Radiosensitizing high-Z metal nanoparticles for enhanced radiotherapy of glioblastoma multiforme

Chemical Mechanisms of Nanoparticle Radiosensitization and Radioprotection: A Review of Structure-Function Relationships Influencing Reactive Oxygen Species

(2020) Douglas Howard et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting hallmarks of cancer to enhance radiosensitivity in gastrointestinal cancers

(2020) Amy M. Buckley et al.   Nature Reviews Gastroenterology & Hepatology

Differential effects of the Akt inhibitor MK-2206 on migration and radiation sensitivity of glioblastoma cells

(2019) Cholpon S. Djuzenova et al.   BMC CANCER

Gold Nanoparticles for Photothermal Cancer Therapy

(2019) Jeremy B. Vines et al.   Frontiers in Chemistry

Elucidating the Inability of Functionalized Nanoparticles to Cross the Blood–Brain Barrier and Target Specific Cells in Vivo

(2019) Priya S. R. Naidu et al.   ACS Applied Materials & Interfaces

NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2–3, randomised, controlled trial

(2019) Sylvie Bonvalot et al.   LANCET ONCOLOGY

Radiosensitization of high-grade gliomas through induced hyperthermia: Review of clinical experience and the potential role of MR-guided focused ultrasound

(2019) Craig S. Schneider et al.   RADIOTHERAPY AND ONCOLOGY

DNA damage enhancement by radiotherapy-activated hafnium oxide nanoparticles improves cGAS-STING pathway activation in human colorectal cancer cells

(2019) Julie Marill et al.   RADIOTHERAPY AND ONCOLOGY

NaCeF4:Gd,Tb Scintillator as an X-ray Responsive Photosensitizer for Multimodal Imaging-Guided Synchronous Radio/Radiodynamic Therapy

(2019) Xiaoyan Zhong et al.   NANO LETTERS

Radiosensitizing Effect of Gadolinium Oxide Nanocrystals in NSCLC Cells Under Carbon Ion Irradiation

(2019) Feifei Li et al.   Nanoscale Research Letters

Nanomaterial-based blood-brain-barrier (BBB) crossing strategies

(2019) Jinbing Xie et al.   BIOMATERIALS

H1/pHGFK1 nanoparticles exert anti-tumoural and radiosensitising effects by inhibition of MET in glioblastoma

(2018) Wenyan Zhang et al.   BRITISH JOURNAL OF CANCER

Octaarginine-modified gold nanoparticles enhance the radiosensitivity of human colorectal cancer cell line LS180 to megavoltage radiation

(2018) Xuyang Zhang et al.   International Journal of Nanomedicine

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

Metal-based NanoEnhancers for Future Radiotherapy: Radiosensitizing and Synergistic Effects on Tumor Cells

(2018) Yan Liu et al.   Theranostics

Iridium nanocrystals encapsulated liposomes as near-infrared light controllable nanozymes for enhanced cancer radiotherapy

(2018) Liangzhu Feng et al.   BIOMATERIALS

A gold nanoparticle system for enhancement of radiotherapy and simultaneous monitoring of reactive-oxygen-species formation

(2018) Jihye Choi et al.   NANOTECHNOLOGY

Disulfiram, a Re-positioned Aldehyde Dehydrogenase Inhibitor, Enhances Radiosensitivity of Human Glioblastoma Cells In Vitro

(2018) Hyeon Kang Koh et al.   Cancer Research and Treatment

Approaches to physical stimulation of metallic nanoparticles for glioblastoma treatment

(2018) Sophie Pinel et al.   ADVANCED DRUG DELIVERY REVIEWS

Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy

(2018) Ziliang Dong et al.   NANO LETTERS

Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma

(2017) Eloïse Thomas et al.   International Journal of Nanomedicine

GBM radiosensitizers: dead in the water…or just the beginning?

(2017) Ranjit S. Bindra et al.   JOURNAL OF NEURO-ONCOLOGY

Surface plasmon resonance in gold nanoparticles: a review

(2017) Vincenzo Amendola et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Realizing the therapeutic potential of rare earth elements in designing nanoparticles to target and treat glioblastoma

(2017) Victor M Lu et al.   Nanomedicine

68Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy

(2017) Penelope Bouziotis et al.   Nanomedicine

Gold nanotriangles: scale up and X-ray radiosensitization effects in mice

(2017) S. R. Bhattarai et al.   Nanoscale

CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014

(2017) Quinn T Ostrom et al.   NEURO-ONCOLOGY

Re-assessing the enhanced permeability and retention effect in peripheral arterial disease using radiolabeled long circulating nanoparticles

(2016) Christopher G. England et al.   BIOMATERIALS

Nanoparticles in radiation oncology: From bench-side to bedside

(2016) Chloé Rancoule et al.   CANCER LETTERS

Nanostructured lipid carriers, solid lipid nanoparticles, and polymeric nanoparticles: which kind of drug delivery system is better for glioblastoma chemotherapy?

