Article
Nutrition & Dietetics
Angela S. Donin, Claire M. Nightingale, Michael R. Perkin, Michael Ussher, Susan A. Jebb, Rikard Landberg, Paul Welsh, Naveed Sattar, Peymane Adab, Chris G. Owen, Alicja R. Rudnicka, Derek G. Cook, Peter H. Whincup
Summary: Intervening with breakfast cereals to increase cereal fiber intake in children is a feasible and effective method. The high-fiber group showed significant increases in cereal fiber intake and plasma total alkylresorcinol concentration compared to the low-fiber group.
JOURNAL OF NUTRITION
(2021)
Article
Pharmacology & Pharmacy
Minhan Dai, Luis Furuya-Kanamori, Asma Syed, Lifeng Lin, Qiang Wang
Summary: This study aimed to investigate the difference between randomized controlled trials (RCTs) and non-randomized studies of interventions (NRSIs) in the evaluation of adverse events. The results showed no substantial difference in the effects between RCTs and NRSIs when they have similar sample sizes, suggesting that evidence from NRSIs can be considered as a supplement to RCTs for safety assessment.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Computer Science, Information Systems
Mohammadreza Qaraei, Saeid Abbaasi, Kamaledin Ghiasi-Shirazi
Summary: The study introduces a network called Randomized Nonlinear PCANet (RNPCANet) which uses kernel PCA to learn convolutional filters, addressing the limitation of PCANet in capturing nonlinear structures. By leveraging kernel methods, the proposed method achieves superior recognition accuracy in image recognition tasks compared to PCANet and CKNs.
INFORMATION SCIENCES
(2021)
Article
Multidisciplinary Sciences
Maryam Binesh, Narges Shafaroodi, Majid Mirmohammadkhani, Rokhsareh Aghili, Fatemeh Motaharinezhad, Mahnoosh Khanipour, Afsoon Hassani Mehraban
Summary: This study evaluated the effectiveness of Occupational Therapy Diabetes Self-Management intervention (OTDSM) in improving glycemic stability and self-management skills in individuals with type-2 diabetes. The results showed significant differences between the intervention and control groups in terms of hemoglobin A1C levels, self-management behaviors, self-efficacy, and performance and satisfaction with daily routines (P < 0.05). Inclusion of occupational therapy protocol in the care plan for people with diabetes can lead to improved health outcomes by promoting their involvement in self-management activities.
SCIENTIFIC REPORTS
(2023)
Article
Clinical Neurology
Feiyang Guo, Tingting Zhao, Qianglan Zhai, Xiaolin Fang, Haoze Yue, Fang Hua, Hong He
Summary: This study aimed to evaluate the prevalence and characteristics of spin in randomized controlled trial (RCT) abstracts published in sleep medicine journals and identify factors associated with its presence and severity. The results showed that out of 114 included RCT abstracts, 89 (78.1%) were identified as having at least one type of spin strategy. The presence of spin varied significantly based on the research area and the involvement of statisticians. The study highlights the need for collective efforts to eliminate spin in future sleep medicine publications.
Article
Health Care Sciences & Services
Feiyang Guo, Wengwanyue Ye, Danchen Qin, Xiaolin Fang, Fang Hua, Hong He
Summary: This study assessed the reporting quality and spin in pediatric dentistry RCT abstracts and found that the reporting quality was suboptimal with a high prevalence of spin.
BMC MEDICAL RESEARCH METHODOLOGY
(2023)
Article
Computer Science, Artificial Intelligence
Fenglei Yang, Jingling Han, Baomin Li
Summary: In this paper, an intervention approach is proposed to learn a deconfounded classification model, formulated as causal inference to derive a causal effect formula. The WAE (Wasserstein Auto-Encoder) objective is expanded for classification, with a new regularizer defined for learning unobserved confounders, leading to significant improvement on imbalanced data in experimental results.
