The Effect of Rev-erbα Agonist SR9011 on the Immune Response and Cell Metabolism of Microglia

The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia

(2020) Gareth B. Kitchen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An evolutionary perspective on immunometabolism

(2019) Andrew Wang et al.   SCIENCE

Circadian clock protein Rev-erbα regulates neuroinflammation

(2019) Percy Griffin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SR9009 has REV-ERB–independent effects on cell proliferation and metabolism

(2019) Pieterjan Dierickx et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia immunometabolism: From metabolic disorders to single cell metabolism

(2019) Rosa C. Paolicelli et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner

(2019) Irina V. Milanova et al.   Frontiers in Endocrinology

Pharmacological activation of REV-ERBα represses LPS-induced microglial activation through the NF-κB pathway

(2018) Dong-kai Guo et al.   ACTA PHARMACOLOGICA SINICA

Potential Roles of Dec and Bmal1 Genes in Interconnecting Circadian Clock and Energy Metabolism

(2018) Fuyuki Sato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular Cogs: Interplay between Circadian Clock and Cell Cycle

(2018) Jonathan Gaucher et al.   TRENDS IN CELL BIOLOGY

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence

(2018) Gabriele Sulli et al.   NATURE

Microglia metabolism in health and disease

(2018) Katharina Borst et al.   NEUROCHEMISTRY INTERNATIONAL

Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

(2017) Nathalia R. V. Dragano et al.   Journal of Neuroinflammation

TNFα drives mitochondrial stress in POMC neurons in obesity

(2017) Chun-Xia Yi et al.   Nature Communications

Microglia activation due to obesity programs metabolic failure leading to type two diabetes

(2017) R Maldonado-Ruiz et al.   Nutrition & Diabetes

Dietary sugars, not lipids, drive hypothalamic inflammation

(2017) Yuanqing Gao et al.   Molecular Metabolism

The intrinsic microglial clock system regulates interleukin-6 expression

(2016) Ryota Nakazato et al.   GLIA

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR) Axis

(2015) Di Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic Consequences of Sleep and Circadian Disorders

(2014) Christopher M. Depner et al.   Current Diabetes Reports

Nuclear receptor Rev-erbα: up, down, and all around

(2014) Logan J. Everett et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function

(2014) Martin Valdearcos et al.   Cell Reports

Spare mitochondrial respiratory capacity permits human adipocytes to maintain ATP homeostasis under hypoglycemic conditions

(2013) Michaela Keuper et al.   FASEB JOURNAL

Hormones and diet, but not body weight, control hypothalamic microglial activity

(2013) Yuanqing Gao et al.   GLIA

Rev-erbα regulates circadian rhythms and StAR expression in rat granulosa cells as identified by the agonist GSK4112

(2012) Huatao Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rev-erb  and Rev-erb  coordinately protect the circadian clock and normal metabolic function

(2012) A. Bugge et al.   GENES & DEVELOPMENT

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Selective Upregulation of Per1 mRNA Expression by ATP Through Activation of P2X7 Purinergic Receptors Expressed in Microglial Cells

(2011) Ryota Nakazato et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Circadian nature of immune function

(2011) Ryan W. Logan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Direct Regulation of CLOCK Expression by REV-ERB

(2011) Christine Crumbley et al.   PLoS One

Deficient of a Clock Gene, Brain and Muscle Arnt-Like Protein-1 (BMAL1), Induces Dyslipidemia and Ectopic Fat Formation

(2011) Shigeki Shimba et al.   PLoS One

GSK4112, a Small Molecule Chemical Probe for the Cell Biology of the Nuclear Heme Receptor Rev-erbα

(2010) Daniel Grant et al.   ACS Chemical Biology

Identification of SR8278, a Synthetic Antagonist of the Nuclear Heme Receptor REV-ERB

(2010) Douglas Kojetin et al.   ACS Chemical Biology

JTK_CYCLE: An Efficient Nonparametric Algorithm for Detecting Rhythmic Components in Genome-Scale Data Sets

(2010) Michael E. Hughes et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

Negative feedback maintenance of heme homeostasis by its receptor, Rev-erb 

(2009) N. Wu et al.   GENES & DEVELOPMENT