Article
Orthopedics
Tessa De Vrieze, Nick Gebruers, Ines Nevelsteen, Sarah Thomis, An De Groef, Wiebren A. A. Tjalma, Jean-Paul Belgrado, Liesbeth Vandermeeren, Chris Monten, Marianne Hanssens, Anne Asnong, Lore Dams, Elien Van der Gucht, An-Kathleen Heroes, Nele Devoogdt
Summary: The study found that fluoroscopy-guided MLD, traditional MLD, and placebo MLD had similar effectiveness when added to DLT for treating chronic BCRL. The improvement in reducing local tissue water, extracellular fluid, skin thickness, and improving skin elasticity and fibrosis was limited.
Article
Multidisciplinary Sciences
Yuiko Suzuki, Yukari Nakajima, Toshio Nakatani, Mayumi Okuwa, Junko Sugama
Summary: This study aimed to identify the normal hindlimb lymphatic systems in rats and compare them with detours after lymphatic flow blockage. The results revealed three types of detours located in the fatty layer above the panniculus carnosus muscle, characterized by wide lumina, which were suggested to be pre-collecting lymphatic vessels. The detours observed after lymphatic blockage were different from the normal rat lymphatic system, suggesting a potential new method for simple lymphatic drainage.
Article
Oncology
Yan Lin, Yan Yang, Xiaoyu Zhang, Wandi Li, Haoran Li, Dali Mu
Summary: This systematic review and meta-analysis evaluated the effectiveness of manual lymphatic drainage (MLD) on breast cancer-related lymphedema (BCRL) patients. The findings demonstrate that MLD significantly improves pain in BCRL patients, but does not have significant effects on volumetric changes of lymphedema and quality of life. The potential preventive effect of MLD on BCRL requires further discussion.
CLINICAL BREAST CANCER
(2022)
Article
Dermatology
Jingyi Liu, Di Chen, Xiaoting Yin
Summary: The aim of this study was to explore the application value of manual lymphatic drainage combined with vacuum sealing drainage in axillary web syndrome (AWS) after breast cancer surgery. The results showed that compared with the control group, the study group had significant improvements in the duration time to the disappearance of clinical symptoms, degree of pain, upper limb disability function, and quality of life.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Medicine, General & Internal
Jose Maria Pereira de Godoy, Livia Maria Pereira de Godoy, Henrique Jose Pereira de Godoy, Maria de Fatima Guerreiro Godoy
Summary: Manual lymphatic therapy (MLT) (Godoy method) is effective in reducing the development of lymphedema after breast cancer treatment.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Orthopedics
Tessa De Vrieze, Nick Gebruers, Ines Nevelsteen, Steffen Fieuws, Sarah Thomis, An De Groef, Wiebren A. A. Tjalma, Jean-Paul Belgrado, Liesbeth Vandermeeren, Chris Monten, Marianne Hanssens, Nele Devoogdt
Summary: In patients with chronic BCRL, adding manual lymphatic drainage (MLD) to decongestive lymphatic therapy (DLT) did not provide clinically important additional benefit.
JOURNAL OF PHYSIOTHERAPY
(2022)
Article
Medicine, General & Internal
Kuo-Yang Tsai, Su-Fen Liao, Kuan-Lin Chen, Hao-Wei Tang, Hsin-Ya Huang
Summary: This study compared the short-term effects of early interventions with rehabilitation exercise versus manual lymphatic drainage (MLD) and rehabilitation exercise in patients with oral cancer after surgery. The results showed that early intervention significantly improved pain, range of motion (ROM), and lymphedema in the patients. Moreover, the use of MLD intervention showed more improvement in neck lateral flexion and skin-to-bone distance in the jaw.
Article
Surgery
Leslie N. N. Kim, Babak Mehrara, Joseph Dayan, Leslie McGrath, Michelle Coriddi
Summary: Current predictive models cannot accurately predict who will develop lymphedema. The presence of accessory lymphatic pathways may improve lymphatic drainage and result in smaller limb volumes. Further research is needed to understand these pathways and their impact on symptoms and quality of life.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Surgery
Brielle Weinstein, Nicole K. Le, Ellen Robertson, Amanda Zimmerman, Tina Tavares, Thanh Tran, Christine Laronga, Nicholas J. Panetta
Summary: This study investigated the therapeutic effect of immediate lymphaticovenular anastomosis on breast cancer-related lymphedema. The results showed that immediate lymphaticovenular anastomosis significantly reduced the incidence of breast cancer-related lymphedema in high-risk patients, while combined adjuvant treatment increased the risk of developing breast cancer-related lymphedema in patients.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Surgery
Michelle Coriddi, Joseph Dayan, Emily Bloomfield, Leslie Mcgrath, Richard Diwan, Jasmine Monge, Julia Gutierrez, Stav Brown, Lillian Boe, Babak Mehrara
Summary: The study aims to examine the efficacy of immediate lymphatic reconstruction (ILR) for reducing the incidence of breast cancer-related lymphedema (BCRL) after axillary lymph node dissection (ALND). Preliminary results show that ILR can decrease the occurrence of BCRL.
