MRP5 nitration by NO-releasing gemcitabine encapsulated in liposomes confers sensitivity in chemoresistant pancreatic adenocarcinoma cells

Coencapsulation of disulfiram and doxorubicin in liposomes strongly reverses multidrug resistance in breast cancer cells

(2020) Francesca Rolle et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts

(2019) Elena Gazzano et al.   CANCER LETTERS

Novel discoveries targeting gemcitabine‐based chemoresistance and new therapies in pancreatic cancer: How far are we from the destination?

(2019) Wenhao Luo et al.   Cancer Medicine

Protein tyrosine nitration in lung cancer: current research status and future perspectives

(2018) Xianquan Zhan et al.   CURRENT MEDICINAL CHEMISTRY

A Multiplex Enzymatic Machinery for Cellular Protein S-nitrosylation

(2018) Divya Seth et al.   MOLECULAR CELL

Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration

(2018) Silvina Bartesaghi et al.   Redox Biology

Nitric Oxide Donor-Based Cancer Therapy: Advances and Prospects

(2017) Zhangjian Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Light-Regulated NO Release as a Novel Strategy To Overcome Doxorubicin Multidrug Resistance

(2017) Konstantin Chegaev et al.   ACS Medicinal Chemistry Letters

Suppression of pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer to gemcitabine and 5FU, and inhibits the formation of pancreatic cancer stem like cells

(2017) Jae Hee Cho et al.   Oncotarget

Pancreatic Cancer Chemoresistance to Gemcitabine

(2017) Manoj Amrutkar et al.   Cancers

Molecular mechanisms for tumour resistance to chemotherapy

(2016) Shu-Ting Pan et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems

(2016) Silvia Arpicco et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Nitric oxide synthetic pathway and cGMP levels are altered in red blood cells from end-stage renal disease patients

(2016) Natalia Di Pietro et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner

(2015) Claudia Fiorini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine

(2015) Claudia Fiorini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Time and concentration dependency of P-gp, MRP1 and MRP5 induction in response to gemcitabine uptake in Capan-2 pancreatic cancer cells

(2015) Hamed Gilzad Kohan et al.   XENOBIOTICA

Regulation of Bim in Health and Disease

(2015) Ronit Vogt Sionov et al.   Oncotarget

Interdependence of Gemcitabine Treatment, Transporter Expression, and Resistance in Human Pancreatic Carcinoma Cells

(2015) Wolfgang Hagmann et al.   NEOPLASIA

Liposomal Nitrooxy-Doxorubicin: One Step over Caelyx in Drug-Resistant Human Cancer Cells

(2014) Isabella Pedrini et al.   MOLECULAR PHARMACEUTICS

Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity

(2013) Elisa Dalla Pozza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Hyaluronic acid-coated liposomes for active targeting of gemcitabine

(2013) Silvia Arpicco et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Peroxynitrite, a Stealthy Biological Oxidant

(2013) Rafael Radi   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine

(2012) Elisa Dalla Pozza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hematite Nanoparticles Larger than 90 nm Show No Sign of Toxicity in Terms of Lactate Dehydrogenase Release, Nitric Oxide Generation, Apoptosis, and Comet Assay in Murine Alveolar Macrophages and Human Lung Epithelial Cells

(2012) Francesca Stefania Freyria et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease

(2012) Puneet Anand et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Gemcitabine response in pancreatic adenocarcinoma cells is synergistically enhanced by dithiocarbamate derivatives

(2011) Elisa Dalla Pozza et al.   FREE RADICAL BIOLOGY AND MEDICINE

The effects of Gemcitabine and Vinorelbine on inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) distribution of MCF-7 breast cancer cells

(2009) Naciye Dilara Zeybek et al.   ACTA HISTOCHEMICA

(Nitrooxyacyloxy)methyl Esters of Aspirin as Novel Nitric Oxide Releasing Aspirins

(2009) Loretta Lazzarato et al.   JOURNAL OF MEDICINAL CHEMISTRY

iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells

(2009) Sara De Boo et al.   Molecular Cancer

Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins

(2008) J. D. Young et al.   XENOBIOTICA