Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8+ T cells

Remodeling of light and dark zone follicular dendritic cells governs germinal center responses

(2020) Natalia B. Pikor et al.   NATURE IMMUNOLOGY

Complexities of Type I Interferon Biology: Lessons from LCMV

(2019) Tamara Suprunenko et al.   Viruses-Basel

CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer

(2019) Laura M. McLane et al.   Annual Review of Immunology

Lymphatic Endothelial Cells Are Essential Components of the Subcapsular Sinus Macrophage Niche

(2019) Isabelle Mondor et al.   IMMUNITY

Fibroblastic reticular cells at the nexus of innate and adaptive immune responses

(2019) Christian Perez‐Shibayama et al.   IMMUNOLOGICAL REVIEWS

IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival

(2019) Saikat Majumder et al.   NATURE IMMUNOLOGY

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche

(2019) Abdouramane Camara et al.   IMMUNITY

Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

(2019) Karin Schaeuble et al.   PLOS BIOLOGY

Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling

(2019) Flavian D. Brown et al.   NATURE IMMUNOLOGY

Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity

(2018) Lauren B. Rodda et al.   IMMUNITY

Stromal cell networks coordinate immune response generation and maintenance

(2018) Yannick O. Alexandre et al.   IMMUNOLOGICAL REVIEWS

Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis

(2018) Hsin-Ying Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A short field guide to fibroblast function in immunity

(2018) Matthew B. Buechler et al.   SEMINARS IN IMMUNOLOGY

Antiviral interferon response at single-cell resolution

(2018) Soheil Rastgou Talemi et al.   IMMUNOLOGICAL REVIEWS

The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation

(2018) Konstantin Knoblich et al.   PLOS BIOLOGY

A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node

(2018) Arata Takeuchi et al.   Frontiers in Immunology

IRF9 Prevents CD8 + T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection

(2017) Magdalena Huber et al.   JOURNAL OF VIROLOGY

Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis

(2017) Lalit Kumar Dubey et al.   Nature Communications

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis

(2017) Miao Yu et al.   Scientific Reports

The GenePattern Notebook Environment

(2017) Michael Reich et al.   Cell Systems

Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs

(2016) Cristina Gil-Cruz et al.   NATURE IMMUNOLOGY

Diffusion maps for high-dimensional single-cell analysis of differentiation data

(2015) Laleh Haghverdi et al.   BIOINFORMATICS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Phenotypic and Morphological Properties of Germinal Center Dark ZoneCxcl12-Expressing Reticular Cells

(2015) Lauren B. Rodda et al.   JOURNAL OF IMMUNOLOGY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection

(2015) M. Gaya et al.   SCIENCE

Fate mapping reveals origin and dynamics of lymph node follicular dendritic cells

(2014) Meryem Jarjour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Organizer-Like Reticular Stromal Cell Layer Common to Adult Secondary Lymphoid Organs

(2014) T. Katakai et al.   JOURNAL OF IMMUNOLOGY

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells

(2014) Viviana Cremasco et al.   NATURE IMMUNOLOGY

Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity

(2013) Qian Chai et al.   IMMUNITY

Chronic but Not Acute Virus Infection Induces Sustained Expansion of Myeloid Suppressor Cell Numbers that Inhibit Viral-Specific T Cell Immunity

(2013) Brian A. Norris et al.   IMMUNITY

Identification of a New Stromal Cell Type Involved in the Regulation of Inflamed B Cell Follicles

(2013) Cyrille Mionnet et al.   PLOS BIOLOGY

Antigen amount dictates CD8+T-cell exhaustion during chronic viral infection irrespective of the type of antigen presenting cell

(2012) Kirsten Richter et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks

(2012) Deepali Malhotra et al.   NATURE IMMUNOLOGY

Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection

(2012) M. A. Paley et al.   SCIENCE

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers

(2011) Xiaoming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells

(2011) GuoQiang Sun et al.   Nature Communications

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells

(2010) Clémentine Schilte et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression

(2010) A. Bergthaler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation

(2009) Tri Giang Phan et al.   NATURE IMMUNOLOGY

High antigen levels are the cause of T cell exhaustion during chronic viral infection

(2009) S. N. Mueller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone

(2008) Elke Scandella et al.   NATURE IMMUNOLOGY