Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction

标题
Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction
作者
关键词
Acute lung injury (ALI), Acute respiratory distress syndrome (ARDS), NADPH oxidase (NOX), NOX1, NOX2, NOX4, p22phox, p47phox, Reactive oxygen species (ROS), Endothelial cell (EC), Endothelial barrier dysfunction, Endothelial permeability, Tight junction, ZO-1, Occludin
出版物
Redox Biology
Volume 36, Issue -, Pages 101638
出版商
Elsevier BV
发表日期
2020-07-13
DOI
10.1016/j.redox.2020.101638

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