INTERNATIONAL JOURNAL OF MACHINE LEARNING AND CYBERNETICS
(2022)
Article
Nursing
Dongguang Wang, Lian Wang, Xiang Tong, Sitong Liu, Hong Fan, Yonggang Zhang
Summary: Nurse-led models of care are effective in improving health management and reducing hospitalizations. However, there is variation in the reporting quality of studies in this field, and a lack of literature evaluation. This study aimed to assess the reporting quality and spin of abstracts of published randomized controlled trials with statistically not significant primary outcomes, and identify factors associated with spin.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2023)
Meeting
Health Care Sciences & Services
Dongguang Wang, Lingmin Chen, Lian Wang, Fang Hua, Juan Li, Yuxi Li, Yonggang Zhang, Hong Fan, Weimin Li, Mike Clarke
Summary: The study assessed the reporting quality of abstracts for published randomized controlled trials (RCTs) of COVID-19 interventions, finding a significant correlation between abstract word count and reporting scores, as well as identifying multiple spin strategies. Geographical origin was associated with the severity of spin, with research from non-Asian regions containing fewer spin strategies.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2021)
Article
Multidisciplinary Sciences
Hannah Nett, Julius Steegmann, Birgit Tollkuehn-Prott, Frank Hoelzle, Ali Modabber
Summary: Postoperative nutritional intervention in patients with oral cancer can improve their nutritional status, reduce postoperative complaints, and decrease morbidity and mortality.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Deborah A. Hall, Robin M. Voigt, Thaisa M. Cantu-Jungles, Bruce Hamaker, Phillip A. Engen, Maliha Shaikh, Shohreh Raeisi, Stefan J. Green, Ankur Naqib, Christopher B. Forsyth, Tingting Chen, Richard Manfready, Bichun Ouyang, Heather E. Rasmussen, Shahriar Sedghi, Christopher G. Goetz, Ali Keshavarzian
Summary: This study found that prebiotic intervention can beneficially change the microbiome, decrease inflammation and a marker of neurodegeneration, with possible clinical effects in Parkinson's disease (PD) patients.
NATURE COMMUNICATIONS
(2023)
Article
Health Care Sciences & Services
Mona Ghannad, Bada Yang, Mariska Leeflang, Adrian Aldcroft, Patrick M. Bossuyt, Sara Schroter, Isabelle Boutron
Summary: The study aimed to estimate the effect of an intervention compared to usual peer-review process on reducing spin in abstract conclusions of biomedical study reports. Results showed that the short instructions to authors did not significantly reduce spin, suggesting the need for evaluation of other interventions to reduce spin in research reports.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2021)
Article
Multidisciplinary Sciences
Shokoufeh Aalaei, Mahnaz Amini, Fariborz Rezaeitalab, Hadi Asadpour, Hamed Tabesh, Farnaz Khoshrounejad, Saeid Eslami, Lahya Afshari Saleh
Summary: An educational intervention was successful in improving the adherence rate of patients to prescribed sleep test, however, there is still room for improvement. The most common barriers affecting patients to undergo sleep testing were time limitations, condition improvement, and high cost of diagnostic test.
Article
Public, Environmental & Occupational Health
Jenn A. Leiferman, Angela E. Lee-Winn, Rachael Lacy, James F. Paulson
Summary: Prenatal depression has negative effects on maternal and child health, and providers play a crucial role in managing it. A randomized controlled trial tested the effects of an online training on providers' self-reported practices related to prenatal depression. The results showed that the intervention group had improved satisfaction with mental health services and increased screening, counseling, and referral practices for prenatal depression.
WOMENS HEALTH ISSUES
(2023)
Article
Medicine, Research & Experimental
Yan He, Rong Zhang, Wenjing Shan, Yuhuan Yin, Xiaoli Zhang, Yiyin Zhang, Xiaoping Wang
Summary: This study evaluated whether abstract reports in nursing adhered to the Consolidated Standards of Reporting Trials for Abstracts (CONSORT-A) guideline after 2010, and explored factors associated with adherence. The study found that adherence to abstract reporting in nursing literature has improved since the CONSORT-A era, but overall completeness of RCT abstracts remained low.
Article
Computer Science, Interdisciplinary Applications
Guillaume Cabanac, Theodora Oikonomidi, Isabelle Boutron
Summary: Preprints play a vital role in open and rapid communication of non-peer reviewed research, but existing preprint servers have limitations in identifying all preprint-publication links. To address this issue, a more thorough approach is necessary to improve the accuracy of information retrieval tasks related to preprint-publication links.
