Multi-trait transcriptome-wide association studies with probabilistic Mendelian randomization

Testing and controlling for horizontal pleiotropy with probabilistic Mendelian randomization in transcriptome-wide association studies

(2020) Zhongshang Yuan et al.   Nature Communications

Multivariate genome-wide analyses of the well-being spectrum

(2019) Bart M. L. Baselmans et al.   NATURE GENETICS

Probabilistic fine-mapping of transcriptome-wide association studies

(2019) Nicholas Mancuso et al.   NATURE GENETICS

A statistical framework for cross-tissue transcriptome-wide association analysis

(2019) Yiming Hu et al.   NATURE GENETICS

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

(2019) Eleonora Porcu et al.   Nature Communications

Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases

(2019) Milic et al.   Biomolecules

TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits

(2019) Sini Nagpal et al.   AMERICAN JOURNAL OF HUMAN GENETICS

OUP accepted manuscript

(2018)   BIOSTATISTICS

Transcriptome-wide association studies accounting for colocalization using Egger regression

(2018) Richard Barfield et al.   GENETIC EPIDEMIOLOGY

Mixed-model association for biobank-scale datasets

(2018) Po-Ru Loh et al.   NATURE GENETICS

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

(2018) Masahiro Kanai et al.   NATURE GENETICS

Multi-trait analysis of genome-wide association summary statistics using MTAG

(2018) Patrick Turley et al.   NATURE GENETICS

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

(2018) Evangelos Evangelou et al.   NATURE GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Methods for meta-analysis of multiple traits using GWAS summary statistics

(2017) Debashree Ray et al.   GENETIC EPIDEMIOLOGY

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the KidneyNovelty and Significance

(2017) Louise V. Wain et al.   HYPERTENSION

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Role of the Immune System in Hypertension

(2017) Bernardo Rodriguez-Iturbe et al.   PHYSIOLOGICAL REVIEWS

Non-parametric genetic prediction of complex traits with latent Dirichlet process regression models

(2017) Ping Zeng et al.   Nature Communications

Evaluating the contribution of genetics and familial shared environment to common disease using the UK Biobank

(2016) María Muñoz et al.   NATURE GENETICS

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

(2016) Georg B Ehret et al.   NATURE GENETICS

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Mark N. Kvale et al.   GENETICS

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Yambazi Banda et al.   GENETICS

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

EPHB4 Protein Expression in Vascular Smooth Muscle Cells Regulates Their Contractility, and EPHB4 Deletion Leads to Hypotension in Mice

(2015) Yujia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immune Mechanisms in Arterial Hypertension

(2015) U. Wenzel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypertension

(2015) Neil R Poulter et al.   LANCET

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Mohammad H Forouzanfar et al.   LANCET

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

A gene-based association method for mapping traits using reference transcriptome data

(2015) Eric R Gamazon et al.   NATURE GENETICS

A review of instrumental variable estimators for Mendelian randomization

(2015) Stephen Burgess et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Cross-Population Joint Analysis of eQTLs: Fine Mapping and Functional Annotation

(2015) Xiaoquan Wen et al.   PLoS Genetics

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Mark N. Kvale et al.   GENETICS

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Yambazi Banda et al.   GENETICS

Statistical Causality from a Decision-Theoretic Perspective

(2015) A. Philip Dawid   Annual Review of Statistics and Its Application

The Immunological Basis of Hypertension

(2014) B. Rodriguez-Iturbe et al.   AMERICAN JOURNAL OF HYPERTENSION

Blood pressure lowering and cardiovascular risk – Authors' reply

(2014) Johan Sundström et al.   LANCET

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

Genes for blood pressure: an opportunity to understand hypertension

(2013) Georg B. Ehret et al.   EUROPEAN HEART JOURNAL

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

A Unified Framework for Association Analysis with Multiple Related Phenotypes

(2013) Matthew Stephens   PLoS One

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

(2013) Xiang Zhou et al.   PLoS Genetics

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

Genome-wide efficient mixed-model analysis for association studies

(2012) Xiang Zhou et al.   NATURE GENETICS

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Single-Tissue and Cross-Tissue Heritability of Gene Expression Via Identity-by-Descent in Related or Unrelated Individuals

(2011) Alkes L. Price et al.   PLoS Genetics

A high-resolution association mapping panel for the dissection of complex traits in mice

(2010) B. J. Bennett et al.   GENOME RESEARCH

Genes determining blood cell traits

(2009) Nancy C Andrews   NATURE GENETICS

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

(2009) Santhi K Ganesh et al.   NATURE GENETICS

Effects of cis and trans Genetic Ancestry on Gene Expression in African Americans

(2008) Alkes L. Price et al.   PLoS Genetics