The implication of long non-coding RNAs in the diagnosis, pathogenesis and drug resistance of pancreatic ductal adenocarcinoma and their possible therapeutic potential
出版年份 2020 全文链接
标题
The implication of long non-coding RNAs in the diagnosis, pathogenesis and drug resistance of pancreatic ductal adenocarcinoma and their possible therapeutic potential
作者
关键词
Pancreatic ductal adenocarcinoma (PDAC), Long non-coding RNA (lncRNA), CRISPR-Cas9, KRAS, Antisense oligonucleotides
出版物
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Volume 1874, Issue 2, Pages 188423
出版商
Elsevier BV
发表日期
2020-08-30
DOI
10.1016/j.bbcan.2020.188423
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The multifaceted roles of long noncoding RNAs in pancreatic cancer: an update on what we know
- (2020) Wenjia Zhou et al. Cancer Cell International
- Deciphering the Mounting Complexity of the p53 Regulatory Network in Correlation to Long Non-Coding RNAs (lncRNAs) in Ovarian Cancer
- (2020) Sonali Pal et al. Cells
- Non-coding RNAs in Pancreatic Ductal Adenocarcinoma
- (2020) Ruining Gong et al. Frontiers in Oncology
- Mechanistic Involvement of Long Non-Coding RNAs in Oncotherapeutics Resistance in Triple-Negative Breast Cancer
- (2020) Samarth Kansara et al. Cells
- LncRNA TP73-AS1 sponges miR-141-3p to promote the migration and invasion of pancreatic cancer cells through the upregulation of BDH2
- (2019) Xian-ping Cui et al. BIOSCIENCE REPORTS
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- High Expression of Long Noncoding RNA HOTAIRM1 is Associated with the Proliferation and Migration in Pancreatic Ductal Adenocarcinoma
- (2019) Yongyun Luo et al. PATHOLOGY & ONCOLOGY RESEARCH
- Targeted design and identification of AC1NOD4Q to block activity of HOTAIR by abrogating the scaffold interaction with EZH2
- (2019) Yu Ren et al. Clinical Epigenetics
- LncRNA SNHG7 promotes pancreatic cancer proliferation through ID4 by sponging miR-342-3p
- (2019) Dongfeng Cheng et al. Cell and Bioscience
- Chemotherapy for pancreatic cancer
- (2019) Christoph Springfeld et al. PRESSE MEDICALE
- Long non-coding RNA LINC00346 promotes pancreatic cancer growth and gemcitabine resistance by sponging miR-188-3p to derepress BRD4 expression
- (2019) Weidong Shi et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The expanding roles of long non-coding RNAs in the regulation of cancer stem cells
- (2019) Zhaowu Ma et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- LncRNA SNHG16 promotes tumor growth of pancreatic cancer by targeting miR-218-5p
- (2019) Songyang Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- LncRNA XIST enhanced TGF-β2 expression by targeting miR-141-3p to promote pancreatic cancer cells invasion
- (2019) Jianmin Sun et al. BIOSCIENCE REPORTS
- lncRNA TP53TG1 promotes pancreatic ductal adenocarcinoma development by acting as a molecular sponge of miR‐96
- (2019) Yufeng Zhang et al. CANCER SCIENCE
- LncRNA SNHG14 potentiates pancreatic cancer progression via modulation of annexin A2 expression by acting as a competing endogenous RNA for miR‐613
- (2019) Peng‐cheng Deng et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression
- (2019) Jiayan Yan et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription
- (2019) Wan-Xin Peng et al. ONCOGENE
- Insights into Biological Role of LncRNAs in Epithelial-Mesenchymal Transition
- (2019) Jun-Ting Cheng et al. Cells
- Long non-coding SBF2-AS1 acting as a competing endogenous RNA to sponge microRNA-142-3p to participate in gemcitabine resistance in pancreatic cancer via upregulating TWF1
- (2019) Yong-Qiang Hua et al. Aging-US
- Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway
- (2019) Shan Lei et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Long noncoding RNA LINC01111 suppresses pancreatic cancer aggressiveness by regulating DUSP1 expression via microRNA-3924
- (2019) Shutao Pan et al. Cell Death & Disease
- Circulating extracellular vesicle‐encapsulated HULC is a potential biomarker for human pancreatic cancer
- (2019) Kenji Takahashi et al. CANCER SCIENCE
- Long non-coding RNA HULC as a diagnostic and prognostic marker of pancreatic cancer
- (2019) Zheng-Lin Ou et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Five key lncRNAs considered as prognostic targets for predicting pancreatic ductal adenocarcinoma
- (2018) Jukun Song et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- LncRNA TUG1 promoted viability and associated with gemcitabine resistant in pancreatic ductal adenocarcinoma
- (2018) Fan Yang et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3
- (2018) Hao Hu et al. Molecular Cancer
- LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis
- (2018) Fengting Huang et al. Molecular Cancer
- Therapeutic Targeting of Long Non-Coding RNAs in Cancer
- (2018) Gayatri Arun et al. TRENDS IN MOLECULAR MEDICINE
- Long noncoding RNA PANDAR blocks CDKN1A gene transcription by competitive interaction with p53 protein in gastric cancer
- (2018) Jun Liu et al. Cell Death & Disease
- Organoid profiling identifies common responders to chemotherapy in pancreatic cancer
- (2018) Hervé Tiriac et al. Cancer Discovery
- Application of CRISPR/Cas9 for Long non-coding RNA genes in Cancer Research
- (2018) shuai zhen et al. HUMAN GENE THERAPY
- MEG8 long noncoding RNA contributes to epigenetic progression of the epithelial-mesenchymal transition of lung and pancreatic cancer cells
- (2018) Minoru Terashima et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Long Noncoding RNA TUG1/miR-29c Axis Affects Cell Proliferation, Invasion, and Migration in Human Pancreatic Cancer
- (2018) Yebin Lu et al. DISEASE MARKERS
- LncRNA H19/miR-194/PFTK1 axis modulates the cell proliferation and migration of pancreatic cancer
- (2018) Yunpeng Sun et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Gemcitabine exhibits a suppressive effect on pancreatic cancer cell growth by regulating processing of PVT1 to miR1207
- (2018) Lei You et al. Molecular Oncology
- lncRNA GAS5 Reverses EMT and Tumor Stem Cell-Mediated Gemcitabine Resistance and Metastasis by Targeting miR-221/SOCS3 in Pancreatic Cancer
- (2018) Bingyan Liu et al. Molecular Therapy-Nucleic Acids
- The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis-inducing ligand
- (2017) Shan-zhong Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Linc00511 acts as a competing endogenous RNA to regulate VEGFA expression through sponging hsa-miR-29b-3p in pancreatic ductal adenocarcinoma
- (2017) Xiaohui Zhao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets
- (2017) Deepika Kanojia et al. Journal of Hematology & Oncology
- The long non-coding RNA BC200 (BCYRN1) is critical for cancer cell survival and proliferation
- (2017) Evan P. Booy et al. Molecular Cancer
- Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer
- (2017) Wan-xin Peng et al. Molecular Cancer
- A novel mechanism of lncRNA and miRNA interaction: CCAT2 regulates miR-145 expression by suppressing its maturation process in colon cancer cells
- (2017) Yingjie Yu et al. Molecular Cancer
- Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer
- (2017) Hongzhe Li et al. Molecular Cancer
- Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells
- (2017) Yuran Gao et al. Cell Death & Disease
- LncRNA AK023948 is a positive regulator of AKT
- (2017) Pratirodh Koirala et al. Nature Communications
- The lncRNA MALAT1 acts as a competing endogenous RNA to regulate KRAS expression by sponging miR-217 in pancreatic ductal adenocarcinoma
- (2017) Pingping Liu et al. Scientific Reports
- Linc-ing Circulating Long Non-coding RNAs to the Diagnosis and Malignant Prediction of Intraductal Papillary Mucinous Neoplasms of the Pancreas
- (2017) Jennifer B. Permuth et al. Scientific Reports
- Cancer statistics in China, 2015
- (2016) Wanqing Chen et al. CA-A CANCER JOURNAL FOR CLINICIANS
- The long noncoding RNA H19 promotes cell proliferation via E2F-1 in pancreatic ductal adenocarcinoma
- (2016) Ling Ma et al. CANCER BIOLOGY & THERAPY
- Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis
- (2016) Chenggang Li et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Long non-coding RNA LOC389641 promotes progression of pancreatic ductal adenocarcinoma and increases cell invasion by regulating E-cadherin in a TNFRSF10A-related manner
- (2016) Shangyou Zheng et al. CANCER LETTERS
- LincRNA-ROR promotes invasion, metastasis and tumor growth in pancreatic cancer through activating ZEB1 pathway
- (2016) Han-xiang Zhan et al. CANCER LETTERS
- EZH2 coupled with HOTAIR to silence MicroRNA-34a by the induction of heterochromatin formation in human pancreatic ductal adenocarcinoma
- (2016) Chi-Han Li et al. INTERNATIONAL JOURNAL OF CANCER
- The bright side of dark matter: lncRNAs in cancer
- (2016) Joseph R. Evans et al. JOURNAL OF CLINICAL INVESTIGATION
- Pancreatic cancer
- (2016) Terumi Kamisawa et al. LANCET
