Article
Environmental Sciences
Ana M. O. Azevedo, Andre G. Vilaranda, Ana F. D. C. Neves, Maria Joao Sousa, Joao L. M. Santos, M. Lucia M. F. S. Saraiva
Summary: Saccharomyces cerevisiae was used as a eukaryotic model organism to study the toxic effects of various compounds in an automated spectrophotometric method. The results showed that GUMBOS exhibited higher toxicity to yeast cells and could be promising antimicrobial candidates, while DESs were less toxic than ILs. The automated methodology demonstrated satisfactory repeatability and reproducibility, aligning with Green Chemistry principles.
Article
Chemistry, Multidisciplinary
Yui Kato, Takuya Uto, Daisuke Tanaka, Kojiro Ishibashi, Akiko Kobayashi, Masaharu Hazawa, Richard W. Wong, Kazuaki Ninomiya, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda
Summary: Cell cryopreservation is essential for long-term storage, but some cell lines cannot be efficiently cryopreserved. Research shows that a synthetic zwitterion solution can achieve good cryopreservation, but not with high efficiency for certain cells. Further study on the cryoprotective effects and mechanisms of zwitterions is needed for optimization and better results.
COMMUNICATIONS CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Yui Kato, Yuya Matsuda, Takuya Uto, Daisuke Tanaka, Kojiro Ishibashi, Takeru Ishizaki, Akio Ohta, Akiko Kobayashi, Masaharu Hazawa, Richard W. Wong, Kazuaki Ninomiya, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda
Summary: During long-term cell storage, the addition of cryoprotectants to inhibit ice crystal formation is necessary. However, the high osmotic pressure and dehydration caused by non-cell-permeable cryoprotectants often damage cells. In this study, researchers developed a poly(zwitterion) isotonic cryoprotectant that forms a firm matrix around cells, preventing the influx of ice crystal nuclei without the need for high osmotic pressure and dehydration.
COMMUNICATIONS CHEMISTRY
(2023)
Review
Crystallography
Andromachi Tzani, Maria-Anna Karadendrou, Styliani Kalafateli, Vasiliki Kakokefalou, Anastasia Detsi
Summary: This review presents the latest scientific research on the synthesis, characterization, and applications of Biocompatible Ionic Liquids (Bio-ILs). Bio-ILs are a new class of ILs derived or synthesized from natural compounds, combined with the biocompatibility of molecules, and have tailor-made physicochemical properties, making them suitable for various scientific fields.
Article
Chemistry, Multidisciplinary
Malgorzata Musia, Edward Zorebski, Katarzyna Malarz, Michal Kuczak, Anna Mrozek-Wilczkiewicz, Johan Jacquemin, Marzena Dzida
Summary: The study revealed that imidazolium-based ILs combined with dialkyl phosphate anions or with the ethyl sulfate anion are the least cytotoxic. Some ILs can potentially be used as hydraulic fluids or efficient solvents, while others have potential as heat transfer media and base fluids.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Chemistry, Physical
Alex Spiess, Philipp Brandt, Alexa Schmitz, Christoph Janiak
Summary: Water sorption characteristics of six pure hydrophilic ionic liquids were investigated, revealing a steady and high water uptake with a small hysteresis between absorption and desorption. These findings provide valuable insights into the water sorption behavior of ionic liquids.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Multidisciplinary
Tetsuya Hirata, Takahiro Takekiyo, Yukihiro Yoshimura, Yuko Tokoro, Takeru Ishizaki, Yasuhiko Kizuka, Kosuke Kuroda
Summary: In this report, biocompatible materials for cryostorage of unstable proteins, such as cancer-related enzyme GnT-V, were studied. It was found that synthetic zwitterion solutions better retained the activity of GnT-V and the amount of protein after freezing compared to glycerol solution. This study highlights the potential utility of synthetic zwitterions as novel cryoprotectants.
