Article
Agricultural Engineering
Sian Liu, Zhaolong Meng, Hanyue Zhang, Yixuan Chu, Yuyu Qiu, Biao Jin, Li Wang
Summary: This study identified and characterized 13 gene families involved in flavonoid biosynthesis in Ginkgo biloba, revealing some unique features not found in angiosperms. The results provide a basis for further investigation of the genes regulating G. biloba flavonoid biosynthesis.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Forestry
Wanwen Yu, Jinfeng Cai, Huimin Liu, Zhiguo Lu, Jingjing Hu, Yan Lu
Summary: This study investigates the transcriptomic regulation mechanisms of Ginkgo biloba leaves in response to dehydration and rehydration, revealing key genes involved in abscisic acid biosynthesis, ROS elimination, and flavonoid/bilobalide biosynthesis. Genes related to water transport and cell wall enlargement were differentially expressed under water stress, but showed reversal under rehydration conditions. Coexpression networks of genes were established, identifying hub genes that play crucial roles in the response to water stress and rewatering.
Article
Forestry
Xiaoming Yang, Qi Xu, Linlin Le, Tingting Zhou, Wanwen Yu, Guibin Wang, Fang-Fang Fu, Fuliang Cao
Summary: Gingko biloba callus undergoes browning, which reduces its regenerative capacity and usefulness. This study identified the cellular and biochemical changes that accompany browning in callus cells derived from immature ginkgo embryos. It was found that browning calli had a loosely arranged cell structure and accumulated more tannins. The activation of phenylpropanoid metabolism and the upregulation of genes involved in flavonoid biosynthesis were also observed in browning calli.
JOURNAL OF FORESTRY RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Yating Tian, Xin Han, Yanshu Qu, Yifan Zhang, Hao Rong, Kai Wu, Li'an Xu
Summary: This study systematically investigated the LBD gene family in ginkgo, including gene structure, phylogenetic analysis, and expression profiling. The results revealed two distinct classes of LBD genes, with the class II genes showing enriched expression in different tissues and developmental stages and playing a key role in abiotic stress treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Xin-Guang Liu, Xu Lu, Wen Gao, Ping Li, Hua Yang
Summary: Ginkgo biloba is a unique plant with compounds that broaden the chemical diversity of herbal medicine, used for cardiovascular disease prevention and treatment. However, traditional extraction methods yield low purity and content of active compounds, highlighting the need for new strategies to meet international market demand.
NATURAL PRODUCT REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Yaping Hu, Yun Zhang, Petr Smarda, Petr Bures, Qirong Guo
Summary: Having different number of genome copies affects transcription and metabolite production in plants. This study investigated the effect of haploidy on flavonoid content in ginkgos by measuring the flavonoid content in leaves of haploid and diploid grafted plants and analyzing their transcriptomes and proteomes. Haploids had smaller leaves and lower flavonoid content compared to diploids. The downregulation of key genes involved in flavonoid biosynthesis regulation may contribute to the lower flavonoid content in haploids.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Plant Sciences
Wanwen Yu, Huimin Liu, Jiaqin Luo, Shuqing Zhang, Peng Xiang, Wei Wang, Jinfeng Cai, Zhiguo Lu, Zhidong Zhou, Jingjing Hu, Yan Lu
Summary: The study revealed that partial root-zone drying led to greater flavonoid accumulation compared to full root-zone drying in ginkgo leaves. Metabolites, structural genes, and transcription factors played crucial roles in regulating flavonoid concentrations in response to drought stress. This highlights the efficiency of partial root-zone drying in harvesting ginkgo leaves with high flavonoid concentrations.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2022)
Article
Plant Sciences
Zhaogeng Lu, Likui Zhu, Jinkai Lu, Nan Shen, Lu Wang, Sian Liu, Qingjie Wang, Wanwen Yu, Hisashi Kato-Noguchi, Weixing Li, Biao Jin, Li Wang, Jinxing Lin
Summary: Trunk truncation can stimulate tree rejuvenation and increase the biomass and flavonoid content of Ginkgo biloba leaves.
