期刊
PATHOGENS
卷 9, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/pathogens9090729
关键词
foot-and-mouth disease virus; immune escape; innate immune response; interferon; protein interaction; viral protein
类别
资金
- National Natural Science Foundation of China [31972684]
- National Key R&D Program of China [2018YFD0502100]
Foot-and-mouth disease virus (FMDV) causes a highly contagious vesicular disease in cloven-hoofed livestock that results in severe consequences for international trade, posing a great economic threat to agriculture. The FMDV infection antagonizes the host immune responses via different signaling pathways to achieve immune escape. Strategies to escape the cell immune system are key to effective infection and pathogenesis. This review is focused on summarizing the recent advances to understand how the proteins encoded by FMDV antagonize the host innate and adaptive immune responses.
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