Article
Oncology
Jia Qiao, Li-ning Yang, Yu-han Kong, Xin Huang, Yi Li, Ding-qun Bai
Summary: The efficacy of manual lymphatic drainage (MLD) for breast cancer-related postmastectomy lymphedema (BCRL) was analyzed in this study. The results showed that there was no significant difference in upper extremity edema between the MLD treatment and control groups. However, significant reductions in upper extremity volume were observed when the treatment course was >= 20 sessions or the duration of treatment was >2 weeks.
Article
Biochemistry & Molecular Biology
Mei Rosemary Fu, Deborah Axelrod, Amber Guth, Melissa L. McTernan, Jeanna M. Qiu, Zhuzhu Zhou, Eunjung Ko, Cherlie Magny-Normilus, Joan Scagliola, Yao Wang
Summary: Obesity has a significant impact on lymphatic pain and arm swelling in breast cancer patients, with the greatest effects seen on lymphatic pain and arm swelling. Further research is needed to explore inflammatory pathways and molecular mechanisms for potential treatments.
Review
Surgery
Julia Roka-Palkovits, Miffy Chia-Yu Lin, Chieh-Han J. Tzou, Ines Tinhofer, Ming-Huei Cheng
Summary: Vascularized lymph node transfer with retrograde manual lymphatic drainage significantly improves the treatment outcomes for extremity lymphedema patients, with better results observed in distal recipient sites.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Health Care Sciences & Services
Gabriela Duran-Aguilar, Alberto Rossa-Sierra, Rita Q. Fuentes-Aguilar
Summary: Breast cancer is a common malignant tumor in the United States, Europe, and Mexico, and its treatment can lead to secondary lymphedema. This complication has significant impacts on the health, social, and economic aspects, and physical therapy is important for improving the quality of life in survivors. The design of a lymphatic vessel is proposed as a solution to assist the mechanical failure of the damaged lymphatic system.
Article
Oncology
Joseph Kyu-Hyung Park, Junggyo Seo, Eun Joo Yang, Yusuhn Kang, Chan Yeong Heo, Yujin Myung
Summary: This study aimed to investigate the relationship between lymphatic flow velocity and the efficacy of lymphovenous anastomosis (LVA) in breast cancer-related lymphedema patients. The findings showed a positive correlation between lymphatic flow velocity and surgical outcomes, suggesting that advanced-stage lymphedema patients with high lymphatic flow velocities can benefit from LVA alone.
Article
Medicine, Research & Experimental
Mary S. Dietrich, Katrina Gaitatzis, Louise Koelmeyer, John Boyages, Vandana G. Abramson, Sarah A. McLaughlin, Nicholas Ngui, Elisabeth Elder, James French, Jeremy Hsu, T. Michael Hughes, Deonni P. Stolldorf, Chirag Shah, Sheila H. Ridner
Summary: A compression intervention for subclinical breast cancer-related lymphedema led to improvements in physical, emotional, and quality-of-life outcomes. The study found that greater changes in extracellular fluid and whole-arm volume were associated with higher symptom, skin condition, and quality-of-life values in patients with S-BCRL. Prospective surveillance and compression interventions were effective in reducing progression rates from S-BCRL to C-BCRL.
LYMPHATIC RESEARCH AND BIOLOGY
(2023)
Article
Oncology
Helen Mackie, Belinda M. Thompson, Louise A. Koelmeyer, Robbie Blackwell, Katrina Gaitatzis, Asha Heydon-White, John Boyages, Hiroo Suami
Summary: This study used ICG lymphography to determine that 16.9% of patients with lower-limb lymphedema have a compensatory lymphatic drainage pathway from the affected limb to the contralateral inguinal lymph node region, particularly observed in unilateral cancer-related lymphedema with edema in the proximal thigh, inguinal, pubic, and lower abdominal regions. Directing manual lymphatic drainage to the contralateral inguinal drainage region should be considered especially for patients with cancer-related LLLE.
