OMIP-037: 16-color panel to measure inhibitory receptor signatures from multiple human immune cell subsets

T-Cell Immunoglobulin and ITIM Domain (TIGIT) Associates with CD8+ T-Cell Exhaustion and Poor Clinical Outcome in AML Patients

(2016) Y. Kong et al.   CLINICAL CANCER RESEARCH

OMIP-031: Immunologic checkpoint expression on murine effector and memory T-cell subsets

(2016) Satoshi Nemoto et al.   CYTOMETRY PART A

Pointed Progress in Second-Line Advanced Non–Small-Cell Lung Cancer: The Rapidly Evolving Field of Checkpoint Inhibition

(2016) Barbara Melosky et al.   JOURNAL OF CLINICAL ONCOLOGY

TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection

(2016) Glen M. Chew et al.   PLoS Pathogens

The Upregulation of LAG-3 on T Cells Defines a Subpopulation with Functional Exhaustion and Correlates with Disease Progression in HIV-Infected Subjects

(2015) Xiaoling Tian et al.   JOURNAL OF IMMUNOLOGY

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer

(2015) Julie Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma

(2015) Stephen M. Ansell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

(2015) Robert J. Motzer et al.   NEW ENGLAND JOURNAL OF MEDICINE

NK cell exhaustion: bad news for chronic disease?

(2015) Jamie L. Schafer et al.   Oncotarget

Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators

(2015) Isabelle Le Mercier et al.   Frontiers in Immunology

Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab

(2015) Roberto Salgado et al.   JAMA Oncology

The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function

(2014) Robert J. Johnston et al.   CANCER CELL

Molecular and Transcriptional Basis of CD4+ T Cell Dysfunction during Chronic Infection

(2014) Alison Crawford et al.   IMMUNITY

Coinhibitory receptors and CD8 T cell exhaustion in chronic infections

(2014) Vijay K. Kuchroo et al.   Current Opinion in HIV and AIDS

CD160-Associated CD8 T-Cell Functional Impairment Is Independent of PD-1 Expression

(2014) Selena Viganò et al.   PLoS Pathogens

Invariant natural killer T (iNKT) cell exhaustion in sarcoidosis

(2013) Jennifer E. Snyder-Cappione et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Follicular Lymphoma Cells Induce Changes in T-Cell Gene Expression and Function: Potential Impact on Survival and Risk of Transformation

(2013) Shahryar Kiaii et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nivolumab plus Ipilimumab in Advanced Melanoma

(2013) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity

(2012) L. C. Ndhlovu et al.   BLOOD

Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

(2011) S.-R. Woo et al.   CANCER RESEARCH

Vstm3 is a member of the CD28 family and an important modulator of T-cell function

(2011) Steven D. Levin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD160: A unique activating NK cell receptor

(2011) Philippe Le Bouteiller et al.   IMMUNOLOGY LETTERS

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Clinical impact of tumor-infiltrating lymphocytes for survival in stage II colon cancer

(2010) Won-Suk Lee et al.   CANCER

Expression and function of PD-1 in human γδ T cells that recognize phosphoantigens

(2010) Masashi Iwasaki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Proliferation Capacity and Cytotoxic Activity Are Mediated by Functionally and Phenotypically Distinct Virus-Specific CD8 T Cells Defined by Interleukin-7R  (CD127) and Perforin Expression

(2010) C. Cellerai et al.   JOURNAL OF VIROLOGY

Galectin-9/TIM-3 Interaction Regulates Virus-Specific Primary and Memory CD8+ T Cell Response

(2010) Sharvan Sehrawat et al.   PLoS Pathogens

CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator

(2008) Guifang Cai et al.   NATURE IMMUNOLOGY