcai Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiviral drug discovery for the treatment of enterovirus 71 infections

(2012) Luqing Shang et al.   ANTIVIRAL RESEARCH

Structural Sweet Spot for A1 Adenosine Receptor Activation by Truncated (N)-Methanocarba Nucleosides: Receptor Docking and Potent Anticonvulsant Activity

(2012) Dilip K. Tosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8′-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents

(2012) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribavirin-Resistant Mutants of Human Enterovirus 71 Express a High Replication Fidelity Phenotype during Growth in Cell Culture

(2012) Sara Sadeghipour et al.   JOURNAL OF VIROLOGY

Automated design of ligands to polypharmacological profiles

(2012) Jérémy Besnard et al.   NATURE

Crystal Structure of Human Enterovirus 71

(2012) P. Plevka et al.   SCIENCE

Cellular Receptors for Human Enterovirus Species A

(2012) Yorihiro Nishimura et al.   Frontiers in Microbiology

Combating enterovirus replication: State-of-the-art on antiviral research

(2011) Hendrik Jan Thibaut et al.   BIOCHEMICAL PHARMACOLOGY

Truncated (N)-Methanocarba Nucleosides as A1 Adenosine Receptor Agonists and Partial Agonists: Overcoming Lack of a Recognition Element

(2011) Dilip K. Tosh et al.   ACS Medicinal Chemistry Letters

Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity

(2008) M. Arita et al.   JOURNAL OF GENERAL VIROLOGY