Review
Biochemistry & Molecular Biology
Ana R. P. Goncalves, Xavier Paredes, A. F. Cristino, F. J. V. Santos, Carla S. G. P. Queiros
Summary: Ionic liquids were initially touted as environmentally friendly replacements for traditional solvents, but research on their interactions with organisms is lacking. Lipophilicity and the type of cation play key roles in toxicity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Physical
Madhur Babu Singh, Pallavi Jain, Preeti Chaudhary, Indra Bahadur, Kashmiri Lal, Vinod Kumar, Prashant Singh, Himani, Anirudh Pratap Singh Raman
Summary: Ionic liquids (ILs) have a wide range of features, uses, and environmentally friendly nature, making them potential substitutes for organic solvents in addressing pollution. ILs possess unique thermal, physical, chemical, and biological properties, which can be modified by altering their cationic and anionic parts. Their applications in protein stabilization, organic transformation, nanomaterials, etc., indicate their significant impact on research and development.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Engineering, Biomedical
Kevin Peng, Yongsheng Gao, Pavimol Angsantikul, Anthony LaBarbiera, Morgan Goetz, Alexander M. Curreri, Danika Rodrigues, Eden E. L. Tanner, Samir Mitragotri
Summary: Studies have shown that choline-based ionic liquids can significantly enhance the absorption of macromolecular drugs in the gastrointestinal tract by reducing drug interactions with mucus or disrupting the mucus layer, potentially improving the success rate of oral drug delivery.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Polymer Science
Nihal Yasir, Amir Sada Khan, Muhammad Faheem Hassan, Taleb H. Ibrahim, Mustafa I. Khamis, Paul Nancarrow
Summary: In this study, agar-alginate beads impregnated with [P-66614][Br] ionic liquid were synthesized and characterized for wastewater treatment containing low concentrations of phenolic compounds. The adsorbent showed enhanced thermal stability and porous surface. Optimum conditions for phenol removal were determined, and the adsorption process followed pseudo-second order kinetics and fitted the Freundlich isotherm model. The adsorbent could be regenerated and reused for at least four cycles without significant loss in adsorption efficiency.
Article
Chemistry, Multidisciplinary
Marika Turek, Robert Biczak, Barbara Pawlowska, Ewa Rozycka-Sokolowska, Krzysztof Owsianik, Bernard Marciniak, Piotr Balczewski
Summary: The use of optically active forms of commercial chiral herbicides may be more effective and environmentally safer. This study synthesized a series of chiral quaternary ammonium salts and investigated their selective toxicity towards aquatic bacteria and terrestrial plants. The results showed that these salts exhibited enantioselective toxicity towards all tested organisms.
Article
Chemistry, Physical
Oscar Cabeza, Luisa Segade, Montserrat Dominguez-Perez, Esther Rilo, David Ausin, Julio A. Seijas, M. Pilar Vazquez-Tato, Vladimir Matleev, Alexandr Ievlev, Josefa Salgado, Luis M. Varela
Summary: This paper presents a study on a new family of ionic liquids, investigating the differences in electrical conductivity, viscosity, and diffusion coefficient among various metal thiocyanate ILs. Despite their chemical similarities, these compounds exhibit significant variations in transport properties.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Genetics & Heredity
Sutton E. Wheelis, Claudia C. Biguetti, Shruti Natarajan, Bhuvana Lakkasetter Chandrashekar, Alexandra Arteaga, Jihad El Allami, Gustavo P. Garlet, Danieli C. Rodrigues
Summary: This study evaluated the effects of IonL-Phe on early healing and osseointegration of titanium dental implants in different rat demographics. The results showed that IonL-coated samples had increased bone-to-implant contact across all demographic groups. IonL-Phe coating presented the potential to prevent failures in scenarios challenged by bacteria.
Article
Green & Sustainable Science & Technology
Sergio S. de Jesus, Rubens Maciel Filho
Summary: Ionic liquids are molten salts with excellent chemical and thermal stability, which have the potential to replace traditional organic solvents. However, their synthesis, toxicity, and biodegradability pose challenges to their environmentally friendly use. Analyzing the processes of synthesis, recovery and recycling, toxicity, and biodegradability reveals the need for further improvements in ionic liquid design to meet the principles of green chemistry.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2022)
Article
Chemistry, Physical
Fatima C. Teixeira, Ana de Sa, Antonio P. S. Teixeira, V. M. Ortiz-Martinez, A. Ortiz, I Ortiz, C. M. Rangel
Summary: The study focused on the development of new Nafion membranes by incorporating aryl- or azaheteroaromatic bisphosphonate compounds as dopants, resulting in enhanced proton conductivity properties compared to commercial Nafion membranes. These doped membranes showed improved performance in fuel cells at different temperatures, with a maximum power output of around 383 mW cm(-2) at 70 degrees C. The membranes also demonstrated potential advantages in restricting gas crossover, as indicated by higher open circuit potentials compared to Nafion membranes under the same conditions.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Energy & Fuels
Pedro Andreo-Martinez, Victor Manuel Ortiz-Martinez, Nuria Garcia-Martinez, Francisco Jose Hernandez-Fernandez, Antonia Perez de los Rios, Joaquin Quesada-Medina
Summary: The elucidation of lignin structural features is crucial for its efficient application as a source of phenolic compounds. A new fractionation method was developed to selectively separate lignin from saccharides in organosolv extracts, allowing for a better understanding of their composition and structure. The application of analytical methods like GPC, thioacidolysis, and GC-MS provided valuable information on the purity and degradation state of lignin and hemicelluloses in the extracts.