(2016) Jie Qu et al.   DRUG DELIVERY

Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma

(2016) Pei Dang Liu et al.   International Journal of Nanomedicine

Polyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis

(2016) Yinghua Li et al.   International Journal of Nanomedicine

Theranostic Application of Mixed Gold and Superparamagnetic Iron Oxide Nanoparticle Micelles in Glioblastoma Multiforme

(2016) Lova Sun et al.   Journal of Biomedical Nanotechnology

Nanoparticles for brain-specific drug and genetic material delivery, imaging and diagnosis

(2016) Inmaculada Posadas et al.   Nanomedicine

Optimizing dose enhancement with Ta 2 O 5 nanoparticles for synchrotron microbeam activated radiation therapy

(2016) Elette Engels et al.   Physica Medica-European Journal of Medical Physics

First proof of bismuth oxide nanoparticles as efficient radiosensitisers on highly radioresistant cancer cells

(2016) Callum Stewart et al.   Physica Medica-European Journal of Medical Physics

Effect of gadolinium-based nanoparticles on nuclear DNA damage and repair in glioblastoma tumor cells

(2016) Lenka Štefančíková et al.   JOURNAL OF NANOBIOTECHNOLOGY

Clearance Pathways and Tumor Targeting of Imaging Nanoparticles

(2015) Mengxiao Yu et al.   ACS Nano

Altered protein expression profile associated with phenotypic changes in lung fibroblasts co-cultured with gold nanoparticle-treated small airway epithelial cells

(2015) Cheng-Teng Ng et al.   BIOMATERIALS

Radiosensitivity enhancement of radioresistant glioblastoma by epidermal growth factor receptor antibody-conjugated iron-oxide nanoparticles

(2015) Alexandros Bouras et al.   JOURNAL OF NEURO-ONCOLOGY

Enhancing Glioblastoma-Specific Penetration by Functionalization of Nanoparticles with an Iron-Mimic Peptide Targeting Transferrin/Transferrin Receptor Complex

(2015) Ting Kang et al.   MOLECULAR PHARMACEUTICS

Ionizing radiation improves glioma-specific targeting of superparamagnetic iron oxide nanoparticles conjugated with cmHsp70.1 monoclonal antibodies (SPION–cmHsp70.1)

(2015) Maxim A. Shevtsov et al.   Nanoscale

Opportunities and challenges of radiotherapy for treating cancer

(2015) Dörthe Schaue et al.   Nature Reviews Clinical Oncology

Cancer Therapeutic Effects of Titanium Dioxide Nanoparticles Are Associated with Oxidative Stress and Cytokine Induction

(2015) Rina Fujiwara et al.   PATHOBIOLOGY

Enhanced production of reactive oxygen species by gadolinium oxide nanoparticles under core–inner-shell excitation by proton or monochromatic X-ray irradiation: implication of the contribution from the interatomic de-excitation-mediated nanoradiator effect to dose enhancement

(2015) Seung-Jun Seo et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

Sensitive detection of carcinoembryonic antigen using surface plasmon resonance biosensor with gold nanoparticles signal amplification

(2015) Rong Li et al.   TALANTA

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

BSA capped Au nanoparticle as an efficient sensitizer for glioblastoma tumor radiation therapy

(2015) Na Chen et al.   RSC Advances

The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy

(2014) L Sancey et al.   BRITISH JOURNAL OF RADIOLOGY

Combined concurrent photodynamic and gold nanoshell loaded macrophage-mediated photothermal therapies: Anin vitrostudy on squamous cell head and neck carcinoma

(2014) Anthony J. Trinidad et al.   LASERS IN SURGERY AND MEDICINE

RGD and Interleukin-13 Peptide Functionalized Nanoparticles for Enhanced Glioblastoma Cells and Neovasculature Dual Targeting Delivery and Elevated Tumor Penetration

(2014) Huile Gao et al.   MOLECULAR PHARMACEUTICS

Cisplatin-tethered gold nanospheres for multimodal chemo-radiotherapy of glioblastoma

(2014) Sonali Setua et al.   Nanoscale

Enhancing radiation therapy for patients with glioblastoma

(2013) Brian M Alexander et al.   Expert Review of Anticancer Therapy

Biosynthesis of silver nanoparticles: Elucidation of prospective mechanism and therapeutic potential

(2013) Amit Kumar Mittal et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Silver nanoparticles: a novel radiation sensitizer for glioma?