Review
Medicine, General & Internal
Matthew J. Page, Joanne E. McKenzie, Patrick M. Bossuyt, Isabelle Boutron, Tammy C. Hoffmann, Cynthia D. Mulrow, Larissa Shamseer, Jennifer M. Tetzlaff, Elie A. Akl, Sue E. Brennan, Roger Chou, Julie Glanville, Jeremy M. Grimshaw, Asbjorn Hrobjartsson, Manoj M. Lalu, Tianjing Li, Elizabeth W. Loder, Evan Mayo-Wilson, Steve McDonald, Luke A. McGuinness, Lesley A. Stewart, James Thomas, Andrea C. Tricco, Vivian A. Welch, Penny Whiting, David Moher
Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Health Care Sciences & Services
Olivier Pierre, Carolina Riveros, Sarah Charpy, Isabelle Boutron
Summary: The study assessed the sensitivity of two secondary electronic sources of COVID-19 studies, with the L.OVE platform showing better performance in identifying research reports.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Health Care Sciences & Services
Astrid Chevance, Axel Fortel, Adeline Jouannin, Faustine Denis, Marie-France Mamzer, Philippe Ravaud, Stephanie Sidorkiewicz
Summary: Digital pills face limitations in prospective acceptability and willingness to use, primarily due to clinical and ethical concerns. Results indicate that willingness to take digital pills is associated with gender and the current use of connected devices to record health settings.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Health Care Sciences & Services
Van Thu Nguyen, Philippe Ravaud, Viet Thi Tran, Bridget Young, Isabelle Boutron
Summary: The study investigates patients' preferences for the organization of randomized controlled trials (RCTs) and finds that most patients prefer a hybrid model involving both on-site and remote visits. Patients are more likely to participate in a trial organized according to their preferences.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Review
Health Care Sciences & Services
Gloria A. Aguayo, Catherine Goetzinger, Renza Scibilia, Aurelie Fischer, Till Seuring, Viet-Thi Tran, Philippe Ravaud, Tamas Bereczky, Laetitia Huiart, Guy Fagherazzi
Summary: Patient and public involvement (PPI) in research is important for improving the quality and relevance of studies. Various methods, including workshops, surveys, and focus groups, are commonly used for PPI in epidemiological research. Recommendations include early integration of PPI, combining methods for idea generation, and utilizing digital tools for e-cohorts.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Health Care Sciences & Services
Tat-Thang Vo, Aidan Cashin, Cecilia Superchi, Pham Hien Trang Tu, Thanh Binh Nguyen, Isabelle Boutron, David MacKinnon, Tyler Vanderweele, Hopin Lee, Stijn Vansteelandt
Summary: The bias assessment practice in recently published systematic reviews of mediation studies is found to be suboptimal, with a lack of consensus, rigorous development, and validation of assessment tools. A consensus-based bias assessment tool specifically designed for mediation studies is needed to improve the quality and consistency of assessments.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Medicine, General & Internal
Philipp Kapp, Laura Esmail, Lina Ghosn, Philippe Ravaud, Isabelle Boutron
Summary: In the context of the COVID-19 pandemic, this study compared the reporting characteristics of randomized controlled trials (RCTs) between preprints and peer-reviewed publications. The results showed that transparency, completeness, and consistency of reporting of COVID-19 clinical trials were insufficient in both preprints and peer-reviewed publications. There were no major improvements after the journal peer review process.
Editorial Material
Health Care Sciences & Services
Ruth Stewart, Isabelle Boutron, Elie A. Akl
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Article
Health Care Sciences & Services
Dimitris Mavridis, Adriani Nikolakopoulou, Irini Moustaki, Anna Chaimani, Raphael Porcherd, Isabelle Boutron, Philippe Ravaud
Summary: This study presents graphical methods to group interventions and uses conjoint analysis to place weights on outcomes based on stakeholders' preferences. The results provide valuable information about the clustering of interventions. Grouping interventions helps decision makers identify optimal options in terms of benefit-risk balance and choose interventions from the best cluster based on other factors such as cost and implementation.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Article
Mathematical & Computational Biology
Theodoros Evrenoglou, Isabelle Boutron, Georgios Seitidis, Lina Ghosn, Anna Chaimani
Summary: Outputs from living evidence syntheses projects have been widely used during the pandemic to provide evidence-based recommendations. However, stakeholders also need to understand the data and perform their own exploratory analyses. To assist them, a metaCOVID application has been created in R to facilitate fast data exploration and tailored sub-analyses.
RESEARCH SYNTHESIS METHODS
(2023)
Article
Health Care Sciences & Services
Mauricia Davidson, Theodoros Evrenoglou, Carolina Grana, Anna Chaimani, Isabelle Boutron
Summary: This study evaluated the difference in summary treatment effect estimates between preprint and peer-reviewed journal trials in the context of COVID-19. The results showed that there was no significant difference in summary effect estimates between preprint and peer-reviewed journal trials.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Review
Health Care Sciences & Services
Erlend Faltinsen, Adnan Todorovac, Isabelle Boutron, Lesley A. Stewart, Asbjorn Hrobjartsson, Andreas Lundh
Summary: The study compares the contemporary Cochrane review approach with a structured approach for retrieving information on trial funding and researchers' conflicts of interest, and finds that the structured approach is more effective in obtaining this information.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Article
Dermatology
Laura Fertitta, Kavita Y. Sarin, Christina Bergqvist, Ekshika Patel, Bastien Peiffer, Sabine Moryousef, Marie-Laure Armand, Arnaud Jannic, Salah Ferkal, Philippe Ravaud, Viet-Thi Tran, Jaishri O. Blakeley, Carlos G. Romo, Khaled Ezzedine, Pierre Wolkenstein
Summary: This study first defined severity strata for cutaneous neurofibromas using an anchoring approach. After validation in French and United States populations, the cNF-Skindex and the strata showed a strong correlation in interpreting cutaneous neurofibromas in daily practice and clinical trials.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2023)