Article
Environmental Sciences
Neha Arora, George P. Philippidis
Summary: The study reveals that Chlorella vulgaris exhibits better nutrient stress tolerance and redox balancing under mixotrophic conditions, leading to higher biomass and lipid production.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Biochemistry & Molecular Biology
Michal Levin, Falk Butter
Summary: Applications in omics research benefit from comprehensive high-quality annotation of coding genes. Transcriptome provides the optimal basis for identifying open reading frames, and the integration of proteomics data enriches for accurate gene models.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2022)
Review
Plant Sciences
Xiangyu Xu, Cassio Flavio Fonseca de Lima, Lam Dai Vu, Ive De Smet
Summary: Changes in weather patterns, drought risks, and rising global temperature negatively impact crop growth and productivity. Plants are exposed to multiple stresses simultaneously, but most studies focus on individual stress conditions. This mini-review focuses on the combination of drought and heat, summarizing current research results, identifying knowledge gaps, and suggesting potential future focus areas.
FRONTIERS IN PLANT SCIENCE
(2023)
Review
Food Science & Technology
Karolinny Cristiny de Oliveira Vieira, Hevelin Regiane Augusto da Silva, Isabela Poletto Masselli Rocha, Emmanuel Barboza, Lizziane Kretli Winkelstroter Eller
Summary: Outbreaks and deaths related to Foodborne Diseases (FBD) are constantly occurring worldwide, largely due to consumption of contaminated foodstuffs with pathogens. This review discusses the main omic techniques applied in foodborne pathogens and their potential in ensuring food safety. Omics have been shown to integrate variables that contribute to food safety and improve consumer health, costs, and product quality.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Medicine, Research & Experimental
Chang-Zhu Pei, Lan Jin, Kwang-Hyun Baek
Summary: PCOS is a common gynecological endocrine disease involving multiple genes and pathways, and cannot be explained by a single factor. Omics analysis plays a key role in studying the pathogenesis of PCOS, offering new perspectives for explaining new mechanisms and potential biomarkers discovery.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Review
Plant Sciences
Deepmala Sehgal, Priyanka Dhakate, Heena Ambreen, Khasim Hussain Baji Shaik, Nagenahalli Dharmegowda Rathan, Nayanahalli Munireddy Anusha, Rupesh Deshmukh, Prashant Vikram
Summary: Plant omics has played a crucial role in discovering new genes and biomolecules that can improve crops, and has made significant progress in wheat research on both qualitative and quantitative traits. Combining various omics approaches has led to advances in gene discovery, pathway investigation, and understanding stress responses and yields. The development of a Wheat Omics database further aids functional genomics studies in wheat.
Review
Biotechnology & Applied Microbiology
Ranjna Sirohi, Jaemin Joun, Hong Ii Choi, Vivek Kumar Gaur, Sang Jun Sim
Summary: This article discusses the potential of microalgae as an energy feedstock and the efforts to increase microalgae productivity using various omics techniques, with a particular focus on the application of genome sequencing and metabolic engineering in this field.
MICROBIAL CELL FACTORIES
(2021)
Review
Biotechnology & Applied Microbiology
Alexander Arsov, Kaloyan Petrov, Penka Petrova
Summary: This article discusses the potential of microbial production of butanol as a new fuel and the challenge of butanol toxicity to microbes. Modern omics approaches have made significant progress in addressing the issue of low butanol tolerance, but a strain capable of both synthesis and tolerance at commercializable concentrations has yet to be discovered or produced.
BIOTECHNOLOGY ADVANCES
(2021)
Review
Pharmacology & Pharmacy
Mengyuan Kan, Blanca E. Himes
Summary: Glucocorticoid drugs are widely used in the treatment of diseases, but there is still much to learn about their cell type-specific mechanisms and why patients respond differently. Recent studies have used genomics, transcriptomics, and other omics approaches to address these questions, but there are still knowledge gaps to be filled related to glucocorticoid action mechanisms.
PHARMACOLOGY & THERAPEUTICS
(2021)
Review
Biochemistry & Molecular Biology
Qiaolifan Aerqin, Zuo-Teng Wang, Kai-Min Wu, Xiao-Yu He, Qiang Dong, Jin-Tai Yu
Summary: This review summarizes the progress made in the discovery of reliable Alzheimer's disease (AD) biomarkers using genomics, transcriptomics, proteomics, and metabolomics. The importance of these biomarkers in the diagnosis and treatment of AD is discussed.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2022)
Review
Food Science & Technology
Anastasios Tsoungos, Violeta Pemaj, Aleksandra Slavko, John Kapolos, Marina Papadelli, Konstantinos Papadimitriou
Summary: This review explores recent advances in table olive research through omics and meta-omics approaches, offering insights into the genomic, metagenomic, and metabolomic analysis of the microbial community in table olives. These methods hold the promise of groundbreaking advances in table olive processing technology.
Review
Plant Sciences
Umer Mahmood, Xiaodong Li, Yonghai Fan, Wei Chang, Yue Niu, Jiana Li, Cunmin Qu, Kun Lu
Summary: Crop production is facing challenges from increasing food demand and climate change. Advances in omics techniques and machine learning algorithms can accelerate crop breeding to cope with these challenges. Plant breeding and genetic engineering can develop nutrient sufficient and climate-resilient crops.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Cell Biology
Jia-Chen Liu, Shan-Shan Dong, Hui Shen, Dan-Yue Yang, Bin-Bin Chen, Xue-Ying Ma, Yi-Ran Peng, Hong-Mei Xiao, Hong-Wen Deng
Summary: Sarcopenia is a systemic disease characterized by muscle dysfunction, with its genetic architecture and molecular mechanisms still largely unclear. Recent advancements in multi-omics studies offer new insights into the pathogenesis of sarcopenia and may lead to new clinical applications.
AGEING RESEARCH REVIEWS
(2022)
Article
Cell Biology
Di Peng, Chen Ruan, Shanshan Fu, Chengwen He, Jingzhen Song, Hui Li, Yiran Tu, Dachao Tang, Lan Yao, Shaofeng Lin, Ying Shi, Weizhi Zhang, Hao Zhou, Le Zhu, Cong Ma, Cheng Chang, Jie Ma, Zhiping Xie, Chenwei Wang, Yu Xue
Summary: A multi-omic profiling revealed the influence of Atg9 on gene expression during autophagy and predicted 42 potential new Atg9-interacting proteins involved in autophagy. Two of these proteins, Glo3 and Scs7, were validated to be functional in autophagy, with Glo3 regulating the retrograde transport of Atg9. The study highlighted the importance of the Atg9 interactome and introduced a new method for analyzing multi-omics data.
Review
Plant Sciences
Milan Jockovic, Sinisa Jocic, Sandra Cvejic, Ana Marjanovic-Jeromela, Jelena Jockovic, Aleksandra Radanovic, Dragana Miladinovic
Summary: The review emphasizes the importance of systematic approaches to sunflower breeding, highlighting the lack of desirable genetic variation in the field. By integrating information from various omics technologies, a comprehensive understanding of the molecular mechanisms in sunflower can be achieved, leading to more efficient breeding strategies.
Article
Energy & Fuels
Jenniffer Andrea Tamayo Pena, Livia Caldas Alencar Pacheco, Laura Plazas Tovar, Telma Teixeira Franco
Summary: The thermal decomposition of lipids from microorganisms like C. vulgaris and L. starkeyi were studied using TGA-MS, revealing differences in activation energy and decomposition mechanisms. This research provides valuable insights for the production of lipid-based building blocks from microbial biomass.
BIOENERGY RESEARCH
(2022)
Article
Energy & Fuels
Maria Paula. C. Volpi, Livia B. Brenelli, Gustavo Mockaitis, Sarita C. Rabelo, Telma T. Franco, Bruna S. Moraes
Summary: This pioneer study evaluates the methane production potential from residues of integrated first and second generation sugarcane biorefinery, showing that co-digestion optimization enhances methane yield and reduces energy consumption.
BIOENERGY RESEARCH
(2022)
Article
Multidisciplinary Sciences
Carolina da Silveira Bueno, Fabio Kenji Masago, Jose Maria Ferreira Jardim da Silveira, Bruna de Souza Moraes, Leonardo Brantes Bacellar Mendes, Ivette Raymunda Luna
Summary: This paper examines the collaboration dynamic among areas of knowledge and countries within the bioenergy field from 1975 to 2017, using a complex network approach. The results show a pattern of intensified collaboration and interdependence among various areas of knowledge and countries, particularly in the biotechnology field. This study aims to stimulate debate on innovation dynamics within a complex network perspective and provide support for policymakers in bioeconomy innovation systems.
AFRICAN JOURNAL OF SCIENCE TECHNOLOGY INNOVATION & DEVELOPMENT
(2022)
Article
Biochemistry & Molecular Biology
Sandra Gonzalez-Sayer, Ursula Oggenfuss, Ibonne Garcia, Fabio Aristizabal, Daniel Croll, Diego M. Riano-Pachon
Summary: In this study, we successfully assembled and annotated the genome of Pseudocercospora ulei, the causal agent of South American Leaf Blight (SALB) in rubber trees. The assembled genome is of high quality, making it the largest among Mycosphaerellaceae and containing a high proportion of retrotransposons. This research provides essential genomic resources for future studies on P. ulei and related species.
GENETICS AND MOLECULAR BIOLOGY
(2022)
Article
Plant Sciences
Daniele Paschoal, Juliana L. Costa, Eder M. da Silva, Fabia B. da Silva, Diogo Capelin, Vitor Ometto, Juliana A. Aricetti, Gabriel G. Carvalho, Rodrigo F. Pimpinato, Ricardo F. de Oliveira, Esther Carrera, Isabel Lopez-Diaz, Monica L. Rossi, Valdemar Tornisielo, Camila Caldana, Diego M. Riano-Pachon, Igor Cesarino, Paulo J. P. L. Teixeira, Antonio Figueira
Summary: Using tomato as a model system, this study investigates the physiological and metabolic consequences of Moniliophthora perniciosa infection, suggesting that symptoms result from sink establishment by the pathogen.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Review
Biotechnology & Applied Microbiology
Dielle Pierotti Procopio, Emanuele Kendrick, Rosana Goldbeck, Andre Ricardo de Lima Damasio, Telma Teixeira Franco, David J. Leak, Yong-Su Jin, Thiago Olitta Basso
Summary: The engineering of xylo-oligosaccharide-consuming Saccharomyces cerevisiae strains is a promising approach for the effective utilization of lignocellulosic biomass and development of economic industrial fermentation processes.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Demi T. Djajadi, Livia B. Brenelli, Telma T. Franco, Lisbeth G. Thygesen, Henning Jorgensen
Summary: This study investigates the effects of lignosulfonate properties and reaction conditions on protein precipitation from green biomass juice. High molecular weight LS has a higher precipitation yield and pH is more important than LS concentration for precipitation. Using high molecular weight LS at optimum conditions can improve protein precipitation yield without affecting digestibility.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Lauana Pereira de Oliveira, Bruno Viana Navarro, Joao Pedro de Jesus Pereira, Adriana Rios Lopes, Marina C. M. Martins, Diego Mauricio Riano-Pachon, Marcos Silveira Buckeridge
Summary: This study comprehensively analyzed the sequences and expression levels of enzymes involved in trehalose metabolism in sugarcane, and specifically investigated the post-translational modifications and residues involved in catalysis and substrate binding of trehalose-6-phosphate synthase. The findings revealed the presence of multiple genes related to trehalose metabolism in sugarcane, and identified differences in enzyme activity between TPS Class I and TPS Class II.
SCIENTIFIC REPORTS
(2022)
Article
Agricultural Engineering
Livia B. Brenelli, Rakesh Bhatia, Demi T. Djajadi, Lisbeth G. Thygesen, Sarita C. Rabelo, David J. Leak, Telma T. Franco, Joe A. Gallagher
Summary: This study investigated the production of xylo-oligosaccharides (XOS) from sugarcane straw (SCS) using steam explosion (SE) pretreatment at pilot-scale, as well as co-production of fermentable sugars and lignin-rich residues for bioethanol and bioenergy, respectively. The SE conditions led to high yields of soluble XOS and fermentable glucose, as well as increased energy content of the saccharified SCS residues.
BIORESOURCE TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Joni E. Lima, Luis H. D. Serezino, Melissa K. Alves, Andre L. Tagliaferro, Marielle Vitti, Silvana Creste, Diego M. Riano-Pachon, Renato dos Santos, Antonio Figueira
Summary: The regulation of nitrate uptake in sugarcane roots is influenced by the physiological status of the plant and is likely determined by transcriptional and posttranscriptional mechanisms. The expression of nitrate transporter genes plays a crucial role in modulating nitrate uptake and nitrogen use efficiency in sugarcane roots.
MOLECULAR GENETICS AND GENOMICS
(2022)
Article
Biotechnology & Applied Microbiology
Gabriela M. Monteiro-Lobato, Pedro S. T. Russo, Flavia V. Winck, Luiz H. Catalani
Summary: Stepwise digestion was developed to prepare a competent biomaterial for osteogenesis from three different ECM sources. The digestion protocol using pepsin under acidic conditions yielded a higher concentration of bioactive residues. The stepwise approach preserved the secondary structures better. Protein profiles of the digested ECMs were highly diverse and tissue-specific. Digestion products from pericardium ECM promoted proliferation and differentiation of bone marrow mesenchymal stem cells to mature osteoblasts.
BIOMED RESEARCH INTERNATIONAL
(2022)
Article
Cell Biology
Lucca de Filipe Rebocho Monteiro, Lais Albuquerque Giraldi, Flavia Vischi Winck
Summary: Under nitrogen deprivation, Chlamydomonas reinhardtii exhibits increased triacylglycerol (TAG) production, but reduced cell growth. Through reanalysis of omics data, this study identified a strong correlation between amino acid metabolism, especially arginine, glutamate, and ornithine pathways, and TAG synthesis. Furthermore, signaling cascades and post-translational modifications (such as phosphorylation, nitrosylation, and peroxidation) were found to be important in this process.
Editorial Material
Biology
Gustavo Schiavone Crestana, Jessica Mendes, Renato Augusto Correa dos Santos, Flavia Vischi Winck
Summary: Brazil needs a long-term strategy for science and innovation to enhance the status of both science and scientists in the country.
Correction
Multidisciplinary Sciences
Carolina da Silveira Bueno, Fabio Kenji Masago, Jose Maria Ferreira Jardim da Silveira, Bruna de Souza Moraes, Leonardo Brantes Bacellar Mendes, Ivette Raymunda Luna, Telma Teixeira Franco
AFRICAN JOURNAL OF SCIENCE TECHNOLOGY INNOVATION & DEVELOPMENT
(2022)
Article
Multidisciplinary Sciences
Beatriz Rodrigues Estevam, Diego Mauricio Riano-Pachon
Summary: Sequence logos are an effective method to display aligned sequences and identify conserved patterns. A new tool has been developed to generate sequence logos at the codon level for protein-coding sequences, allowing for a more accurate analysis of synonymous and non-synonymous changes. The tool provides control over data redundancy, plot types, and alphabet colors.
Article
Biotechnology & Applied Microbiology
Sung-Yeoul Kim, Vikash Chandra Roy, Jin-Seok Park, Byung-Soo Chun
Summary: This study aims to extract functional substances from Undaria pinnatiida sporophyll using supercritical carbon dioxide (SC-CO2) and subcritical water extraction (SWE). The results showed that the consecutive green extraction method can yield extracts rich in fucoxanthin and beta-carotene, and the sporophyll of Undaria pinnatiida contains health-beneficial fatty acids. Additionally, SWE can extract substances with antioxidant, antibacterial, and antihypertensive activities.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2024)