(2013) Peidang Liu et al.   Nanoscale

In vitro and in vivo radiosensitization induced by hydroxyapatite nanoparticles

(2013) S.-H. Chu et al.   NEURO-ONCOLOGY

High-Z Nanostructured Ceramics in Radiotherapy: First Evidence of Ta2O5-Induced Dose Enhancement on Radioresistant Cancer Cells in an MV Photon Field

(2013) Ryan Brown et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Selective Targeting of Brain Tumors with Gold Nanoparticle-Induced Radiosensitization

(2013) Daniel Y. Joh et al.   PLoS One

The radiosensitization effect of titanate nanotubes as a new tool in radiation therapy for glioblastoma: A proof-of-concept

(2013) C. Mirjolet et al.   RADIOTHERAPY AND ONCOLOGY

New Paradigms and Future Challenges in Radiation Oncology: An Update of Biological Targets and Technology

(2013) S. L. Liauw et al.   Science Translational Medicine

Computed tomography imaging-guided radiotherapy by targeting upconversion nanocubes with significant imaging and radiosensitization enhancements

(2013) Huaiyong Xing et al.   Scientific Reports

Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization

(2013) Huile Gao et al.   Scientific Reports

Highly sensitive detection of human cardiac myoglobin using a reverse sandwich immunoassay with a gold nanoparticle-enhanced surface plasmon resonance biosensor

(2012) Oksana V. Gnedenko et al.   ANALYTICA CHIMICA ACTA

Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles

(2012) Fan Zhang et al.   BIOMATERIALS

Neurotoxicity of Engineered Nanoparticles from Metals

(2012) Hari Shanker Sharma et al.   CNS & Neurological Disorders-Drug Targets

Motexafin-Gadolinium and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood: A Children's Oncology Group Phase 2 Study

(2012) Kristin A. Bradley et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Nanoparticle Location and Material-Dependent Dose Enhancement in X-ray Radiation Therapy

(2012) Mainul Hossain et al.   Journal of Physical Chemistry C

Physical basis and biological mechanisms of gold nanoparticle radiosensitization

(2012) Karl T. Butterworth et al.   Nanoscale

Toward an Image-Guided Microbeam Radiation Therapy Using Gadolinium-Based Nanoparticles

(2011) Géraldine Le Duc et al.   ACS Nano

Photothermal Cancer Therapy and Imaging Based on Gold Nanorods

(2011) Won Il Choi et al.   ANNALS OF BIOMEDICAL ENGINEERING

Generation of reactive oxygen species induced by gold nanoparticles under x-ray and UV Irradiations

(2011) Masaki Misawa et al.   Nanomedicine-Nanotechnology Biology and Medicine

Silver nanoparticle applications and human health

(2010) Maqusood Ahamed et al.   CLINICA CHIMICA ACTA

Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme

(2010) Klaus Maier-Hauff et al.   JOURNAL OF NEURO-ONCOLOGY

Enhancement of radiation effect by heavy elements

(2010) K. Kobayashi et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Gold Nanoparticles as Radiation Sensitizers in Cancer Therapy

(2010) Devika B. Chithrani et al.   RADIATION RESEARCH

Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide

(2010) Giuseppe Minniti et al.   RADIOTHERAPY AND ONCOLOGY

The Role of Surface Functionality on Acute Cytotoxicity, ROS Generation and DNA Damage by Cationic Gold Nanoparticles

(2010) Apiwat Chompoosor et al.   Small

Nanosilver as a new generation of nanoproduct in biomedical applications

(2010) Karla Chaloupka et al.   TRENDS IN BIOTECHNOLOGY

Ag nanoparticles sensitize IR-induced killing of cancer cells

(2009) Ruizhi Xu et al.   CELL RESEARCH

Glioblastoma multiforme: a review of where we have been and where we are going

(2009) Cory Adamson et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Influence of Engineered Nanoparticles from Metals on the Blood-Brain Barrier Permeability, Cerebral Blood Flow, Brain Edema and Neurotoxicity. An Experimental Study in the Rat and Mice Using Biochemical and Morphological Approaches

(2009) Hari S. Sharma et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Concomitant treatment of F98 glioma cells with new liposomal platinum compounds and ionizing radiation

(2009) Gabriel Charest et al.   JOURNAL OF NEURO-ONCOLOGY

Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle

(2009) Wilson Roa et al.   NANOTECHNOLOGY

Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies

(2008) Liv Veldeman et al.   LANCET ONCOLOGY