Amyloidosis increase is not attenuated by long-term calorie restriction or related to neuron density in the prefrontal cortex of extremely aged rhesus macaques

Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease

(2019) Michael F. Egan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Brains of rhesus monkeys display Aβ deposits and glial pathology while lacking Aβ dimers and other Alzheimer's pathologies

(2019) Jing Zhang et al.   AGING CELL

Hat die Alzheimer-Forschung versagt?

(2019) Christian Haass et al.   NERVENARZT

2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial

(2019) William E Kraus et al.   Lancet Diabetes & Endocrinology

Neuroanatomical Abnormalities in Older Depressed Adults With Apathy: A Systematic Review

(2019) Monique A. Pimontel et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction

(2019) Aritra Bhattacherjee et al.   Nature Communications

Oligomeric Aβ in the monkey brain impacts synaptic integrity and induces accelerated cortical aging

(2019) Danielle Beckman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology

(2018) Constantinos D. Paspalas et al.   Alzheimers & Dementia

A Study of Amyloid-β and Phosphotau in Plaques and Neurons in the Hippocampus of Alzheimer’s Disease Patients

(2018) Diana Furcila et al.   JOURNAL OF ALZHEIMERS DISEASE

Calorie restriction protects against apoptosis, mitochondrial oxidative stress and increased calcium signaling through inhibition of TRPV1 channel in the hippocampus and dorsal root ganglion of rats

(2018) Fatih Gültekin et al.   METABOLIC BRAIN DISEASE

Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation

(2018) Niran Hadad et al.   NEUROBIOLOGY OF AGING

ABBY

(2018) Jeffrey L. Cummings et al.   NEUROLOGY

Intracellular amyloid beta expression leads to dysregulation of the mitogen-activated protein kinase and bone morphogenetic protein-2 signaling axis

(2018) Eric Cruz et al.   PLoS One

Does Calorie Restriction in Primates Increase Lifespan? Revisiting Studies on Macaques (Macaca mulatta ) and Mouse Lemurs (Microcebus murinus )

(2018) Eric Le Bourg   BIOESSAYS

Racial and ethnic estimates of Alzheimer's disease and related dementias in the United States (2015–2060) in adults aged ≥65 years

(2018) Kevin A. Matthews et al.   Alzheimers & Dementia

An overview of nonhuman primates in aging research

(2017) Julie A. Mattison et al.   EXPERIMENTAL GERONTOLOGY

Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry

(2017) Larissa I. Estrada et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Comparing the Aggregation Free Energy Landscapes of Amyloid Beta(1–42) and Amyloid Beta(1–40)

(2017) Weihua Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Caloric restriction improves health and survival of rhesus monkeys

(2017) Julie A. Mattison et al.   Nature Communications

A phase III randomized trial of gantenerumab in prodromal Alzheimer’s disease

(2017) Susanne Ostrowitzki et al.   Alzheimers Research & Therapy

Direct and indirect cost of managing alzheimer’s disease and related dementias in the United States

(2017) Arijita Deb et al.   Expert Review of Pharmacoeconomics & Outcomes Research

Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia

(2017) Devin Wahl et al.   Clinical Interventions in Aging

Non-human primates as a model for aging

(2017) Ricki J. Colman   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Patterns of Cortical and Subcortical Amyloid Burden across Stages of Preclinical Alzheimer’s Disease

(2016) Emily C. Edmonds et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Effect of Calorie Restriction on Mood, Quality of Life, Sleep, and Sexual Function in Healthy Nonobese Adults

(2016) Corby K. Martin et al.   JAMA Internal Medicine

Calorie Restriction Improves Cognitive Decline via Up-Regulation of Brain-Derived Neurotrophic Factor

(2015) Takuya Kishi et al.   International Heart Journal

Confocal Imaging–Guided Laser Ablation of Basal Cell Carcinomas: An Ex Vivo Study

(2015) Heidy Sierra et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Novel Insights into NeuN: from Neuronal Marker to Splicing Regulator

(2015) Wei Duan et al.   MOLECULAR NEUROBIOLOGY

Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice

(2015) Marissa J. Schafer et al.   NEUROBIOLOGY OF AGING

Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates

(2014) Leticia Forny-Germano et al.   JOURNAL OF NEUROSCIENCE

Coordinated Gene Expression of Neuroinflammatory and Cell Signaling Markers in Dorsolateral Prefrontal Cortex during Human Brain Development and Aging

(2014) Christopher T. Primiani et al.   PLoS One

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

Interleukin-8 and interleukin-10, brain volume and microstructure, and the influence of calorie restriction in old rhesus macaques

(2013) A. A. Willette et al.   AGE

Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model

(2013) Edoardo Parrella et al.   AGING CELL

Normal Cognitive Aging

(2013) Caroline N. Harada et al.   CLINICS IN GERIATRIC MEDICINE

Monetary Costs of Dementia in the United States

(2013) Michael D. Hurd et al.   NEW ENGLAND JOURNAL OF MEDICINE

Accelerated aging-related transcriptome changes in the female prefrontal cortex

(2012) Yuan Yuan et al.   AGING CELL

Safety and biomarker effects of solanezumab in patients with Alzheimer’s disease

(2012) Martin Farlow et al.   Alzheimers & Dementia

A stereological study of the numbers of neurons and glia in the primary visual cortex across the lifespan of male and female rhesus monkeys

(2012) Eustathia Lela Giannaris et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A Calorie-Restricted Diet Decreases Brain Iron Accumulation and Preserves Motor Performance in Old Rhesus Monkeys

(2012) E. K. Kastman et al.   JOURNAL OF NEUROSCIENCE

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

(2012) Julie A. Mattison et al.   NATURE

Increased working memory-related brain activity in middle-aged women with cognitive complaints

(2012) Julie A. Dumas et al.   NEUROBIOLOGY OF AGING

Neuron numbers in the hypothalamus of the normal aging rhesus monkey: Stability across the adult lifespan and between the sexes

(2011) D.E. Roberts et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A review of the structural alterations in the cerebral hemispheres of the aging rhesus monkey

(2011) Alan Peters et al.   NEUROBIOLOGY OF AGING

Volumetric Correlates of Spatiotemporal Working and Recognition Memory Impairment in Aged Rhesus Monkeys

(2010) J. L. Shamy et al.   CEREBRAL CORTEX

Classification and basic pathology of Alzheimer disease

(2009) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Effects of normal aging on prefrontal area 46 in the rhesus monkey

(2009) Jennifer Luebke et al.   BRAIN RESEARCH REVIEWS

Identification of Neuronal Nuclei (NeuN) as Fox-3, a New Member of the Fox-1 Gene Family of Splicing Factors

(2009) Kee K. Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease

(2008) Milos D. Ikonomovic et al.   BRAIN

Preservation of Neuronal Number Despite Age-Related Cortical Brain Atrophy in Elderly Subjects Without Alzheimer Disease

(2008) Stefanie H. Freeman et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY