Article
Food Science & Technology
Tariq Aziz, Abid Sarwar, Jalal Ud Din, Sam Al Dalali, Ayaz Ali Khan, Zia Ud Din, Zhennai Yang
Summary: This study revealed that probiotic L. plantarum 12-3 can convert linoleic acid into various fatty acid derivatives, with in vitro studies confirming the enzymatic reactions responsible for this conversion. Putative candidate enzymes involved in the transformation were identified through whole-genome analysis, offering further insights into the mechanism of how beneficial fatty acid metabolites are produced in probiotic L. plantarum.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Agriculture, Dairy & Animal Science
Xin-Xin Liu, Hong-Yun Zhang, Xin Song, Ying Yang, Zhi-Qiang Xiong, Yong-Jun Xia, Lian-Zhong Ai
Summary: The study found that the CLA biotransformation abilities of different Lactobacillus plantarum strains significantly depended on the transcriptional maintenance of cla-hy, cla-dh, and cla-dc. A high transcriptional level in the exponential phase did not necessarily lead to high CLA production, and there was a correlation between CLA production and increased levels of cla-hy transcription.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Multidisciplinary Sciences
Taro Ko, Hiroki Murakami, Azusa Kamikouchi, Hiroshi Ishimoto
Summary: Lactic acid bacteria (LAB) have multiple influences on host brain function through the production of active metabolites in the gut. However, little is known about the biogenic effects of LAB on host brain function. In this study, we found that the Lactobacillus plantarum SBT2227 promoted sleep in Drosophila melanogaster and the involvement of neuropeptide F in this sleep-promoting action.
Article
Microbiology
Arum Darmastuti, Pratama N. Hasan, Rachma Wikandari, Tyas Utami, Endang S. Rahayu, Dian Anggraini Suroto
Summary: The adhesion properties of Lactobacillus plantarum Dad-13 and Mut-7 to the intestinal mucosa of Sprague Dawley rats were studied, showing their ability to adhere to the surface of the rat intestine. Genomic analysis revealed genes related to adhesion properties in both strains, suggesting their potential role in increasing probiotics' adherence to the intestinal mucosa.
Article
Food Science & Technology
Angel Urbina, Fernando Calderon, Santiago Benito
Summary: The study proposes a novel alternative for winemaking by using a combination of different microorganisms to improve wine quality and reduce risks associated with the traditional fermentation process.
Article
Food Science & Technology
Pin Chen, Xiaoqian Chen, Wei Yu, Bo Zhou, Lihua Liu, Yuzhuo Yang, Peng Du, Libo Liu, Chun Li
Summary: This experiment investigated the effects of the antibiotic Ciprofloxacin on key enzymes and intracellular metabolites of Lactobacillus plantarum DNZ-4. The results showed that Ciprofloxacin significantly decreased the activity of certain enzymes and caused changes in intracellular fatty acids, carbohydrates, and amino acids. These findings are important for the development of effective probiotics preparation products.
FOOD SCIENCE AND HUMAN WELLNESS
(2022)
Article
Biotechnology & Applied Microbiology
Xin-Xin Liu, Zhi-Qiang Xiong, Guang-Qiang Wang, Li-Feng Wang, Yong-Jun Xia, Xin Song, Lian-Zhong Ai
Summary: The study identified a novel transcriptional regulator, LTTR, that regulates the production of CLA by activating the transcription of cla-dh and cla-dc in Lactobacillus plantarum. Additionally, it revealed that the transcription of IttR is activated by LA, leading to increased CLA production.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Sihyun Jeong, Yuju Kim, Soyeong Park, Doyeon Lee, Juho Lee, Shwe Phyu Hlaing, Jin-Wook Yoo, Sang Hoon Rhee, Eunok Im
Summary: In this study, the potential mechanisms underlying the anticancer effect of Lactobacillus plantarum metabolites were investigated. The results showed that the metabolites had a synergistic effect with chloroquine, reducing cell viability and downregulating the expression of autophagy-related proteins in Caco-2 cells. This study provides new insights into new therapeutic methods via inhibiting autophagy.