HORTICULTURE RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Qingjie Wang, Shiyuan Xu, Lei Zhong, Xiya Zhao, Li Wang
Summary: This study investigates the effects of different concentrations of ZnO-NPs on the growth and accumulation of flavonoids in Ginkgo biloba. The results show that 25 mg/L of ZnO-NPs enhances plant growth and flavonoid content, while higher concentrations have an inhibitory effect. The promotion of flavonoid accumulation is mainly attributed to the upregulation of flavonol structural genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Huan Han, Liwei Dong, Weiwei Zhang, Yongling Liao, Lina Wang, Qijian Wang, Jiabao Ye, Feng Xu
Summary: Ginkgo biloba, an economic plant resource from China, is the oldest relict plant on Earth. Flavonoids extracted from G. biloba have been shown to have beneficial effects on cardiovascular and cerebrovascular diseases. In this study, the GbbZIP08 gene was isolated and characterized, and its overexpression in tobacco led to increased flavonoid accumulation and upregulation of flavonoid-synthesis-related genes.
JOURNAL OF PLANT PHYSIOLOGY
(2023)
Article
Agricultural Engineering
Bing He, Hailin Liu, Xin Han, Peng Cui, Li-an Xu
Summary: This study successfully identified 780 metabolites from G. biloba mature leaves by combining transcriptome and metabolome data, providing the most detailed summary of metabolites in G. biloba leaves to date. Additionally, a co-regulation mechanism of flavonoid and stilbene synthesis was preliminarily found, filling in some gaps in the G. biloba metabolome landscape.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Plant Sciences
Hailin Liu, Xiaobo Wang, Guibin Wang, Peng Cui, Shigang Wu, Cheng Ai, Nan Hu, Alun Li, Bing He, Xiujuan Shao, Zhichao Wu, Hu Feng, Yuxiao Chang, Desheng Mu, Jing Hou, Xiaogang Dai, Tongming Yin, Jue Ruan, Fuliang Cao
Summary: Analysis of a nearly complete genome of Ginkgo biloba has revealed the reasons behind genome expansion and identified candidate genes associated with the formation of spermatophore flagellum, advancing our understanding of gymnosperm evolution. The genome provides new insights into the expansion and evolution of gymnosperms, along with a detailed annotation of protein-coding genes.
Article
Plant Sciences
Y. Li, H. Han, M. Fu, X. Zhou, J. Ye, F. Xu, W. Zhang, Y. Liao, X. Yang
Summary: This study analyzed the characteristics and expression patterns of the NAC transcription factor family in Ginkgo biloba using bioinformatics and quantitative reverse transcription PCR. The results showed that NAC transcription factors play important roles in plant growth and development, as well as in response to abiotic stresses and flavonoid biosynthesis in Ginkgo biloba.
Article
Plant Sciences
Pengyan Zhou, Zesen Wang, Yingang Li, Qi Zhou
Summary: MADS-box transcription factors play important roles in various organisms, including the development of flower organ structures and seed development in plants. This study identified and analyzed MADS-box genes in two genome versions of Ginkgo biloba, revealing the presence of specific gene subfamilies and variations in gene structure. The expression analysis demonstrated the involvement of these genes in the development of Ginkgo reproductive organs, suggesting a potential genetic role in sexual differentiation.
Article
Biochemistry & Molecular Biology
Ying Guo, Tongli Wang, Fang-Fang Fu, Yousry A. El-Kassaby, Guibin Wang
Summary: The study revealed variations in photosynthetic capacity and related compounds in developing ginkgo leaves. A co-expression network was constructed to demonstrate the regulatory role of transcription factors in the photosynthetic light reaction pathway. This analysis identified candidate genes that could potentially improve photosynthetic capacity and yield in ginkgo trees.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)