- Regulation of alternative splicing of Bcl-x by BC200 contributes to breast cancer pathogenesis
- (2016) R Singh et al. Cell Death & Disease
- Hypoxia-induced lncRNA-NUTF2P3-001 contributes to tumorigenesis of pancreatic cancer by derepressing the miR-3923/KRAS pathway
- (2016) Xiang Li et al. Oncotarget
- Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer
- (2016) Le Li et al. Oncotarget
- Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer
- (2016) Shuai Zhen et al. Oncotarget
- Analysis of long non-coding RNA expression profiles in pancreatic ductal adenocarcinoma
- (2016) Xue-Liang Fu et al. Scientific Reports
- Morpholinos: Antisense and Sensibility
- (2015) Martin Blum et al. DEVELOPMENTAL CELL
- Differentiation of mammary tumors and reduction in metastasis uponMalat1lncRNA loss
- (2015) Gayatri Arun et al. GENES & DEVELOPMENT
- Epidemiology of Pancreatic and Periampullary Cancer
- (2015) Prabin Thapa Indian Journal of Surgery
- Long Noncoding RNA MALAT-1 Enhances Stem Cell-Like Phenotypes in Pancreatic Cancer Cells
- (2015) Feng Jiao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- High expression of AFAP1-AS1 is associated with poor survival and short-term recurrence in pancreatic ductal adenocarcinoma
- (2015) Yibiao Ye et al. Journal of Translational Medicine
- The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer
- (2015) Zhihua Li et al. Journal of Translational Medicine
- Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer
- (2015) Sören Müller et al. Molecular Cancer
- Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides
- (2015) Kim A. Lennox et al. NUCLEIC ACIDS RESEARCH
- Long noncoding RNA MIR31HG exhibits oncogenic property in pancreatic ductal adenocarcinoma and is negatively regulated by miR-193b
- (2015) H Yang et al. ONCOGENE
- The long non-coding RNA HOTAIR affects the radiosensitivity of pancreatic ductal adenocarcinoma by regulating the expression of Wnt inhibitory factor 1
- (2015) Yanhui Jiang et al. TUMOR BIOLOGY
- Expression profile of long non-coding RNAs in pancreatic cancer and their clinical significance as biomarkers
- (2015) Yingxue Wang et al. Oncotarget
- ROR functions as a ceRNA to regulate Nanog expression by sponging miR-145 and predicts poor prognosis in pancreatic cancer
- (2015) Song Gao et al. Oncotarget
- Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells
- (2015) Wenwen Chien et al. Oncotarget
- LAMC2 as a therapeutic target for cancers
- (2014) Manoj Garg et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Long non-coding RNAs expressed in pancreatic ductal adenocarcinoma and lncRNA BC008363 an independent prognostic factor in PDAC
- (2014) Jiao Li et al. PANCREATOLOGY
- Exploring the Wnt Pathway-Associated LncRNAs and Genes Involved in Pancreatic Carcinogenesis Driven by Tp53 Mutation
- (2014) Qi Wang et al. PHARMACEUTICAL RESEARCH
- Downregulation of gas5 increases pancreatic cancer cell proliferation by regulating CDK6
- (2013) Xiongxiong Lu et al. CELL AND TISSUE RESEARCH
- Laminin, gamma 2 (LAMC2): A Promising New Putative Pancreatic Cancer Biomarker Identified by Proteomic Analysis of Pancreatic Adenocarcinoma Tissues
- (2013) Hari Kosanam et al. MOLECULAR & CELLULAR PROTEOMICS
- Induced DNA demethylation can reshape chromatin topology at the IGF2-H19 locus
- (2013) Yoko Ito et al. NUCLEIC ACIDS RESEARCH
- Mutant KRAS is a druggable target for pancreatic cancer
- (2013) E. Zorde Khvalevsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome Regulation by Long Noncoding RNAs
- (2012) John L. Rinn et al. Annual Review of Biochemistry
- Phase 1/2a, dose-escalation, safety, pharmacokinetic and preliminary efficacy study of intratumoral administration of BC-819 in patients with unresectable pancreatic cancer
- (2012) N Hanna et al. CANCER GENE THERAPY
- The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells
- (2012) T. Gutschner et al. CANCER RESEARCH
- HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer
- (2012) K Kim et al. ONCOGENE
- Genome-wide screen identifies PVT1 as a regulator of Gemcitabine sensitivity in human pancreatic cancer cells
- (2011) Lei You et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer
- (2011) Ana C Tahira et al. Molecular Cancer
- PIWI-interacting small RNAs: the vanguard of genome defence
- (2011) Mikiko C. Siomi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- RNAi mechanisms and applications
- (2008) Daniel H. Kim et al. BIOTECHNIQUES
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started