Article
Biochemistry & Molecular Biology
Zhichao Zhang, Shiva Emami, Marie Hennebelle, Rhianna K. Morgan, Larry A. Lerno, Carolyn M. Slupsky, Pamela J. Lein, Ameer Y. Taha
Summary: The study showed that dietary 13-HODE can be absorbed and incorporated into peripheral tissues from esterified plasma lipid pools. Unesterified d4-13-HODE was rapidly eliminated from plasma with a half-life of 1 min following IV injection. Esterified tracer preferentially incorporated into liver, adipose, and heart compared to unesterified d4-13-HODE.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
(2021)
Article
Food Science & Technology
Musu Zha, Kangning Li, Wenyi Zhang, Zhihong Sun, Lai-Yu Kwok, Bilige Menghe, Yongfu Chen
Summary: The study demonstrated that the novel probiotic Lactobacillus plantarum P9 effectively fermented milk and maintained stability during cold storage. Significant changes were observed in the milk metabolome after fermentation and different periods of cold storage, with some metabolites offering functional attributes to the final products. These findings provide valuable insights for the future development and improvement of fermented dairy products using the P9 strain.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Erdong Yuan, Miao Zhou, Zhengyang Liang, William Kwame Amakye, Chuanli Hou, Jiaoyan Ren
Summary: Our study aims to provide a framework for the isolation of potential effective fractions from sturgeon protein guided by probiotic adhesion. We found that Fr2, one of the fractions obtained through anion exchange resin column, significantly increased the intestinal adhesion rates of LP45 and LGG. The primary structure of the protein 14.3 kDa in Fr2 was identified using mass spectrometry.
Article
Green & Sustainable Science & Technology
Qian He, Wei Zhou, Xiaoyang Chen, Qing Zhang
Summary: The ensiling density and lactic acid bacteria inoculant have significant impact on fermentation parameters, bacterial communities, and metabolites of B. papyrifera leaves silage. Silages with higher density showed better fermentation parameters and bacterial community. The lactic acid bacteria inoculant improved the fermentation quality of the silage.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Biotechnology & Applied Microbiology
Azlina Mohd Danial, Angel Medina, Naresh Magan
Summary: The study examined the anti-fungal activity of LABs isolated from Malaysian fermented foods against Trichophyton species. Among 66 LAB strains tested, four were found to effectively inhibit the growth of T. rubrum. Further analysis showed that the supernatant of Lactobacillus plantarum strain HT-W104-B1 contained metabolites that inhibited the growth of T. rubrum, with L-lactic acid and acetic acid being the major compounds. The natural mixture in the supernatants demonstrated significant control over the growth of T. rubrum compared to individual compounds.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Neelja Singhal, Nambram Somendro Singh, Shilpa Mohanty, Manish Kumar, Jugsharan Singh Virdi
Summary: The study reported the isolation and evaluation of probiotic capabilities of Lactiplantibacillus plantarum strains from rhizospheric soil, which showed strong hypocholesterolemic potential and resistance to various environmental stresses, as well as exhibited resistance to acidic environment and multiple antibiotics. Further investigation is recommended for its potential as a potent probiotic with hypocholesterolemic biotherapeutic benefits, and the potential of exploring rhizosphere as a niche for isolating microorganisms with probiotic potential.
SCIENTIFIC REPORTS
(2021)
Article
Nutrition & Dietetics
Rafli Zulfa Kamil, Agnes Murdiati, Mohammad Juffrie, Endang Sutriswati Rahayu
Summary: This study evaluated the efficacy of L. plantarum Dad-13 in preventing the progression of severe undernutrition. The results showed that the probiotic group had better improvements in anthropometry and nutritional status. L. plantarum Dad-13 also modulated the gut microbiota, increasing the number of butyric acid-producing bacteria and inhibiting the growth of Enterobacteriaceae. This gut modulation was associated with an increase in short-chain fatty acids, especially total SCFA, propionic, and butyric acid.
