4.4 Review

The Chemistry and Bio-Medicinal Significance of Pyrimidines & Condensed Pyrimidines

期刊

CURRENT TOPICS IN MEDICINAL CHEMISTRY
卷 16, 期 28, 页码 3133-3174

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1568026616666160609100410

关键词

Bioactive Heterocycles; Pyrimidines; Condensed Pyrimidines; Biological significance; Medicinal significance; Synthesis

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This review discusses the biological and medicinal significance of one of the most important and interesting heterocyclic ring systems, the pyrimidine and its condensed derivatives. Herein, various physiologically important molecules, as well as, therapeutically used drugs having a pyrimidine or condensed pyrimidine system in their chemical structures, have been covered. The chemistry and synthesis of pyrimidines have also been briefly discussed.

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