Hepatitis C virus enhances Rubicon expression, leading to autophagy inhibition and intracellular innate immune activation

Suppression of autophagic activity by Rubicon is a signature of aging

(2019) Shuhei Nakamura et al.   Nature Communications

Combinations of two drugs among NS3/4A inhibitors, NS5B inhibitors and non-selective antiviral agents are effective for hepatitis C virus with NS5A-P32 deletion in humanized-liver mice

(2019) Akira Doi et al.   JOURNAL OF GASTROENTEROLOGY

Effects of resistance‐associated variants in genotype 2 hepatitis C virus on viral replication and susceptibility to antihepatitis C virus drugs

(2019) Goki Suda et al.   HEPATOLOGY RESEARCH

Frequent NS5A and multiclass resistance in almost all HCV genotypes at DAA failures: What are the chances for second-line regimens?

(2018) Velia Chiara Di Maio et al.   JOURNAL OF HEPATOLOGY

Induction of selective autophagy in cells replicating hepatitis C virus genome

(2018) Hiroyuki Mori et al.   JOURNAL OF GENERAL VIROLOGY

Comparison of direct sequencing and Invader assay for Y93H mutation and response to interferon-free therapy in hepatitis C virus genotype 1b

(2017) Kazuhiko Hayashi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepatitis C virus infection

(2017) Michael P. Manns et al.   Nature Reviews Disease Primers

The autophagy elongation complex (ATG5-12/16L1) positively regulates HCV replication and is required for wild-type membranous web formation

(2017) Ahmed M. Fahmy et al.   Scientific Reports

Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice

(2016) Satoshi Tanaka et al.   HEPATOLOGY

Hepatitis C Virus–Associated Cancer

(2015) Ming V. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Emergence of hepatitis C virus NS5A L31V plus Y93H variant upon treatment failure of daclatasvir and asunaprevir is relatively resistant to ledipasvir and NS5B polymerase nucleotide inhibitor GS-558093 in human hepatocyte chimeric mice

(2015) Yugo Kai et al.   JOURNAL OF GASTROENTEROLOGY

Autophagy in HCV Infection: Keeping Fat and Inflammation at Bay

(2014) Tiziana Vescovo et al.   Biomed Research International

Interferon-stimulated genes and their role in controlling hepatitis C virus

(2013) Philippe Metz et al.   JOURNAL OF HEPATOLOGY

Hepatitis C Virus Upregulates Beclin1 for Induction of Autophagy and Activates mTOR Signaling

(2012) Shubham Shrivastava et al.   JOURNAL OF VIROLOGY

Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication

(2012) Inés Romero-Brey et al.   PLoS Pathogens

ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication

(2011) A. Raychoudhuri et al.   JOURNAL OF VIROLOGY

Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro

(2010) Po-Yuan Ke et al.   JOURNAL OF CLINICAL INVESTIGATION

Ultrastructural and biochemical analyses of hepatitis C virus-associated host cell membranes

(2010) P. Ferraris et al.   JOURNAL OF GENERAL VIROLOGY

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication

(2010) D. Sir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Phase Transfer Surfactant-Aided Trypsin Digestion for Membrane Proteome Analysis

(2008) Takeshi Masuda et al.   JOURNAL OF PROTEOME RESEARCH

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY