标题
Notch Signaling in Breast Cancer: A Role in Drug Resistance
作者
关键词
-
出版物
Cells
Volume 9, Issue 10, Pages 2204
出版商
MDPI AG
发表日期
2020-09-30
DOI
10.3390/cells9102204
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- DAXX-inducing phytoestrogens inhibit ER+ tumor initiating cells and delay tumor development
- (2020) Daniel S. Peiffer et al. npj Breast Cancer
- Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells
- (2019) Giuseppe Vassalli Stem Cells International
- The Central Contributions of Breast Cancer Stem Cells in Developing Resistance to Endocrine Therapy in Estrogen Receptor (ER)-Positive Breast Cancer
- (2019) David Rodriguez et al. Cancers
- DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor–Positive Breast Cancer Following Endocrine Therapy
- (2019) Daniel S. Peiffer et al. CANCER RESEARCH
- Pathways to Endocrine Therapy Resistance in Breast Cancer
- (2019) Md. Moquitul Haque et al. Frontiers in Endocrinology
- Dynamics of Phenotypic Heterogeneity during EMT and Stemness in Cancer Progression
- (2019) Jolly et al. Journal of Clinical Medicine
- T-DM1 Efficacy in Patients With HER2-positive Metastatic Breast Cancer Progressing After a Taxane Plus Pertuzumab and Trastuzumab: An Italian Multicenter Observational Study
- (2019) Benedetta Conte et al. Clinical Breast Cancer
- Incidence of Late Relapses in Patients With HER2-Positive Breast Cancer Receiving Adjuvant Trastuzumab: Combined Analysis of NCCTG N9831 (Alliance) and NRG Oncology/NSABP B-31
- (2019) Saranya Chumsri et al. JOURNAL OF CLINICAL ONCOLOGY
- Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines
- (2018) L. Gelsomino et al. CANCER LETTERS
- U.S. Food and Drug Administration Approval: Neratinib for the Extended Adjuvant Treatment of Early Stage HER2-Positive Breast Cancer
- (2018) Harpreet Singh et al. CLINICAL CANCER RESEARCH
- Inhibition of HER2 Enriches for Jagged1-dependent Breast Cancer Stem Cells: Role for Membrane Jagged1
- (2018) Deep Shah et al. CLINICAL CANCER RESEARCH
- Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival
- (2018) Andrew Baker et al. ONCOGENE
- FDA Approval Summary: Pertuzumab for adjuvant treatment of HER2-positive early breast cancer
- (2018) Lynn J. Howie et al. CLINICAL CANCER RESEARCH
- Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance)
- (2017) Matthew J. Ellis et al. JOURNAL OF CLINICAL ONCOLOGY
- Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial
- (2017) Miguel Martin et al. LANCET ONCOLOGY
- EMT and MET: necessary or permissive for metastasis?
- (2017) Mohit Kumar Jolly et al. Molecular Oncology
- Adding Adjuvant Systemic Treatment after Neoadjuvant Therapy in Breast Cancer: Review of the Data
- (2017) Shetal A. Patel et al. Current Oncology Reports
- The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis
- (2016) L. Astudillo et al. CANCER RESEARCH
- 5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, open-label, phase 2 randomised trial
- (2016) Luca Gianni et al. LANCET ONCOLOGY
- Cancer Hallmarks, Biomarkers and Breast Cancer Molecular Subtypes
- (2016) Xiaofeng Dai et al. Journal of Cancer
- A Role for Notch Signalling in Breast Cancer and Endocrine Resistance
- (2016) Ahmet Acar et al. Stem Cells International
- Response and survival of breast cancer intrinsic subtypes following multi-agent neoadjuvant chemotherapy
- (2015) Aleix Prat et al. BMC Medicine
- Picking the optimal endocrine adjuvant treatment for pre-menopausal women
- (2015) Marco Colleoni et al. BREAST
- Relationship between Complete Pathologic Response to Neoadjuvant Chemotherapy and Survival in Triple-Negative Breast Cancer
- (2015) C. Hatzis et al. CLINICAL CANCER RESEARCH
- PKC Attenuates Jagged-1-Mediated Notch Signaling in ErbB-2-Positive Breast Cancer to Reverse Trastuzumab Resistance
- (2015) K. Pandya et al. CLINICAL CANCER RESEARCH
- Epithelial-Mesenchymal Plasticity of Breast Cancer Stem Cells: Implications for Metastasis and Therapeutic Resistance
- (2015) Ming Luo et al. CURRENT PHARMACEUTICAL DESIGN
- Notch1 signaling regulates the epithelial–mesenchymal transition and invasion of breast cancer in a Slug-dependent manner
- (2015) Shan Shao et al. Molecular Cancer
- DLL4 as a predictor of pelvic lymph node metastasis and a novel prognostic biomarker in patients with early-stage cervical cancer
- (2015) Shanshan Yang et al. TUMOR BIOLOGY
- Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity
- (2015) Bruno M. Simões et al. Cell Reports
- Twist Modulates Breast Cancer Stem Cells by Transcriptional Regulation of CD24 Expression
- (2015) Farhad Vesuna et al. NEOPLASIA
- Locoregional Recurrence and Survival Outcomes by Type of Local Therapy and Trastuzumab Use Among Women with Node-Negative, HER2-Positive Breast Cancer
- (2014) David J. Peterson et al. ANNALS OF SURGICAL ONCOLOGY
- Lapatinib for the treatment of HER2-overexpressing breast cancer
- (2014) J Jones et al. HEALTH TECHNOLOGY ASSESSMENT
- Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts
- (2014) Suling Liu et al. Stem Cell Reports
- Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells
- (2013) S Suman et al. BRITISH JOURNAL OF CANCER
- Breast cancer: Current and future endocrine therapies
- (2013) Carlo Palmieri et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Targeting Notch signaling pathway in cancer: Clinical development advances and challenges
- (2013) Naoko Takebe et al. PHARMACOLOGY & THERAPEUTICS
- Combined Inhibition of ErbB1/2 and Notch Receptors Effectively Targets Breast Ductal Carcinoma In Situ (DCIS) Stem/Progenitor Cell Activity Regardless of ErbB2 Status
- (2013) Gillian Farnie et al. PLoS One
- Gamma secretase inhibitors of Notch signaling
- (2013) Clodia Osipo et al. OncoTargets and Therapy
- Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition
- (2013) Lucio Miele et al. OncoTargets and Therapy
- Probing the druggability of protein–protein interactions: targeting the Notch1 receptor ankyrin domain using a fragment-based approach
- (2012) Noha Abdel-Rahman et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Extended adjuvant endocrine therapy in hormone dependent breast cancer: The paradigm of the NCIC-CTG MA.17/BIG 1–97 trial
- (2012) Michaela J. Higgins et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- The Adjuvant Treatment of HER2-Positive Breast Cancer
- (2012) Danijela Jelovac et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- Impacts and Predictors of Cytotoxic Anticancer Agents in Different Breast Cancer Subtypes
- (2012) Takashi Ishikawa et al. ONCOLOGY RESEARCH
- Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations
- (2012) Nelson K. Y. Wong et al. Cancer Medicine
- Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence
- (2011) K Pandya et al. BRITISH JOURNAL OF CANCER
- One NOTCH Further: Jagged 1 in Bone Metastasis
- (2011) Jianning Tao et al. CANCER CELL
- Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells
- (2011) Nilay Sethi et al. CANCER CELL
- Notch signaling: simplicity in design, versatility in function
- (2011) E. R. Andersson et al. DEVELOPMENT
- Notch-1 and Notch-4 Biomarker Expression in Triple-Negative Breast Cancer
- (2011) Jodi Speiser et al. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
- Down regulation of CSL activity inhibits cell proliferation in prostate and breast cancer cells
- (2011) Thomas Yong et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- A Monoclonal Antibody against Human Notch1 Ligand-Binding Domain Depletes Subpopulation of Putative Breast Cancer Stem-like Cells
- (2011) A. Sharma et al. MOLECULAR CANCER THERAPEUTICS
- Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer
- (2011) M Kondratyev et al. ONCOGENE
- Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells
- (2011) F Xing et al. ONCOGENE
- Role of Notch and its oncogenic signaling crosstalk in breast cancer
- (2010) Shanchun Guo et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Triple negative breast cancer: unmet medical needs
- (2010) Sumanta Kumar Pal et al. BREAST CANCER RESEARCH AND TREATMENT
- Breast Cancer Stem Cells: Something Out of Notching?
- (2010) H. Harrison et al. CANCER RESEARCH
- Targeting Notch to Target Cancer Stem Cells
- (2010) A. Pannuti et al. CLINICAL CANCER RESEARCH
- Notch-1 and Notch-4 Receptors as Prognostic Markers in Breast Cancer
- (2010) Katharine Yao et al. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
- Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
- (2010) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancer
- (2009) Brenda Cohen et al. BREAST CANCER RESEARCH AND TREATMENT
- Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
- (2009) J Chen et al. BRITISH JOURNAL OF CANCER
- Translational Activation of Snail1 and Other Developmentally Regulated Transcription Factors by YB-1 Promotes an Epithelial-Mesenchymal Transition
- (2009) Valentina Evdokimova et al. CANCER CELL
- Breast Cancer Metastasis: Challenges and Opportunities
- (2009) J. Lu et al. CANCER RESEARCH
- Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
- (2009) Emmanuelle Charafe-Jauffret et al. CANCER RESEARCH
- The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
- (2009) Raphael Kopan et al. CELL
- The Notch signaling pathway: Transcriptional regulation at Notch target genes
- (2009) T. Borggrefe et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Tumor-Initiating Cells of HER2-Positive Carcinoma Cell Lines Express the Highest Oncoprotein Levels and Are Sensitive to Trastuzumab
- (2009) A. Magnifico et al. CLINICAL CANCER RESEARCH
- Association of Breast Cancer Stem Cells Identified by Aldehyde Dehydrogenase 1 Expression with Resistance to Sequential Paclitaxel and Epirubicin-Based Chemotherapy for Breast Cancers
- (2009) T. Tanei et al. CLINICAL CANCER RESEARCH
- Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer
- (2009) E. Charafe-Jauffret et al. CLINICAL CANCER RESEARCH
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Direct inhibition of the NOTCH transcription factor complex
- (2009) Raymond E. Moellering et al. NATURE
- Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance
- (2008) W. Matsui et al. CANCER RESEARCH
- Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches
- (2008) P. Rizzo et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- ErbB2 Induces Notch1 Activity and Function in Breast Cancer Cells
- (2008) Jaime Lindsay et al. CTS-Clinical and Translational Science
- Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy
- (2008) X. Li et al. JNCI-Journal of the National Cancer Institute
- ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor
- (2008) C Osipo et al. ONCOGENE
- Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
- (2008) Anne-Pierre Morel et al. PLoS One
- Notch signaling mediates hypoxia-induced tumor cell migration and invasion
- (2008) C. Sahlgren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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