Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

(2020) Kazuyoshi Ishigaki et al.   NATURE GENETICS

The strong propensity of Cadherin‐23 for aggregation inhibits cell migration

(2019) Malay K. Sannigrahi et al.   Molecular Oncology

The Missing Diversity in Human Genetic Studies

(2019) Giorgio Sirugo et al.   CELL

PLD4 is a genetic determinant to systemic lupus erythematosus and involved in murine autoimmune phenotypes

(2019) Shuji Akizuki et al.   ANNALS OF THE RHEUMATIC DISEASES

GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation

(2019) Chikashi Terao et al.   Nature Communications

The pathogenesis of systemic lupus erythematosus: Harnessing big data to understand the molecular basis of lupus

(2019) Michelle D. Catalina et al.   JOURNAL OF AUTOIMMUNITY

Risk Variants with Opposing Functional Effects Result in Hypomorphic Expression of TNIP1 and Other Genes within a 3D Chromatin Network

(2019) Satish Pasula et al.   Arthritis & Rheumatology

Predicting eventual development of lupus nephritis at the time of diagnosis of systemic lupus erythematosus

(2018) Oh Chan Kwon et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

FINEMAP: efficient variable selection using summary data from genome-wide association studies

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Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes

(2016) James P Cook et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A study of the influence of ethnicity on serology and clinical features in lupus

(2016) S A Morais et al.   LUPUS

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

(2016) David L Morris et al.   NATURE GENETICS

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

(2016) Celi Sun et al.   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

The global burden of SLE: prevalence, health disparities and socioeconomic impact

(2016) Erin E. Carter et al.   Nature Reviews Rheumatology

LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation

(2016) Keiko Morimoto et al.   Scientific Reports

Systemic Lupus Erythematosus-associated Neutrophil Cytosolic Factor 2 Mutation Affects the Structure of NADPH Oxidase Complex

(2015) Don L. Armstrong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

(2015) James Bentham et al.   NATURE GENETICS

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus

(2014) Yan Zhang et al.   HUMAN MOLECULAR GENETICS

The Arf6 GTPase-activating Proteins ARAP2 and ACAP1 Define Distinct Endosomal Compartments That Regulate Integrin α5β1 Traffic

(2014) Pei-Wen Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HLA-DRβ1 amino acid positions 11–13–26 explain the majority of SLE–MHC associations

(2014) Kwangwoo Kim et al.   Nature Communications

Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations

(2013) Xana Kim-Howard et al.   HUMAN MOLECULAR GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

The genetics of lupus: a functional perspective

(2012) Sandra G Guerra et al.   ARTHRITIS RESEARCH & THERAPY

A Genome-Wide Association Study Identified AFF1 as a Susceptibility Locus for Systemic Lupus Eyrthematosus in Japanese

(2012) Yukinori Okada et al.   PLoS Genetics

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

(2011) Deborah S. Cunninghame Graham et al.   PLoS Genetics

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus

(2010) Wanling Yang et al.   PLoS Genetics

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

(2009) Vesela Gateva et al.   NATURE GENETICS

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

(2009) Jian-Wen Han et al.   NATURE GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics