NK-Cell-Mediated Targeting of Various Solid Tumors Using a B7-H3 Tri-Specific Killer Engager In Vitro and In Vivo
出版年份 2020 全文链接
标题
NK-Cell-Mediated Targeting of Various Solid Tumors Using a B7-H3 Tri-Specific Killer Engager In Vitro and In Vivo
作者
关键词
-
出版物
Cancers
Volume 12, Issue 9, Pages 2659
出版商
MDPI AG
发表日期
2020-09-18
DOI
10.3390/cancers12092659
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Potent Cytolytic Activity and Specific IL15 Delivery in a 2nd Generation Trispecific Killer Engager
- (2020) Martin Felices et al. Cancer Immunology Research
- Cytokine-induced memory-like natural killer cells have enhanced function, proliferation, and in vivo expansion against ovarian cancer cells
- (2019) Locke D. Uppendahl et al. GYNECOLOGIC ONCOLOGY
- Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells
- (2019) Hongwei Du et al. CANCER CELL
- Pluripotent stem cell–derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity
- (2019) Huang Zhu et al. BLOOD
- First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation
- (2018) Rizwan Romee et al. BLOOD
- B7-H3 in tumors: friend or foe for tumor immunity?
- (2018) Gen Li et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial
- (2018) Mark M Souweidane et al. LANCET ONCOLOGY
- B7H3 As a Promoter of Metastasis and Promising Therapeutic Target
- (2018) Peixin Dong et al. Frontiers in Oncology
- IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer
- (2017) M. Felices et al. GYNECOLOGIC ONCOLOGY
- Tumor B7-H3 (CD276) expression and smoking history in relation to lung adenocarcinoma prognosis
- (2017) Kentaro Inamura et al. LUNG CANCER
- Engineering of Anti-CD133 Trispecific Molecule Capable of Inducing NK Expansion and Driving Antibody-Dependent Cell-Mediated Cytotoxicity
- (2017) Jörg U. Schmohl et al. Cancer Research and Treatment
- IL15 Infusion of Cancer Patients Expands the Subpopulation of Cytotoxic CD56 bright NK Cells and Increases NK-Cell Cytokine Release Capabilities
- (2017) Sigrid Dubois et al. Cancer Immunology Research
- NK Cell Exhaustion
- (2017) Jiacheng Bi et al. Frontiers in Immunology
- IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function
- (2016) D. A. Vallera et al. CLINICAL CANCER RESEARCH
- Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy
- (2016) E. Picarda et al. CLINICAL CANCER RESEARCH
- Targeting ADAM17 Sheddase Activity in Cancer
- (2016) Armando Rossello et al. CURRENT DRUG TARGETS
- Enhanced ADCC and NK Cell Activation of an Anticarcinoma Bispecific Antibody by Genetic Insertion of a Modified IL-15 Cross-linker
- (2016) Joerg U Schmohl et al. MOLECULAR THERAPY
- Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: an expression-based analysis
- (2016) B Benzon et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker
- (2016) Joerg U. Schmohl et al. Oncotarget
- Blinatumomab: A novel, bispecific, T-cell engaging antibody
- (2015) M. B. May et al. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
- Heterodimeric Bispecific Single Chain Variable Fragments (scFv) Killer Engagers (BiKEs) Enhance NK-cell Activity Against CD133+ Colorectal Cancer Cells
- (2015) J. U. Schmohl et al. Targeted Oncology
- Comparison of the Superagonist Complex, ALT-803, to IL15 as Cancer Immunotherapeutics in Animal Models
- (2015) P. R. Rhode et al. Cancer Immunology Research
- Identification of an ADAM17 Cleavage Region in Human CD16 (FcγRIII) and the Engineering of a Non-Cleavable Version of the Receptor in NK Cells
- (2015) Yawu Jing et al. PLoS One
- CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets
- (2014) M. K. Gleason et al. BLOOD
- Safety profile of long-term intraventricular access devices in pediatric patients receiving radioimmunotherapy for central nervous system malignancies
- (2014) Kim Kramer et al. PEDIATRIC BLOOD & CANCER
- NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)
- (2013) R. Romee et al. BLOOD
- Toxicity management for patients receiving novel T-cell engaging therapies
- (2013) David M. Barrett et al. CURRENT OPINION IN PEDIATRICS
- Monoclonal antibody-based immunotherapy of ovarian cancer: Targeting ovarian cancer cells with the B7-H3-specific mAb 376.96
- (2013) Janelle M. Fauci et al. GYNECOLOGIC ONCOLOGY
- Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients
- (2013) Branka Petricevic et al. Journal of Translational Medicine
- Structure and T Cell Inhibition Properties of B7 Family Member, B7-H3
- (2013) Vladimir Vigdorovich et al. STRUCTURE
- The role of B7 family molecules in hematologic malignancy
- (2012) P. Greaves et al. BLOOD
- Development of an Fc-Enhanced Anti-B7-H3 Monoclonal Antibody with Potent Antitumor Activity
- (2012) D. Loo et al. CLINICAL CANCER RESEARCH
- Induced expression of B7-H3 on the lung cancer cells and macrophages suppresses T-cell mediating anti-tumor immune response
- (2012) Cheng Chen et al. EXPERIMENTAL CELL RESEARCH
- A review of B7-H3 and B7-H4 immune molecules and their role in ovarian cancer
- (2012) Janelle M. Fauci et al. GYNECOLOGIC ONCOLOGY
- Clinical Cancer Therapy by NK Cells via Antibody-Dependent Cell-Mediated Cytotoxicity
- (2011) Kory L. Alderson et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- B7-H3 and Its Role in Antitumor Immunity
- (2010) Martin Loos et al. Clinical & Developmental Immunology
- NK cell dysfunction with down-regulated CD16 and up-regulated CD56 molecules in patients with esophageal squamous cell carcinoma
- (2010) M. Watanabe et al. DISEASES OF THE ESOPHAGUS
- Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas
- (2010) Xingxing Zang et al. MODERN PATHOLOGY
- Clinical importance of B7-H3 expression in human pancreatic cancer
- (2009) I Yamato et al. BRITISH JOURNAL OF CANCER
- Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma
- (2009) Kim Kramer et al. JOURNAL OF NEURO-ONCOLOGY
- General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold
- (2008) Cécile Vincke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The contrasting role of B7-H3
- (2008) K. A. Hofmeyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started