BIOMASS CONVERSION AND BIOREFINERY
(2021)
Article
Engineering, Chemical
V. M. Ortiz-Martinez, L. Gomez-Coma, C. Tristan, G. Perez, M. Fallanza, A. Ortiz, R. Ibanez, I Ortiz
Article
Engineering, Multidisciplinary
Victor M. Ortiz-Martinez, Jesus Martinez-Frutos, Eloy Hontoria, Francisco J. Hernandez-Fernandez, Jose A. Egea
Summary: Wastewater treatment process design involves optimizing multiple conflicting objectives, and detecting different equivalent solutions is crucial for designers in efficiently switching to new optimal operation policies. This study focuses on the dynamic multi-objective optimization of a municipal wastewater treatment plant model, optimizing an economic cost term and an effluent quality index simultaneously. Simulating different realistic scenarios reveals that multiple solutions exist at least in some areas of the Pareto front.
OPTIMIZATION AND ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Iwona Gajda, Oluwatosin Obata, Maria Jose Salar-Garcia, John Greenman, Ioannis A. Ieropoulos
BIOELECTROCHEMISTRY
(2020)
Review
Environmental Sciences
Pedro Andreo-Martinez, Victor Manuel Ortiz-Martinez, Nuria Garcia-Martinez, Pablo Pagan Lopez, Joaquin Quesada-Medina, Miguel Angel Camara, Jose Oliva
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2020)
Article
Electrochemistry
M. J. Salar-Garcia, X. A. Walter, J. Gurauskis, A. de Ramon Fernandez, I. Ieropoulos
Summary: By adjusting the iron oxide content and sintering temperature, performance of ceramic membranes was enhanced in this study, improving the power performance of MFCs and increasing power output. The system operated stably for 65 days, demonstrating long-term functionality of the various materials assessed.
ELECTROCHIMICA ACTA
(2021)
Article
Thermodynamics
A. de Ramon-Fernandez, M. J. Salar-Garcia, D. Ruiz Fernandez, J. Greenman, I. A. Ieropoulos
Article
Computer Science, Interdisciplinary Applications
Pedro Andreo-Martinez, Victor Manuel Ortiz-Martinez, Andres Munoz, Pablo Menchon-Sanchez, Joaquin Quesada-Medina
Summary: Constructed wetlands are recognized as efficient and sustainable engineering systems for wastewater treatment. The study of their components in different phases is crucial for achieving an environmentally-friendly approach. So far, there are no complete tools available to measure both direct and indirect greenhouse gas emissions in constructed wetlands.
ENVIRONMENTAL MODELLING & SOFTWARE
(2021)
Article
Engineering, Chemical
V. M. Ortiz-Martinez, L. Gomez-Coma, G. Perez, A. Ortiz, I Ortiz
SEPARATION AND PURIFICATION TECHNOLOGY
(2020)
Article
Materials Science, Multidisciplinary
Hakima Kebaili, Antonia Perez de los Rios, Maria Jose Salar-Garcia, Victor Manuel Ortiz-Martinez, Mostefa Kameche, Jesus Hernandez-Fernandez, Francisco J. Hernandez-Fernandez
FRONTIERS IN MATERIALS
(2020)
Review
Chemistry, Physical
Mohammad Bagher Karimi, Khadijeh Hooshyari, Parisa Salarizadeh, Hossein Beydaghi, V. M. Ortiz-Martinez, A. Ortiz, I. Ortiz Uribe, Fereidoon Mohammadi
Summary: This study aims to assess the proton conductivities of different proton exchange membranes and provide upper bounds for anhydrous fuel cells and high-temperature applications. Comparison of data shows that while some poly (ionic liquids) offer the highest proton conductivities, aromatic polymers like PBI are more suitable for anhydrous conditions and high temperatures.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Education, Scientific Disciplines
Guillermo Diaz-Sainz, Gema Perez, Lucia Gomez-Coma, Victor Manuel Ortiz-Martinez, Antonio Dominguez-Ramos, Raquel Ibanez, Maria J. Rivero
Summary: Mobile learning, focusing on portable technology and student mobility, is an effective method to engage students and improve learning outcomes. Case studies have demonstrated its ability to capture students' attention and promote active learning.
EDUCATION FOR CHEMICAL ENGINEERS
(2021)