Coordination of Zn2+ and Cu2+ to the membrane disrupting fragment of amylin

Neurodegenerative diseases – Understanding their molecular bases and progress in the development of potential treatments

(2015) Magdalena Rowinska-Zyrek et al.   COORDINATION CHEMISTRY REVIEWS

Potentiometric and spectroscopic studies on the copper(ii) complexes of rat amylin fragments. The anchoring ability of specific non-coordinating side chains

(2015) Ágnes Dávid et al.   DALTON TRANSACTIONS

Structural Basis for the Inhibition of Truncated Islet Amyloid Polypeptide Aggregation by Cu(II): Insights into the Bioinorganic Chemistry of Type II Diabetes

(2015) Lina Rivillas-Acevedo et al.   INORGANIC CHEMISTRY

Orientations of Residues along the β-Arch of Self-Assembled Amylin Fibril-Like Structures Lead to Polymorphism

(2014) Vered Wineman-Fisher et al.   BIOMACROMOLECULES

The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme

(2014) Francesco Bellia et al.   JOURNAL OF MASS SPECTROMETRY

The role of copper(ii) in the aggregation of human amylin

(2014) Alessandro Sinopoli et al.   Metallomics

Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide

(2013) Jeffrey R. Brender et al.   CHEMICAL COMMUNICATIONS

Metal ions as modulators of protein conformation and misfolding in neurodegeneration

(2012) Sónia S. Leal et al.   COORDINATION CHEMISTRY REVIEWS

Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)

(2012) Henryk Kozlowski et al.   COORDINATION CHEMISTRY REVIEWS

Association of serum copper levels and glycemic control in patients with type 2 diabetes

(2012) Toyoko Naka et al.   ENDOCRINE JOURNAL

Membrane Disruption and Early Events in the Aggregation of the Diabetes Related Peptide IAPP from a Molecular Perspective

(2011) Jeffrey R. Brender et al.   ACCOUNTS OF CHEMICAL RESEARCH

Pathogenic protein seeding in alzheimer disease and other neurodegenerative disorders

(2011) Mathias Jucker et al.   ANNALS OF NEUROLOGY

Biphasic Effects of Insulin on Islet Amyloid Polypeptide Membrane Disruption

(2011) Jeffrey R. Brender et al.   BIOPHYSICAL JOURNAL

The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation

(2011) Atef Masad et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Two-Site Mechanism for the Inhibition of IAPP Amyloidogenesis by Zinc

(2011) Samer Salamekh et al.   JOURNAL OF MOLECULAR BIOLOGY

The role of metallobiology and amyloid-β peptides in Alzheimer’s disease

(2011) Blaine R. Roberts et al.   JOURNAL OF NEUROCHEMISTRY

Human pro-islet amyloid polypeptide (ProIAPP1–48) forms amyloid fibrils and amyloid spherulites in vitro

(2010) Christopher Exley et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Role of Zinc in Human Islet Amyloid Polypeptide Aggregation

(2010) Jeffrey R. Brender et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of Rat and Human Islet Amyloid Polypeptide IAPP1−19in Micelles by NMR Spectroscopy†

(2008) Ravi Prakash Reddy Nanga et al.   BIOCHEMISTRY

A Single Mutation in the Nonamyloidogenic Region of Islet Amyloid Polypeptide Greatly Reduces Toxicity†

(2008) Jeffrey R. Brender et al.   BIOCHEMISTRY

Mechanism of zinc(II)-promoted amyloid formation: zinc(II) binding facilitates the transition from the partially α-helical conformer to aggregates of amyloid β protein(1–28)

(2008) Christine Talmard et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Copper(II) inhibits the formation of amylin amyloid in vitro

(2007) Benjamin Ward et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy

(2005) Alessandra Gaeta et al.   BRITISH JOURNAL OF PHARMACOLOGY