Lysosomal targeting of autophagosomes by the TECPR domain of TECPR2

TECPR1 promotes aggrephagy by direct recruitment of LC3C autophagosomes to lysosomes

(2020) Lisa Wetzel et al.   Nature Communications

A tecpr2 knockout mouse exhibits age-dependent neuroaxonal dystrophy associated with autophagosome accumulation

(2020) Bat-Chen Tamim-Yecheskel et al.   Autophagy

Autophagosome-Lysosome Fusion

(2019) Péter Lőrincz et al.   JOURNAL OF MOLECULAR BIOLOGY

Coordination of Autophagosome–Lysosome Fusion by Atg8 Family Members

(2018) Franziska Kriegenburg et al.   CURRENT BIOLOGY

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

(2017) Fiona M. Menzies et al.   NEURON

TECPR2 mutations cause a new subtype of familial dysautonomia like hereditary sensory autonomic neuropathy with intellectual disability

(2016) Gali Heimer et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes

(2016) Zheng Wang et al.   MOLECULAR CELL

Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism

(2015) Darius Ebrahimi-Fakhari et al.   BRAIN

TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export

(2015) Daniela Stadel et al.   MOLECULAR CELL

PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

(2015) David G. McEwan et al.   MOLECULAR CELL

TECPR2 Associated Neuroaxonal Dystrophy in Spanish Water Dogs

(2015) Kerstin Hahn et al.   PLoS One

The C. elegans LC3 Acts Downstream of GABARAP to Degrade Autophagosomes by Interacting with the HOPS Subunit VPS39

(2014) Marion Manil-Ségalen et al.   DEVELOPMENTAL CELL

Getting ready for building: signaling and autophagosome biogenesis

(2014) A. Abada et al.   EMBO REPORTS

Defective autophagy in spastizin mutated patients with hereditary spastic paraparesis type 15

(2013) Chiara Vantaggiato et al.   BRAIN

Mutation in TECPR2 Reveals a Role for Autophagy in Hereditary Spastic Paraparesis

(2012) Danit Oz-Levi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

(2012) Eisuke Itakura et al.   CELL

A Mammalian Autophagosome Maturation Mechanism Mediated by TECPR1 and the Atg12-Atg5 Conjugate

(2012) Dandan Chen et al.   MOLECULAR CELL

Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy

(2012) Thomas Cullup et al.   NATURE GENETICS

Biogenesis and Cargo Selectivity of Autophagosomes

(2011) Hilla Weidberg et al.   Annual Review of Biochemistry

The role of Tecpr1 in selective autophagy as a cargo receptor

(2011) Michinaga Ogawa et al.   Autophagy

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS