Metformin Overcomes Acquired Resistance to EGFR TKIs in EGFR-Mutant Lung Cancer via AMPK/ERK/NF-κB Signaling Pathway
出版年份 2020 全文链接
标题
Metformin Overcomes Acquired Resistance to EGFR TKIs in EGFR-Mutant Lung Cancer via AMPK/ERK/NF-κB Signaling Pathway
作者
关键词
-
出版物
Frontiers in Oncology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-09-10
DOI
10.3389/fonc.2020.01605
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Therapeutic cancer prevention: achievements and ongoing challenges - a focus on breast and colorectal cancer
- (2019) Davide Serrano et al. Molecular Oncology
- Acquired resistance to EGFR targeted therapy in non-small cell lung cancer: Mechanisms and therapeutic strategies
- (2018) Sun Min Lim et al. CANCER TREATMENT REVIEWS
- Treatments for EGFR-mutant non-small cell lung cancer (NSCLC): The road to a success, paved with failures
- (2017) Dae Ho Lee PHARMACOLOGY & THERAPEUTICS
- Treatment Options for EGFR T790M-Negative EGFR Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer
- (2017) Salvatore Corallo et al. Targeted Oncology
- Acquisition of EGFR TKI resistance and EMT phenotype is linked with activation of IGF1R/NF-κB pathway in EGFR-mutant NSCLC
- (2017) Ling Li et al. Oncotarget
- Association between metformin and the risk of gastric cancer in patients with type 2 diabetes mellitus: a meta-analysis of cohort studies
- (2017) Xue-Liang Zhou et al. Oncotarget
- Metformin: A Bridge between Diabetes and Prostate Cancer
- (2017) Veronica Zingales et al. Frontiers in Oncology
- Lipopolysaccharide supports maintaining the stemness of CD133+ hepatoma cells through activation of the NF-κB/HIF-1α pathway
- (2016) Fo-Bao Lai et al. CANCER LETTERS
- Serendipity in Cancer Drug Discovery: Rational or Coincidence?
- (2016) Sahdeo Prasad et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Molecular cancer prevention: Current status and future directions
- (2015) Karen Colbert Maresso et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non-Small Cell Lung Cancer
- (2015) A. B. Lantermann et al. CANCER RESEARCH
- Cell shape and the microenvironment regulate nuclear translocation of NF- B in breast epithelial and tumor cells
- (2015) J. E. Sero et al. Molecular Systems Biology
- Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M
- (2015) Kenneth S Thress et al. NATURE MEDICINE
- Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR-Mutant Lung Cancer
- (2015) E. M. Tricker et al. Cancer Discovery
- NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer
- (2015) Collin M. Blakely et al. Cell Reports
- NF- B, an Active Player in Human Cancers
- (2014) Y. Xia et al. Cancer Immunology Research
- Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
- (2013) H. A. Hirsch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects
- (2012) Arian Emami Riedmaier et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Oncogenic EGFR Signaling Activates an mTORC2-NF- B Pathway That Promotes Chemotherapy Resistance
- (2011) K. Tanaka et al. Cancer Discovery
- Metformin inhibits P-glycoprotein expression via the NF-κB pathway and CRE transcriptional activity through AMPK activation
- (2010) Hyung Gyun Kim et al. BRITISH JOURNAL OF PHARMACOLOGY
- NF-κB promotes epithelial–mesenchymal transition, migration and invasion of pancreatic carcinoma cells
- (2010) Harald J. Maier et al. CANCER LETTERS
- Requirement of the NF-κB Subunit p65/RelA for K-Ras–Induced Lung Tumorigenesis
- (2010) Daniela S. Bassères et al. CANCER RESEARCH
- Dose translation from animal to human studies revisited
- (2007) Shannon Reagan-Shaw et al. FASEB JOURNAL
- Quantitative imaging assay for NF-κB nuclear translocation in primary human macrophages
- (2007) Mahdad Noursadeghi et al. JOURNAL OF IMMUNOLOGICAL METHODS
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