Design, synthesis and biological evaluation of novel benzodioxole derivatives as COX inhibitors and cytotoxic agents

Ortho versus Meta Chlorophenyl-2,3-Benzodiazepine Analogues: Synthesis, Molecular Modeling, and Biological Activity as AMPAR Antagonists

(2020) Mohammad Qneibi et al.   ACS Omega

Synthesis, Biological Activity, and Molecular Modeling Studies of Pyrazole and Triazole Derivatives as Selective COX-2 Inhibitors

(2020) Mohyeddin Assali et al.   Journal of Chemistry

The inhibitory role of curcumin derivatives on AMPA receptor subunits and their effect on the gating biophysical properties

(2019) Mohammad Qneibi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Carlina curetum plant phytoconstituents, enzymes inhibitory and cytotoxic activity on cervical epithelial carcinoma and colon cancer cell lines

(2019) Nidal Amin Jaradat et al.   European Journal of Integrative Medicine

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

(2018) J. Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics

(2017) Mohammed M.A. Hawash et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity

(2015) Bing Liu et al.   Cancer Cell International

Novel 3,4-methylenedioxybenzene scaffold incorporated 1,3,5-trisubstituted-2-pyrazolines: Synthesis, characterization and evaluation for chemotherapeutic activity

(2015) SR Deshpande et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

3-Methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents

(2015) Khaled R. A. Abdellatif et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors

(2014) Guanghai Jin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, docking simulation, biological evaluations and 3D-QSAR study of 5-Aryl-6-(4-methylsulfonyl)-3-(metylthio)-1,2,4-triazine as selective cyclooxygenase-2 inhibitors

(2013) Hamid Irannejad et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system

(2012) N. S. Kirkby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis

(2011) William L. Smith et al.   CHEMICAL REVIEWS

Photosynthesis of dimeric cinnamaldehyde, eugenol, and safrole as antimicrobial agents

(2011) Suzan A. Khayyat   Journal of Saudi Chemical Society

Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents

(2010) Ameen Abu-Hashem et al.   ACTA PHARMACEUTICA

Emotion Recollected in Tranquility: Lessons Learned from the COX-2 Saga

(2010) Tilo Grosser et al.   Annual Review of Medicine

Synthesis of novel 3,5-diaryl pyrazole derivatives using combinatorial chemistry as inhibitors of tyrosinase as well as potent anticancer, anti-inflammatory agents

(2010) Babasaheb P. Bandgar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of ketoprofen analogs as potent cyclooxygenase-2 inhibitors

(2010) Afshin Zarghi et al.   BIOORGANIC & MEDICINAL CHEMISTRY