REHABILITATION ONCOLOGY
(2023)
Article
Sport Sciences
Darryl E. Hands, Xanne A. K. Janse de Jonge, G. C. Livingston, Nattai R. Borges
Summary: This study examined the effects of match location and travel modality on the physical performance of an Australian A-League football team. The results showed that away matches had higher average running intensity and low-speed activity, while home matches had higher high-speed activity. In terms of travel modality, road travel had higher low-speed activity, while home matches and long-flight travel had higher high-speed activity. Home matches also showed significantly higher very high-speed activity than road travel. Evaluating the impact of travel modality on physical performance provides valuable information for coaches to plan travel and minimize the negative effects on performance.
JOURNAL OF SPORTS SCIENCES
(2023)
Article
Nutrition & Dietetics
Stacy T. Sims, Chad M. Kerksick, Abbie E. Smith-Ryan, Xanne A. K. Janse de Jonge, Katie R. Hirsch, Shawn M. Arent, Susan Joyce Hewlings, Susan M. Kleiner, Erik Bustillo, Jaime L. Tartar, Valerie G. Starratt, Richard B. Kreider, Casey Greenwalt, Liliana I. Renteria, Michael J. Ormsbee, Trisha A. VanDusseldorp, Bill I. Campbell, Douglas S. Kalman, Jose Antonio
Summary: This article summarizes the results of a comprehensive review and critical analysis of the literature on the nutritional concerns of female athletes. The conclusions highlight the importance of tracking hormonal status and individual patterns, achieving adequate energy intake, tailoring carbohydrate intake to hormonal status, consuming high-quality protein close to exercise, and addressing fluid dynamics and electrolyte handling in female athletes. The article also emphasizes the need for more research on sex-specific supplementation and the inclusion of females in research studies.
JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION
(2023)
Article
Medicine, Research & Experimental
Helen Mackie, Belinda Thompson, Asha Heydon-White, Hiroo Suami, Robbie Blackwell, Louise Koelmeyer
Summary: This study used ICG lymphography to investigate the presence of the axillo-inguinal lymphatic drainage pathway in patients with upper and lower extremity lymphedema. The findings suggest that this pathway is not present in upper extremity lymphedema patients and is rare in lower extremity lymphedema patients.
LYMPHATIC RESEARCH AND BIOLOGY
(2023)
Article
Endocrinology & Metabolism
Helen Mackie, Belinda M. Thompson, Hiroo Suami, Asha Heydon-White, Robbie Blackwell, Fiona Tisdall Blake, Louise A. Koelmeyer
Summary: This study used indocyanine green (ICG) lymphography to assess the presence or absence of lymphoedema in the lower limbs of women with lipoedema. The findings suggested that the clear majority of patients did not exhibit symptoms of lymphoedema.
Editorial Material
Physiology
Xanne A. K. Janse de Jonge, Belinda M. Thompson
INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE
(2023)
Article
Surgery
T. Karlsson, H. Mackie, K. Ho-Shon, R. Blackwell, A. Heydon-White, L. Koelmeyer, H. Suami
Summary: Using both ICG lymphography and MRI, this study found that 10 out of 28 patients with unilateral advanced cancer-related lower extremity lymphoedema (LEL) exhibited gluteal lymphoedema. Compared to the non-gluteal lymphoedema group, patients in the gluteal lymphoedema group showed thickened skin and increased gluteal subcutaneous tissue on ICG lymphography, with no significant difference in excess leg volume between the two groups. The severity of gluteal lymphoedema was positively correlated with excess leg volume on the affected side. In conclusion, surgical and conservative management options should be considered for advanced LEL patients.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2023)
Review
Oncology
Cheryl L. Brunelle, John Boyages, Amanda W. Jung, Hiroo Suami, Brooke C. Juhel, Asha Heydon-White, Helen Mackie, Shinn-Huey Shirley Chou, Vincent S. Paramanandam, Louise Koelmeyer, Alphonse G. Taghian
Summary: The diagnosis and treatment of breast lymphedema (BL) after breast-conserving surgery lacks standardized criteria and high-quality studies. There is variability in the incidence, time course, and risk factors for BL. Tissue dielectric constant and ultrasound are emerging as promising assessment tools, but further validation and research are needed.
BREAST CANCER RESEARCH AND TREATMENT
(2023)